Droperidol - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:56:22Z

Switch SMW query from broadtable to table format for better layout with TOC

← Older revision		Revision as of 21:56, 20 March 2026
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	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T17:24:24Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

← Older revision		Revision as of 17:24, 20 March 2026
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	\|format=broadtable		\|format=broadtable
	\|headers=plain		\|headers=plain
	\|~~link~~=~~subject~~		\|mainlabel=-
	\|sort=Has Indication		\|sort=Has Indication
	\|limit=50		\|limit=50

Danbot: Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

2026-03-20T16:42:32Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

← Older revision		Revision as of 16:42, 20 March 2026
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	==Comments==		==Comments==


			==Indications by Condition==
			''The following table is automatically generated from disease/condition pages across WikEM.''

			{{#ask:[[Has DrugName::Droperidol]]
			\|?Has Indication=Indication
			\|?Has Dose=Dose
			\|?Has Context=Context
			\|?Has Route=Route
			\|?Has Population=Population
			\|format=broadtable
			\|headers=plain
			\|link=subject
			\|sort=Has Indication
			\|limit=50
			}}

	==See Also==		==See Also==

Rossdonaldson1: /* Pediatric Dosing */

2021-10-06T17:01:19Z

Pediatric Dosing

← Older revision		Revision as of 17:01, 6 October 2021
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	==Pediatric Dosing==		==Pediatric Dosing==
	===[[Nausea/vomiting]]===		===[[Nausea and vomiting (peds)\|Nausea/vomiting]]===
	*2-12yo: 0.015-0.1mg/kg IV/IM		*2-12yo: 0.015-0.1mg/kg IV/IM

Rossdonaldson1: /* Pain (with or without opiate tolerance) */

2021-10-06T16:59:19Z

Pain (with or without opiate tolerance)

← Older revision		Revision as of 16:59, 6 October 2021
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	===[[Headache]]===		===[[Headache]]===
	*2.5mg IV or 2.5-5mg IM		*2.5mg IV or 2.5-5mg IM
	===[[Pain (with or without opiate tolerance)]]===		===Pain (with or without opiate tolerance)===
	*0.625-5mg or higher IV/IM<ref>Richards JR, Richards IN, Ozery G, Derlet RW. Droperidol analgesia for opioid-tolerant patients. J Emerg Med. 2011 Oct;41(4):389-96. doi: 10.1016/j.jemermed.2010.07.005. Epub 2010 Sep 15. PMID: 20832967.</ref><ref>Miller AC, Khan AM, Castro Bigalli AA, Sewell KA, King AR, Ghadermarzi S, Mao Y, Zehtabchi S. Neuroleptanalgesia for acute abdominal pain: a systematic review. J Pain Res. 2019;12:787-801 https://doi.org/10.2147/JPR.S187798</ref>		*0.625-5mg or higher IV/IM<ref>Richards JR, Richards IN, Ozery G, Derlet RW. Droperidol analgesia for opioid-tolerant patients. J Emerg Med. 2011 Oct;41(4):389-96. doi: 10.1016/j.jemermed.2010.07.005. Epub 2010 Sep 15. PMID: 20832967.</ref><ref>Miller AC, Khan AM, Castro Bigalli AA, Sewell KA, King AR, Ghadermarzi S, Mao Y, Zehtabchi S. Neuroleptanalgesia for acute abdominal pain: a systematic review. J Pain Res. 2019;12:787-801 https://doi.org/10.2147/JPR.S187798</ref>

