Cutaneous larva migrans - Revision history

Rossdonaldson1 at 12:38, 12 December 2020

2020-12-12T12:38:20Z

← Older revision		Revision as of 12:38, 12 December 2020
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	**History is typically of a patient sunbathing, walking on the beach, etc in a tropical environment<ref name="Vano-Galvan">Vano-Galvan S, Gil-Mosquera M, Truchuelo M, Jaén P. Cutaneous larva migrans: a case report. Cases Journal. 2009;2:112. doi:10.1186/1757-1626-2-112.</ref>		**History is typically of a patient sunbathing, walking on the beach, etc in a tropical environment<ref name="Vano-Galvan">Vano-Galvan S, Gil-Mosquera M, Truchuelo M, Jaén P. Cutaneous larva migrans: a case report. Cases Journal. 2009;2:112. doi:10.1186/1757-1626-2-112.</ref>

			==Clinical Features==
	[[File:LarvaMigrans2.png\|thumb\|CLM on thigh of child]]		[[File:LarvaMigrans2.png\|thumb\|CLM on thigh of child]]
	[[File:LarvaMigrans.png\|thumb\|CLM on leg of 32y/o M]]		[[File:LarvaMigrans.png\|thumb\|CLM on leg of 32y/o M]]

	~~==Clinical Features==~~
	*[[Pruritus\|Pruritic]], serpiginous eruption<ref name="Prickett" />		*[[Pruritus\|Pruritic]], serpiginous eruption<ref name="Prickett" />
	**Pruritus can be severe and intractable<ref name="Vano-Galvan" />, and can lead to impaired sleep and mood disturbance<ref name="Kincaid">Kincaid L, Klowak M, Klowak S, Boggild AK. Management of imported cutaneous larva migrans: A case series and mini-review. Travel Med Infect Dis. 2015 Jul 29.</ref>		**Pruritus can be severe and intractable<ref name="Vano-Galvan" />, and can lead to impaired sleep and mood disturbance<ref name="Kincaid">Kincaid L, Klowak M, Klowak S, Boggild AK. Management of imported cutaneous larva migrans: A case series and mini-review. Travel Med Infect Dis. 2015 Jul 29.</ref>

ClaireLewis at 20:44, 27 September 2019

2019-09-27T20:44:27Z

← Older revision		Revision as of 20:44, 27 September 2019
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	==Clinical Features==		==Clinical Features==
	*~~Pruritis~~ serpiginous eruption<ref name="Prickett" />		*[[Pruritus\|Pruritic]], serpiginous eruption<ref name="Prickett" />
	**~~Pruritis~~ can be severe and intractable<ref name="Vano-Galvan" />, and can lead to impaired sleep and mood disturbance<ref name="Kincaid">Kincaid L, Klowak M, Klowak S, Boggild AK. Management of imported cutaneous larva migrans: A case series and mini-review. Travel Med Infect Dis. 2015 Jul 29.</ref>		**Pruritus can be severe and intractable<ref name="Vano-Galvan" />, and can lead to impaired sleep and mood disturbance<ref name="Kincaid">Kincaid L, Klowak M, Klowak S, Boggild AK. Management of imported cutaneous larva migrans: A case series and mini-review. Travel Med Infect Dis. 2015 Jul 29.</ref>
	**Usually unilateral, but can be bilateral		**Usually unilateral, but can be bilateral
	**Linear, moving lesions		**Linear, moving lesions
	**Hand, feet, buttock most commonly affected. <ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>		**Hand, feet, buttock most commonly affected. <ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>

			==Complications==
			*Loeffler's Syndrome<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>
			**Respiratory symptoms, pulmonary infiltrates, and peripheral [[eosinophilia]].
			**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.
			**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.

