View source for Graft-vs-host disease

==Background==
*Acute vs Chronic
**Acute: 1-12 weeks post graft (<100 days)
**Chronic: >12 weeks
*Transplanted graft with immunologically competent cells stimulated by host antigens and host is incapable of mounting an effective immunologic response
*Occurs in leukemia/lymphoma or immunocompromised
**Most commonly post HSCT: [[Hematopoietic stem cell transplant]]
*Rare in solid organ transplant

==Clinical Features==
*Nonspecific [[rash]]
*Mucositis
*[[Fever]]
*[[Diarrhea]]

==Differential Diagnosis==
{{Transfusion reaction types}}

{{Transplant emergency types}}

==Evaluation==
*[[LFTs|LFT]] abnormalities
*[[Pancytopenia]]

==Management==
*Glucocorticoids

==Disposition==

==See Also==
*[[Transplant complications]]
{{Transfusion reactions see also}}

==External Links==

==References==
<references/>

[[Category:Heme/Onc]]