Rossdonaldson1 at 16:58, 6 October 2021

2021-10-06T16:58:44Z

← Older revision		Revision as of 16:58, 6 October 2021
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	===Common===		===Common===
	*Somnolence, dysphoria, anxiety		*Somnolence, dysphoria, anxiety
	*~~'''~~Akathisia~~''': restlessness, inability to sit still, distressing disquiet~~		*[[Akathisia]]
	**Treatable with diphenhydramine (50mg PO/IM/IV) OR benztropine (1-2mg IV) and others<ref>Pringsheim T, Gardner D, Addington D, et al. The Assessment and Treatment of Antipsychotic-Induced Akathisia. Can J Psychiatry. 2018;63(11):719-729. doi:10.1177/0706743718760288</ref><ref>Rice, J. CoreEM.net - Akathisia. https://coreem.net/core/akathisia/ Accessed: Oct 4, 2021.</ref>
	*Hypotension		*Hypotension
	*Tachycardia		*Tachycardia
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	==Comments==		==Comments==
	In my experience akathisia and dystonia are more common in women up to about 30 years old and teenagers of both sexes. I don't use it on anyone younger than 18. Also, there seems to be an association with rate of administration and side-effects. When I order it, I have the nurses put the dose in a 10mL saline flush and give it over a minute. Anecdotally, this seems to decrease the rate of side-effects. When they occur, 50 mg diphenhydramine IVP is my go-to medication, which usually works, though I have had to redose.

	~~It is VERY useful as an adjunct to other pain medications, opiates or otherwise, when you are reaching your comfort level for those meds.~~

	~~It is far superior to ondansetron for intractable vomiting, especially cannabinoid hyperemesis syndrome, which some readers will use droperidol's sister drug, haloperidol, to treat.~~

	==See Also==		==See Also==

Corkeith: /* Common */

2021-10-05T18:50:41Z

Common

← Older revision		Revision as of 18:50, 5 October 2021
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	*5-10mg IV		*5-10mg IV
	*10mg IM		*10mg IM
			===[[Nausea/vomiting]]===
			*0.625-2.5mg IV
	===[[Headache]]===		===[[Headache]]===
	*2.5mg IV or 2.5-5mg IM		*2.5mg IV or 2.5-5mg IM
	===[[~~Nausea/vomiting~~]]===		===[[Pain (with or without opiate tolerance)]]===
	*0.625-2.5mg IV		*0.625-5mg or higher IV/IM<ref>Richards JR, Richards IN, Ozery G, Derlet RW. Droperidol analgesia for opioid-tolerant patients. J Emerg Med. 2011 Oct;41(4):389-96. doi: 10.1016/j.jemermed.2010.07.005. Epub 2010 Sep 15. PMID: 20832967.</ref><ref>Miller AC, Khan AM, Castro Bigalli AA, Sewell KA, King AR, Ghadermarzi S, Mao Y, Zehtabchi S. Neuroleptanalgesia for acute abdominal pain: a systematic review. J Pain Res. 2019;12:787-801 https://doi.org/10.2147/JPR.S187798</ref>

	==Pediatric Dosing==		==Pediatric Dosing==
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	===Common===		===Common===
	*Somnolence, dysphoria		*Somnolence, dysphoria, anxiety
	*~~Anxiety~~, ~~restlessness~~, ~~hyperactivity~~		*'''Akathisia''': restlessness, inability to sit still, distressing disquiet
			**Treatable with diphenhydramine (50mg PO/IM/IV) OR benztropine (1-2mg IV) and others<ref>Pringsheim T, Gardner D, Addington D, et al. The Assessment and Treatment of Antipsychotic-Induced Akathisia. Can J Psychiatry. 2018;63(11):719-729. doi:10.1177/0706743718760288</ref><ref>Rice, J. CoreEM.net - Akathisia. https://coreem.net/core/akathisia/ Accessed: Oct 4, 2021.</ref>
	*Hypotension		*Hypotension
	*Tachycardia		*Tachycardia
Line 53:		Line 55:

	==Comments==		==Comments==
			In my experience akathisia and dystonia are more common in women up to about 30 years old and teenagers of both sexes. I don't use it on anyone younger than 18. Also, there seems to be an association with rate of administration and side-effects. When I order it, I have the nurses put the dose in a 10mL saline flush and give it over a minute. Anecdotally, this seems to decrease the rate of side-effects. When they occur, 50 mg diphenhydramine IVP is my go-to medication, which usually works, though I have had to redose.

			It is VERY useful as an adjunct to other pain medications, opiates or otherwise, when you are reaching your comfort level for those meds.