	==Differential Diagnosis==		==Differential Diagnosis==
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	*Self-limited condition - larvae die within 2-8 weeks<ref name="Prickett" />		*Self-limited condition - larvae die within 2-8 weeks<ref name="Prickett" />
	**Goal of treatment is to relieve severe pruritus		**Goal of treatment is to relieve severe pruritus
	*First Line: ivermectin 200ug/kg, single dose. <ref>Feldmeier H, Schuster A. Mini-review: Hookwarm-related cutaneous larva migrans. Eur J Clin Microbiol Infect Dis (2012) 31:915-918</ref>		*First Line: [[ivermectin]] 200ug/kg, single dose. <ref>Feldmeier H, Schuster A. Mini-review: Hookwarm-related cutaneous larva migrans. Eur J Clin Microbiol Infect Dis (2012) 31:915-918</ref>
	**Alternatives: Albendazole 400mg orally for 5 to 7days OR Topical tiabendazole 10-15% TID for 5 to 7days		**Alternatives: [[Albendazole]] 400mg orally for 5 to 7days OR Topical tiabendazole 10-15% TID for 5 to 7days
	*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />		*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />

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	*Discharge		*Discharge

	~~==Complications==~~
	*Loeffler's Syndrome<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>
	**Respiratory symptoms, pulmonary infiltrates, and peripheral eosinophilia.
	**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.
	**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.

	==See Also==		==See Also==

Rossdonaldson1 at 12:39, 14 March 2018

2018-03-14T12:39:31Z

← Older revision		Revision as of 12:39, 14 March 2018
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	*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />		*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />

	==~~Rare~~ Complications==		==Disposition==
			*Discharge

			==Complications==
	*Loeffler's Syndrome<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>		*Loeffler's Syndrome<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>
	**Respiratory symptoms, pulmonary infiltrates, and peripheral eosinophilia.		**Respiratory symptoms, pulmonary infiltrates, and peripheral eosinophilia.
	**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.		**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.
	**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.		**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.

	~~==Disposition==~~
	*Discharge

	==See Also==		==See Also==

Rossdonaldson1: /* Rare Complications */

2018-03-14T12:38:57Z

Rare Complications

← Older revision		Revision as of 12:38, 14 March 2018
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	==Rare Complications==		==Rare Complications==
	*Loeffler's Syndrome		*Loeffler's Syndrome<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>
	**Respiratory symptoms, pulmonary infiltrates, and peripheral eosinophilia.		**Respiratory symptoms, pulmonary infiltrates, and peripheral eosinophilia.
	**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.		**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.
	**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.		**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.
	~~<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>~~

	==Disposition==		==Disposition==

Pascualj: /* Clinical Features */

2018-02-22T16:16:17Z

Clinical Features

← Older revision		Revision as of 16:16, 22 February 2018
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	**''Ancylostoma caninum'' and ''Ancylostoma braziliense'' are most common pathogens		**''Ancylostoma caninum'' and ''Ancylostoma braziliense'' are most common pathogens
	**Typically occurs due to contact with dog/cat feces in soil/sand		**Typically occurs due to contact with dog/cat feces in soil/sand
	**More common in warm/tropical areas		**More common in warm/tropical areas, particularly during rainy season
	**History is typically of a patient sunbathing, walking on the beach, etc in a tropical environment<ref name="Vano-Galvan">Vano-Galvan S, Gil-Mosquera M, Truchuelo M, Jaén P. Cutaneous larva migrans: a case report. Cases Journal. 2009;2:112. doi:10.1186/1757-1626-2-112.</ref>		**History is typically of a patient sunbathing, walking on the beach, etc in a tropical environment<ref name="Vano-Galvan">Vano-Galvan S, Gil-Mosquera M, Truchuelo M, Jaén P. Cutaneous larva migrans: a case report. Cases Journal. 2009;2:112. doi:10.1186/1757-1626-2-112.</ref>

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	**Usually unilateral, but can be bilateral		**Usually unilateral, but can be bilateral
	**Linear, moving lesions		**Linear, moving lesions
			**Hand, feet, buttock most commonly affected. <ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>

	==Differential Diagnosis==		==Differential Diagnosis==
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	*Self-limited condition - larvae die within 2-8 weeks<ref name="Prickett" />		*Self-limited condition - larvae die within 2-8 weeks<ref name="Prickett" />
	**Goal of treatment is to relieve severe pruritus		**Goal of treatment is to relieve severe pruritus
	*Albendazole 400mg ~~PO QD x3-~~5 ~~days '''~~OR~~''' Ivermectin 12mg PO x1 '''OR''' topical thiabendazole~~ TID ~~x15 days~~		*First Line: ivermectin 200ug/kg, single dose. <ref>Feldmeier H, Schuster A. Mini-review: Hookwarm-related cutaneous larva migrans. Eur J Clin Microbiol Infect Dis (2012) 31:915-918</ref>
			**Alternatives: Albendazole 400mg orally for 5 to 7days OR Topical tiabendazole 10-15% TID for 5 to 7days
	*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />		*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />

