Cefditoren - Revision history

Ostermayer at 16:20, 18 July 2025

2025-07-18T16:20:22Z

← Older revision		Revision as of 16:20, 18 July 2025
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	==General==		==General==
	*Type: ~~Third~~ generation [[Is DrugClass::cephalosporin]]		*Type: [[Is Generation::3rd generation]] [[Is DrugClass::cephalosporin]]
	*Dosage Forms: tablet		*Dosage Forms: tablet
	*Dosage Strengths: 200, 400mg		*Dosage Strengths: 200, 400mg

Ostermayer at 14:49, 18 July 2025

2025-07-18T14:49:09Z

← Older revision		Revision as of 14:49, 18 July 2025
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	==General==		==General==
	*Type: Third generation [[cephalosporin]]		*Type: Third generation [[Is DrugClass::cephalosporin]]
	*Dosage Forms: tablet		*Dosage Forms: tablet
	*Dosage Strengths: 200, 400mg		*Dosage Strengths: 200, 400mg

ClaireLewis at 21:48, 19 September 2019

2019-09-19T21:48:40Z

← Older revision		Revision as of 21:48, 19 September 2019
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	<references/>		<references/>

	[[Category:Pharmacology]]		[[Category:Pharmacology]] [[Category:ID]]

Humanguy: edited dosage forms, strengths, routes of administration

2017-10-12T01:00:01Z

edited dosage forms, strengths, routes of administration

← Older revision		Revision as of 01:00, 12 October 2017
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	==General==		==General==
	*Type: Third generation [[cephalosporin]]		*Type: Third generation [[cephalosporin]]
	*Dosage Forms: ~~Tablet~~ 200,~~400 mg~~		*Dosage Forms: tablet
			*Dosage Strengths: 200, 400mg
			*Routes of Administration: PO
	*Common Trade Names: Spectracef		*Common Trade Names: Spectracef

Mholtz at 23:09, 30 August 2017

2017-08-30T23:09:50Z

← Older revision		Revision as of 23:09, 30 August 2017
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	*[[Antibiotics (Main)]]		*[[Antibiotics (Main)]]

	==~~Source~~==		==References==
			<references/>

	~~<references/>~~
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Jonwarren: Inserted drug information and dosing

2017-08-15T20:55:38Z

Inserted drug information and dosing

← Older revision		Revision as of 20:55, 15 August 2017
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	==General==		==General==
	*Type: Third generation [[cephalosporin]]		*Type: Third generation [[cephalosporin]]
	*Dosage Forms:		*Dosage Forms: Tablet 200,400 mg
	*Common Trade Names:		*Common Trade Names: Spectracef

	==Adult Dosing==		==Adult Dosing==
			===Chronic [[Bronchitis]], Acute bacterial exacerbation===
			*400 mg PO bid x10 days
			===[[Pneumonia]], community-acquired===
			*400 mg PO bid for at least 5 days
			**May D/C after five days if afebrile x48-72 hours
			===[[Pharyngitis]]/Tonsillitis, streptococcal===
			*200mg PO bid x10 days
			===Skin infection===
			*200 mg PO bid x10 days

	==Pediatric Dosing==		==Pediatric Dosing==
			===12+ yo, Chronic [[Bronchitis]], Acute bacterial exacerbation===
			*400 mg PO bid x10 days
			===12+ yo, [[Pneumonia]], community-acquired===
			*400 mg PO bid x14 days
			===12+ yo, [[Pharyngitis]]/Tonsillitis, streptococcal===
			*200mg PO bid x10 days
			===12+ yo, Skin infection===
			*200 mg PO bid x10 days

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: B; May use during pregnancy
	*Lactation:		*Lactation: May use while breastfeeding
	*Renal Dosing		*Renal Dosing
	**Adult		**Adult
			***CrCl 30-49: Max 200mg bid
			***CrCl <30: Max 200mg qd
			***ESRD/HD: Not defined
	**Pediatric		**Pediatric
			***CrCl 30-49: Max 200mg bid
			***CrCl <30: Max 200mg qd
			***ESRD/HD: Not defined
	*Hepatic Dosing		*Hepatic Dosing
	**Adult		**Adult
			***Child-Pugh Class A or B: No adjusment
			***Child-Pugh Class C: Not defined
	**Pediatric		**Pediatric
			***Child-Pugh Class A or B: No adjusment
			***Child-Pugh Class C: Not defined

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
			*Hypersensitivity to milk proteins
			*Carnitine deficiency
			*Caution:
			**Hypersensitivity to PCN
			**Renal impairment
			**Decreased muscle mass
			**Recent abx-associated colitis

	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
			*[[Anaphylaxis]]
			*Serum-sickness like reaction
			*[[Stevens-Johnson syndrome]]
			*[[Erythema multiforme]]
			*[[Toxic epidermal necrolysis]]
			*[[Leukopenia]]
			*[[Neutropenia]]
			*[[Thrombocytopenia]]
			*[[Anemia]], hemolytic
			*[[Seizure]]
			*Nephrotoxicity
			*Cholestatic [[jaundice]]
			*C. difficle-associated diarrhea
			*Super infection
			*Carnitine deficiency (long-term use)

	===Common===		===Common===
			*[[Diarrhea]]
			*[[Nausea]]
			*[[Headache]]
			*[[Abdominal pain]]
			*Candidiasis, vulvovaginal
			*Dyspepsia

	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: 1.6h; 4.7h in severe renal impairment
	*Metabolism:		*Metabolism: Minimal
	*Excretion:		*Excretion: Urine primarily
	*Mechanism of Action:		*Mechanism of Action: Bactericidal; inhibits cell wall mucopeptide synthesis

	==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==		==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==

Ostermayer: Text replacement - "Category:Drugs" to "Category:Pharmacology"

2016-03-22T15:53:48Z

Text replacement - "Category:Drugs" to "Category:Pharmacology"

← Older revision		Revision as of 15:53, 22 March 2016
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	<references/>		<references/>
	[[Category:~~Drugs~~]]		[[Category:Pharmacology]]

Rossdonaldson1: /* See Also */

2015-01-20T05:49:00Z

Rossdonaldson1: /* General */

2015-01-20T05:48:42Z

General

← Older revision		Revision as of 05:48, 20 January 2015
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	==General==		==General==
	*Type:		*Type: Third generation [[cephalosporin]]
	*Dosage Forms:		*Dosage Forms:
	*Common Trade Names:		*Common Trade Names:

	==Adult Dosing==		==Adult Dosing==

Rossdonaldson1 at 00:33, 19 September 2014

2014-09-19T00:33:24Z

← Older revision		Revision as of 00:33, 19 September 2014
Line 159:		Line 159:

	<references/>		<references/>
			[[Category:Drugs]]

← Older revision		Revision as of 05:49, 20 January 2015
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	==See Also==		==See Also==
			*[[Antibiotics (Main)]]

	==Source==		==Source==