Crimean-Congo hemorrhagic fever - Revision history

Neil.m.young: Text replacement - "==Diagnostic Evaluation==" to "==Evaluation=="

2016-07-28T04:03:20Z

Text replacement - "==Diagnostic Evaluation==" to "==Evaluation=="

← Older revision		Revision as of 04:03, 28 July 2016
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	{{Fever in Traveler DDX}}		{{Fever in Traveler DDX}}

	==~~Diagnostic~~ Evaluation==		==Evaluation==
	*Antigen-capture ELISA		*Antigen-capture ELISA
	*RT-PCR		*RT-PCR

Ostermayer: Text replacement - "Category:TropMed" to "Category:Tropical Medicine"

2016-03-22T16:59:04Z

Text replacement - "Category:TropMed" to "Category:Tropical Medicine"

← Older revision		Revision as of 16:59, 22 March 2016
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	[[Category:ID]]		[[Category:ID]]
	[[Category:~~TropMed~~]]		[[Category:Tropical Medicine]]

Mholtz at 07:34, 7 September 2015

2015-09-07T07:34:36Z

← Older revision		Revision as of 07:34, 7 September 2015
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	==Background==		==Background==
	*A tick-borne virus (Nairovirus) in the Bunyavirus family		*Caused by tick-borne virus (Nairovirus) in the Bunyavirus family
	*Regions: Eastern Europe, Mediterranean, NW China, central Asia, southern Europe, Africa, Middle East, Indian subcontinent
	*Ixodid ticks are reservoir and vector; direct transmission via body fluids
	*First described in the Crimea and later in the Congo		*First described in the Crimea and later in the Congo
			*Affected regions: Eastern Europe, Mediterranean, NW China, central Asia, southern Europe, Africa, Middle East, Indian subcontinent
			*Ixodid ticks are reservoir and vector
			*Direct human-human transmission via body fluids

	==Clinical Features==		==Clinical Features==
Line 24:		Line 25:
	{{Fever in Traveler DDX}}		{{Fever in Traveler DDX}}

	==~~Diagnosis~~==		==Diagnostic Evaluation==
	~~'''Labs''':~~
	*Antigen-capture ELISA		*Antigen-capture ELISA
	*RT-PCR		*RT-PCR
	*Virus isolation		*Virus isolation
	*Antibody ELISA		*Antibody ELISA

	~~'''Imaging''':~~
	~~None~~

	==Management==		==Management==
	*Supportive		*Supportive care
	*IV/PO Ribavirin		*IV/PO Ribavirin

	==Disposition==		==Disposition==
	~~Admission~~		*Admit

	==See Also==		==See Also==
	[[Viral hemorrhagic fevers]]		*[[Viral hemorrhagic fevers]]

			==External Links==
			*[http://www.cdc.gov/vhf/crimean-congo/ CDC Crimean-Congo Hemorrhagic Fever]

	==References==		==References==
	*Crimean-Congo Hemorrhagic Fever (CCHF). www.cdc.gov. [http://www.cdc.gov/vhf/crimean-congo/]. Updated [5/9/15].
	*Crimean-Congo Hemorrhagic Fever (CCHF). World Health Organization Fact Sheet. [http://www.who.int/mediacentre/factsheets/fs208/en/].
	*Rosen's Emergency Medicine. 8e. 2013.
	<references/>		<references/>

	[[Category:ID]]		[[Category:ID]]
			[[Category:TropMed]]

Rossdonaldson1 at 07:25, 31 August 2015

2015-08-31T07:25:24Z

← Older revision		Revision as of 07:25, 31 August 2015
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	==See Also==		==See Also==
	[[Viral hemorrhagic fevers]]		[[Viral hemorrhagic fevers]]

	~~==Category==~~
	~~[[Infectious Disease]]~~

	==References==		==References==
	*Crimean-Congo Hemorrhagic Fever (CCHF). www.cdc.gov. [http://www.cdc.gov/vhf/crimean-congo/]. Updated [5/9/15].		*Crimean-Congo Hemorrhagic Fever (CCHF). www.cdc.gov. [http://www.cdc.gov/vhf/crimean-congo/]. Updated [5/9/15].
	~~<references/>~~
	*Crimean-Congo Hemorrhagic Fever (CCHF). World Health Organization Fact Sheet. [http://www.who.int/mediacentre/factsheets/fs208/en/].		*Crimean-Congo Hemorrhagic Fever (CCHF). World Health Organization Fact Sheet. [http://www.who.int/mediacentre/factsheets/fs208/en/].
	~~<references/>~~
	*Rosen's Emergency Medicine. 8e. 2013.		*Rosen's Emergency Medicine. 8e. 2013.
	<references/>		<references/>

			[[Category:ID]]

Rossdonaldson1: /* Differential Diagnosis */

2015-08-31T07:24:21Z

Differential Diagnosis

← Older revision		Revision as of 07:24, 31 August 2015
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	==Differential Diagnosis==		==Differential Diagnosis==
	~~Other etiologies of viral hemorrhagic fever~~		{{Fever in Traveler DDX}}

	==Diagnosis==		==Diagnosis==

Mary Billington: added external links (references)

2015-08-30T20:21:12Z

added external links (references)

New page

==Background==
*A tick-borne virus (Nairovirus) in the Bunyavirus family
*Regions: Eastern Europe, Mediterranean, NW China, central Asia, southern Europe, Africa, Middle East, Indian subcontinent
*Ixodid ticks are reservoir and vector; direct transmission via body fluids
*First described in the Crimea and later in the Congo

==Clinical Features==
'''History''':
*Exposure risk factors: animal herders, livestock workers, slaughterhouse workers, and healthcare workers in endemic areas
*Incubation period usually lasts less than one week from exposure
*Sudden onset of: headache, high fever, back/joint/stomach pain, vomiting, photophobia
*Mood swing and confusion develop after initial symptoms, followed by sleepiness and depression.
*Abdominal pain migrates to RUQ

'''Physical Exam''':
*Conjunctivitis, facial flushing, palatal erythema and petechiae, lymphadenopathy,
*Jaundice and changes in mood and sensory perception
*Signs of coagulopathy (starting around day 4)
*Palpable hepatomegaly

'''Clinical Course''': Estimated 9-50% mortality

==Differential Diagnosis==
Other etiologies of viral hemorrhagic fever

==Diagnosis==
'''Labs''':
*Antigen-capture ELISA
*RT-PCR
*Virus isolation
*Antibody ELISA

'''Imaging''':
None

==Management==
*Supportive
*IV/PO Ribavirin

==Disposition==
Admission

==See Also==
[[Viral hemorrhagic fevers]]

==Category==
[[Infectious Disease]]

==References==
*Crimean-Congo Hemorrhagic Fever (CCHF). www.cdc.gov. [http://www.cdc.gov/vhf/crimean-congo/]. Updated [5/9/15].
<references/>
*Crimean-Congo Hemorrhagic Fever (CCHF). World Health Organization Fact Sheet. [http://www.who.int/mediacentre/factsheets/fs208/en/].
<references/>
*Rosen's Emergency Medicine. 8e. 2013.
<references/>