			==Rare Complications==
			*Loeffler's Syndrome
			**Respiratory symptoms, pulmonary infiltrates, and peripheral eosinophilia.
			**Believed by some to be a systemic immune reaction to the parasite but exact pathogenesis unknown.
			**Treatment: treating parasitic infection leads to resolution of the pulmonary symptoms.
			<ref>Pascual J, Laoteppitaks C. Unique Rash after Beach Vacation. Journal of Emergency Medicine. 2017 June;52(6):878-879. Epub 2017 April 8</ref>

	==Disposition==		==Disposition==

Aganapathy: /* Clinical Features */

2018-01-28T08:52:03Z

Clinical Features

← Older revision		Revision as of 08:52, 28 January 2018
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	**Pruritis can be severe and intractable<ref name="Vano-Galvan" />, and can lead to impaired sleep and mood disturbance<ref name="Kincaid">Kincaid L, Klowak M, Klowak S, Boggild AK. Management of imported cutaneous larva migrans: A case series and mini-review. Travel Med Infect Dis. 2015 Jul 29.</ref>		**Pruritis can be severe and intractable<ref name="Vano-Galvan" />, and can lead to impaired sleep and mood disturbance<ref name="Kincaid">Kincaid L, Klowak M, Klowak S, Boggild AK. Management of imported cutaneous larva migrans: A case series and mini-review. Travel Med Infect Dis. 2015 Jul 29.</ref>
	**Usually unilateral, but can be bilateral		**Usually unilateral, but can be bilateral
			**Linear, moving lesions

	==Differential Diagnosis==		==Differential Diagnosis==

Neil.m.young: Text replacement - "pruritis" to "pruritus"

2016-10-27T16:10:57Z

Text replacement - "pruritis" to "pruritus"

← Older revision		Revision as of 16:10, 27 October 2016
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	==Management==		==Management==
	*Self-limited condition - larvae die within 2-8 weeks<ref name="Prickett" />		*Self-limited condition - larvae die within 2-8 weeks<ref name="Prickett" />
	**Goal of treatment is to relieve severe ~~pruritis~~		**Goal of treatment is to relieve severe pruritus
	*Albendazole 400mg PO QD x3-5 days '''OR''' Ivermectin 12mg PO x1 '''OR''' topical thiabendazole TID x15 days		*Albendazole 400mg PO QD x3-5 days '''OR''' Ivermectin 12mg PO x1 '''OR''' topical thiabendazole TID x15 days
	*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />		*Mebendazole has poor oral bioavailability and does not work for cutaneous larva migrans<ref name="Kincaid" />

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-23T16:09:42Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Older revision		Revision as of 16:09, 23 July 2016
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	{{Travel Skin Conditions DDX}}		{{Travel Skin Conditions DDX}}

	==~~Diagnosis~~==		==Evaluation==
	*Clinical diagnosis, based on history and physical exam		*Clinical diagnosis, based on history and physical exam

Ostermayer: Text replacement - "Category:TropMed" to "Category:Tropical Medicine"

2016-03-22T16:59:19Z

Text replacement - "Category:TropMed" to "Category:Tropical Medicine"

← Older revision		Revision as of 16:59, 22 March 2016
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	[[Category:Dermatology]]		[[Category:Dermatology]]
	[[Category:ID]]		[[Category:ID]]
	[[Category:~~TropMed~~]]		[[Category:Tropical Medicine]]

Ostermayer: Text replacement - "Category:Derm" to "Category:Dermatology"

2016-03-22T13:13:44Z

Text replacement - "Category:Derm" to "Category:Dermatology"

← Older revision		Revision as of 13:13, 22 March 2016
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	<references/>		<references/>

	[[Category:~~Derm~~]]		[[Category:Dermatology]]
	[[Category:ID]]		[[Category:ID]]
	[[Category:TropMed]]		[[Category:TropMed]]