View source for Cetacaine

==General Information==
[[File:cetylite-cetacaine-spray-20g-0220.jpg|thumb|]]
*Brand name of commonly available topical mucosal anesthetic
*Combination of 14% [[benzocaine]], 2% [[tetracaine]] hydrochloride, and 2% butamben
*Slightly different from another readily available topical anesthetic, HurriCaine spray, which is 20% benzocaine

==Administration==
*Type: Topical anesthetic 
*Dosage Forms: Spray, gel, solution
*Routes of Administration: Mucosal 
*Common Trade Names: Cetacaine; Exactacain

==Adult Dosing==
'''Spray form''' 
*Apply maximum 2 second spray

'''Gel form'''
*Apply a maximum of 1 inch of gel

'''Solution form'''
*Apply a maximum of 0.4cc

==Pediatric Dosing==
No pediatric dosing established

==Special Populations==
*[[Drug pregnancy categories|Pregnancy Rating]]: Category C
*Lactation risk: Safety unknown
===Renal Dosing===
*Adult: N/A
*Pediatric: N/A
===Hepatic Dosing===
*Adult: N/A
*Pediatric: N/A

==Contraindications==
*Allergy to class/drug
*Cholinesterase deficincies
*Use caution in G6PD and Hgb-M patients
*Avoid using on significantly inflamed or macerated tissue

==Adverse Reactions==
===Serious===
*[[Methemoglobinemia]]
*[[Anaphylaxis]]

===Common===
*[[Contact dermatitis]]
*Xeroderma

==Pharmacology==
*Half-life: Unknown
*Metabolism: Plasma cholinesterase, liver
*Excretion: Urine (minimal systemic absorption)

==Mechanism of Action==
*Ester anesthetic, inhibits Na ion channels and nerve impulse/conduction

==Comments==


==See Also==


==References==
Micromedex

US FDA benzocaine warning. http://www.fda.gov/Safety/MedWatch/SafetyInformation/SafetyAlertsforHumanMedicalProducts/ucm250264.htm
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[[Category:Pharmacology]]