View source for Hepatitis B

==Background==
[[File:Prevalence-of-hepatitis-b-surface-antigen.png|thumb|Baseline prevalence of Hepatitis B exposure.]]
*Blood-borne DNA virus
*Incubation period: 1-3 months
*Virus can cause acute, chronic, or asymptomatic infection

==Clinical Features==
[[File:Jaundice08.jpg|thumb|Jaundice of the skin]]
[[File:Jaundice.jpg|thumb|Pediatric jaundice with icterus of sclera.]]
*[[Nausea/vomiting]]
*[[RUQ pain]]
*[[Jaundice]]
*[[Fever]]

==Differential Diagnosis==
{{Acute hepatitis causes}}
{{STD DDX}}

==Evaluation==
*[[LFTs]]
**AST, ALT > 1000s
**Elevated bilirubin
**Elevated alk phophatase
*Elevated INR
*CBC, BMP
*Assess for alternative etiologies of symptoms as appropriate (see: [[jaundice]], [[RUQ pain]], [[nausea/vomiting]])
{{Acute hepatitis panel}}

===Evaluating Hepatitis B Serology Results===
[[File:Hepatitis B serology.jpg|thumb|Hepatitis B serology findings.]]
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Clinical Scenario'''
| align="center" style="background:#f0f0f0;"|'''HBsAg'''
| align="center" style="background:#f0f0f0;"|'''anti-HBc'''
| align="center" style="background:#f0f0f0;"|'''anti-HBs'''
|-
| Susceptible to infection||negative||negative||negative
|-
| Immune due to natural infection||negative||positive||positive
|-
| Immune due to Hep B infection||negative||negative||positive
|-
| Acutely infected||positive||anti-HBc- positive;        IgM anti-HBc- positive||negative
|-
| Chronically infected||positive||anti-HBc- positive;       IgM anti-HBc- negative||negative
|}

==Management==
*Supportive care for acute disease

{{Hepatitis B post exposure prophylaxis}}

==Disposition==
*Consider admission for: 
*INR >2, Bilirubin >30, hypoglycemia
*Any GI bleeding
*Intractable pain, inability to tolerate PO
*Significant comorbidity/immunocompromised or age >50 years

==See Also==
*[[Viral hepatitis]]
*[[Acute hepatitis]]
*[[Jaundice]]

==External Links==
*[[Antibiotics (By_Diagnosis)]]

==References==
<references/>

[[Category:ID]][[Category:GI]]