View source for CMV neurologic disease

==Background==

==Clinical Features<ref>https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_HIV_Guide/545043/all/CMV__neurologic</ref>==
*Typically presents in immunocompromised hosts (e.g. [[AIDS]]) with history of prior CMV illness (e.g. [[CMV retinitis]]
*Usually [[encephalitis]], presenting as a acute, rapid onset, progressive [[encephalopathy]] but can also manifest as polyradiculitis
*Encephalitis:
**Memory impairment with [[dementia]]-like presentation
**[[weakness|Motor deficits]], [[numbness]], [[cranial nerve palsies]]
**[[Ataxia]], [[nystagmus]]
**[[intracranial mass|Mass lesion]] with focal deficits or evidence of mass effect
**+/- [[Fever]]
*Polyradiculitis
**[[Back pain]]/sciatica
**[[Paresthesia]], distal [[numbness|sensory loss]]
**[[Urinary retention]]
**Ascending [[weakness|paralysis]], similar to [[Guillain-Barre]]

==Differential Diagnosis==
{{AMS and fever DDX}}
{{HIV associated conditions}}

==Evaluation==
*Neuroimaging ([[brain MRI|MRI]] more helpful than [[head CT|CT]])
*CMV PCR

==Management==
===Antivirals===
{{CMV neurologic disease treatment}}

==Disposition==
*Admit

==See Also==
*[[Cytomegalovirus (CMV) infection]]

==External Links==

==References==
<references/>
[[Category:ID]] [[Category:Neurology]]