Amanita mushrooms - Revision history

Danbot: Add MedicationDose entries for N-acetylcysteine, penicillin G

2026-03-20T21:12:21Z

Add MedicationDose entries for N-acetylcysteine, penicillin G

@@ Line 73: / Line 73: @@
 *Prepare for liver transplant
 **Progressive [[coagulopathy]], [[encephalopathy]], renal failure are indications for transplant
 ==Disposition==

2024-03-27T22:01:48Z

Background

← Older revision		Revision as of 22:01, 27 March 2024
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	*''Amanita phalloides''		*''Amanita phalloides''
	*Not to be confused with ''Amanita muscaria''		*Not to be confused with ''Amanita muscaria''

			{{Anticholinergic types}}

	==Clinical Features==		==Clinical Features==

2024-03-27T22:01:09Z

2022-12-07T21:25:46Z

← Older revision		Revision as of 21:25, 7 December 2022
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	==Background==		==Background==
			[[File:Amanita phalloides.png\|thumb\|''Amanita phalloides'' aka "death cap"]]
	*''Amanita phalloides''		*''Amanita phalloides''
	*Not to be confused with ''Amanita muscaria''		*Not to be confused with ''Amanita muscaria''

	~~[[File:Amanita phalloides.png\|thumb\|Amanita phalloides aka death cap]]~~

	==Clinical Features==		==Clinical Features==

2022-12-07T21:24:49Z

Immediate therapy

← Older revision		Revision as of 21:24, 7 December 2022
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	*[[Penicillin]]		*[[Penicillin]]
	**High doses 1 mil units/kg/d effective in animal studies (inhibits amatoxin uptake)		**High doses 1 mil units/kg/d effective in animal studies (inhibits amatoxin uptake)
	*[[Silibinin]] (milk thistle derivative)		*Silibinin (milk thistle derivative)
	**'''Mortality benefit'''		**'''Mortality benefit'''
	**Free radical scavenger used successfully in Europe		**Free radical scavenger used successfully in Europe

2022-12-07T21:24:33Z

Evaluation

← Older revision		Revision as of 21:24, 7 December 2022
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	*Urine drug screen		*Urine drug screen
	*[[Urinalysis]]		*[[Urinalysis]]

			===Diagnosis===
			*Typically based on history and laboratory findings

	==Management==		==Management==

2022-12-07T21:17:44Z

Stage 3 (failure)

← Older revision		Revision as of 21:17, 7 December 2022
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	===Stage 3 (failure)===		===Stage 3 (failure)===
	*Occurs 2-4d after ingestion		*Occurs 2-4 days after ingestion
	*Fulminant [[liver failure]]		*Fulminant [[liver failure]]
	**[[Hyperbilirubinemia]], [[coagulopathy]], [[hepatic encephalopathy]], [[hepatorenal syndrome]]		**[[Hyperbilirubinemia]], [[coagulopathy]], [[hepatic encephalopathy]], [[hepatorenal syndrome]]
	*Death may occur in ~~three to seven~~ days.		*Death (may occur in 3-7 days)

	==Differential Diagnosis==		==Differential Diagnosis==

2022-11-24T13:17:31Z

Stage 3 (failure)

← Older revision		Revision as of 13:17, 24 November 2022
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	*Fulminant [[liver failure]]		*Fulminant [[liver failure]]
	**[[Hyperbilirubinemia]], [[coagulopathy]], [[hepatic encephalopathy]], [[hepatorenal syndrome]]		**[[Hyperbilirubinemia]], [[coagulopathy]], [[hepatic encephalopathy]], [[hepatorenal syndrome]]
			*Death may occur in three to seven days.

	==Differential Diagnosis==		==Differential Diagnosis==

2021-02-06T01:14:41Z

Background

← Older revision		Revision as of 01:14, 6 February 2021
Line 1:		Line 1:
	==Background==		==Background==
	''Amanita phalloides''		*''Amanita phalloides''
			*Not to be confused with ''Amanita muscaria''

	[[File:Amanita phalloides.png\|thumb\|Amanita phalloides aka death cap]]		[[File:Amanita phalloides.png\|thumb\|Amanita phalloides aka death cap]]

2019-01-30T15:35:13Z

← Older revision		Revision as of 15:35, 30 January 2019
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	*The later the onset of symptoms the better the outcome		*The later the onset of symptoms the better the outcome
	*GI predominant symptoms:		*GI predominant symptoms:
	**Abdominal pain, vomiting and diarrhea (which may become bloody)		**[[Abdominal pain]], [[vomiting]] and [[diarrhea]] (which may become bloody)

	===Stage 2 (convalescent)===		===Stage 2 (convalescent)===
Line 17:		Line 17:
	===Stage 3 (failure)===		===Stage 3 (failure)===
	*Occurs 2-4d after ingestion		*Occurs 2-4d after ingestion
	*Fulminant liver failure		*Fulminant [[liver failure]]
	**Hyperbilirubinemia, coagulopathy, hepatic encephalopathy, hepatorenal syndrome		**[[Hyperbilirubinemia]], [[coagulopathy]], [[hepatic encephalopathy]], [[hepatorenal syndrome]]

	==Differential Diagnosis==		==Differential Diagnosis==
Line 29:		Line 29:
	*Blood sugar		*Blood sugar
	*BMP		*BMP
	*~~LFT~~		*[[LFTs]]
	*Lipase		*Lipase
	*Coags, DIC labs		*Coags, [[DIC]] labs
	*CBC with differential		*CBC with differential
	*LDH, haptoglobin, reticulocyte		*LDH, haptoglobin, reticulocyte
	*CK		*CK
	*Thyroid studies		*Thyroid studies
	*Methemoglobin level		*[[Methemoglobin]] level
	*Urine drug screen		*Urine drug screen
	*[[Urinalysis]]		*[[Urinalysis]]