View source for Colestipol

<languages/>
<translate>

==Administration== <!--T:1-->

<!--T:2-->
*Type: Bile Acid Binder
*Dosage Forms: 1 g tab; 5 g/scoop granules; 5 g granule packet
*Routes of Administration: Oral
*Common Trade Names: N/A


==Adult Dosing== <!--T:3-->

<!--T:4-->
*[[Special:MyLanguage/Digoxin toxicity|Digoxin toxicity]], adjunct tx
**Granules: 5 g PO q6-8h
***Start: 10 g PO x1 within 1-3h after last oral digoxin ingestion
***Max: 30 g/day
*Gallbladder surgery-associated [[Special:MyLanguage/diarrhea|diarrhea]], adjunct tx
**Tabs: 2-16 g/day PO divided QD-QID
***Start: 2 g PO QD-bid
***Max: 16 g/day.
***Do not crush/cut/chew
**Granules:5-30 g/day PO divided QD-QID
***Start: 5 g PO QD-bid
***Max: 30 g/day
*Hypercholesterolemia
**Tabs: 2-16 g/day PO divided QD-QID
***Start: 2 g PO QD-bid
***Max: 16 g/day.
***Do not crush/cut/chew
**Granules:5-30 g/day PO divided QD-QID
***Start: 5 g PO QD-bid
***Max: 30 g/day
*[[Special:MyLanguage/Pruritus|Pruritus]] secondary to biliary obstruction
**Tabs: 2-16 g/day PO divided QD-QID
***Start: 2 g PO QD-bid
***Max: 16 g/day.
***Do not crush/cut/chew
**Granules:5-30 g/day PO divided QD-QID
***Start: 5 g PO QD-bid
***Max: 30 g/day


==Pediatric Dosing== <!--T:5-->

<!--T:6-->
Pediatric dosing currently unavailable.


==Special Populations== <!--T:7-->

<!--T:8-->
*[[Special:MyLanguage/Drug pregnancy categories|Pregnancy Rating]]: C; Inadequate data to assess risk
*Lactation risk: L3; Safety unknown


===Renal Dosing=== <!--T:9-->

<!--T:10-->
*Adult: No adjustment
*Pediatric: N/A

===Hepatic Dosing=== <!--T:11-->

<!--T:12-->
*Adult: Not defined.
*Pediatric: N/A


==Contraindications== <!--T:13-->

<!--T:14-->
*Allergy to class/drug
*Caution if constipation
*Caution if prolonged use


==Adverse Reactions== <!--T:15-->


===Serious=== <!--T:16-->

<!--T:17-->
*Fecal impaction
*[[Special:MyLanguage/PUD|PUD]]
*[[Special:MyLanguage/Cholecystitis|Cholecystitis]]
*[[Special:MyLanguage/Cholelithiasis|Cholelithiasis]]
*Esophageal obstruction


===Common=== <!--T:18-->

<!--T:19-->
*[[Special:MyLanguage/Constipation|Constipation]]
*Abdominal pain
*Abdominal cramps
*Abdominal distention
*Flatulence
*[[Special:MyLanguage/Dyspepsia|Dyspepsia]]
*Loose stool/[[Special:MyLanguage/Diarrhea|Diarrhea]]
*[[Special:MyLanguage/Nausea|Nausea]]/[[Special:MyLanguage/Vomiting|Vomiting]]
*ALT, AST elevation
*Alk Phos. elevation
*Bleeding [[Special:MyLanguage/hemorrhoids|hemorrhoids]]


==Pharmacology== <!--T:20-->

<!--T:21-->
*Half-life: Unknown
*Metabolism: N/A
*Excretion: Feces


==Mechanism of Action== <!--T:22-->

<!--T:23-->
Binds intestinal bile acids for excretion.


==Comments== <!--T:24-->


==See Also== <!--T:25-->

<!--T:26-->
[[Special:MyLanguage/Digoxin toxicity|Digoxin toxicity]]


==References== <!--T:27-->

<!--T:28-->
<references/>

<!--T:29-->
[[Category:Pharmacology]]
[[Category:GI]]
[[Category:Toxicology]]
</translate>