View source for Temazepam

==Administration==
*Type: [[Benzodiazepine]]
*Dosage Forms: Cap 7.5mg, 15mg, 22.5mg, 30mg
*Routes of Administration: Oral
*Common Trade Names: Restoril

==Adult Dosing==
===[[Insomnia]]===
*15mg PO qhs
**Start 7.5mg PO qhs in elderly patients
===Sleep terrors===
*15-30mg PO qhs

==Pediatric Dosing==
Safety/efficacy not established in pediatric patients

==Special Populations==
===[[Drug pregnancy categories|Pregnancy Rating]]===
*Consider alternatives during pregnancy
*Risk of neonatal withdrawal symptoms and floppy infant syndrome

===Lactation risk===
*May use low doses short-term when breastfeeding

===Renal Dosing===
*Adult: No adjustment
*Pediatric: Not defined

===Hepatic Dosing===
*Adult: No adjustment
*Pediatric: Not defined

==Contraindications==
*Allergy to class/drug
*Pregnancy
*Avoid abrupt withdrawal with long term use

==Adverse Reactions==
===Serious===
*[[Anaphylaxis]], [[angioedema]]
*Respiratory depression
*Dependency
*[[Seizure]]
*Suicidality
*[[Tachycardia]], [[hypotension]], [[syncope]]

===Common===
*Drowsiness, fatigue
*[[Dizziness]]
*[[Anxiety]], [[Amnesia]], confusion
*Disinhibition
*Dystonia. [[Dysarthria]], diplopia
*Incontinence, constipation
*[[Rash]]

==Pharmacology==
*Half-life: 8.8h
*Metabolism: Liver
*Excretion: Urine 80-90%

==Mechanism of Action==
*Binds to [[benzodiazepine]] receptors to enhance GABA effects

==Comments==


==See Also==
[[Benzodiazepine]]

==References==
<references/>

[[Category:Pharmacology]]