			It is far superior to ondansetron for intractable vomiting, especially cannabinoid hyperemesis syndrome, which some readers will use droperidol's sister drug, haloperidol, to treat.

	==See Also==		==See Also==
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	==External Links==		==External Links==
	*[http://www.emdocs.net/droperidol-use-in-the-emergency-department-whats-old-is-new-again/ emDOCs: Droperidol Use in the Emergency Department – What’s Old is New Again]		*[http://www.emdocs.net/droperidol-use-in-the-emergency-department-whats-old-is-new-again/ emDOCs: Droperidol Use in the Emergency Department – What’s Old is New Again]
	*[https://www.acep.org/~~how-we-serve~~/~~sections~~/~~pain-management/news/may-2020~~/oldie-but-a-goodie-10-pearls-of-droperidol/ ACEP: Oldie but a Goodie: 10 Pearls of Droperidol]		*[https://www.acep.org/painmanagement/newsroom/may2020/oldie-but-a-goodie-10-pearls-of-droperidol/ ACEP: Oldie but a Goodie: 10 Pearls of Droperidol]

	==References==		==References==

Elcatracho: /* External Links */

2021-03-14T22:24:27Z

External Links

← Older revision		Revision as of 22:24, 14 March 2021
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	==External Links==		==External Links==
	*[http://www.emdocs.net/droperidol-use-in-the-emergency-department-whats-old-is-new-again/ emDOCs: Droperidol Use in the Emergency Department – What’s Old is New Again]		*[http://www.emdocs.net/droperidol-use-in-the-emergency-department-whats-old-is-new-again/ emDOCs: Droperidol Use in the Emergency Department – What’s Old is New Again]
			*[https://www.acep.org/how-we-serve/sections/pain-management/news/may-2020/oldie-but-a-goodie-10-pearls-of-droperidol/ ACEP: Oldie but a Goodie: 10 Pearls of Droperidol]

	==References==		==References==

Elcatracho: /* See Also */

2021-03-13T23:08:37Z

Elcatracho: /* Adverse Reactions */

2021-03-13T23:06:32Z

Adverse Reactions

← Older revision		Revision as of 23:06, 13 March 2021
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*[[Prolonged QT]], torsades, ventricular tachycardia, cardiac arrest		*[[Prolonged QT]], [[torsades]], [[ventricular tachycardia]], [[cardiac arrest]]
	**''Note: effect on QT interval is dose-dependent''		**''Note: effect on QT interval is dose-dependent''
	**In 2001, FDA gave black box warning for risk of [[torsades de pointes]], however this ~~was not supported by literature~~		**In 2001, FDA gave black box warning for risk of [[torsades de pointes]], however there was little evidence to support this
	**Large cohort of patients in ED showed safety of its administration<ref>Gaw CM, Cabrera D, Bellolio F, Mattson AE, Lohse CM, Jeffery MM. Effectiveness and safety of droperidol in a United States emergency department. Am J Emerg Med. 2020;38(7):1310-1314. doi:10.1016/j.ajem.2019.09.007</ref>		**Large cohort of patients in ED showed safety of its administration<ref>Gaw CM, Cabrera D, Bellolio F, Mattson AE, Lohse CM, Jeffery MM. Effectiveness and safety of droperidol in a United States emergency department. Am J Emerg Med. 2020;38(7):1310-1314. doi:10.1016/j.ajem.2019.09.007</ref>
	*Neuroleptic malignant syndrome		*[[Neuroleptic malignant syndrome]]
	*Anaphylaxis		*[[Anaphylaxis]]

	===Common===		===Common===

← Older revision		Revision as of 23:08, 13 March 2021
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	*[[Antipsychotics]]		*[[Antipsychotics]]
	*[[Combative patient]]		*[[Combative patient]]

			==External Links==
			*[http://www.emdocs.net/droperidol-use-in-the-emergency-department-whats-old-is-new-again/ emDOCs: Droperidol Use in the Emergency Department – What’s Old is New Again]

	==References==		==References==