https://wikem.org/w/index.php?action=history&feed=atom&title=EphedrineEphedrine - Revision history2026-04-18T08:07:48ZRevision history for this page on the wikiMediaWiki 1.38.2https://wikem.org/w/index.php?title=Ephedrine&diff=204379&oldid=prevClaireLewis: Created page with "==Administration== *Type: Sympathomimetic, Pressors *Dosage Forms: *Routes of Administration: IV; ephedrine directly from ''ephedra'' plant may be consumed PO as compo..."2019-01-27T20:19:12Z<p>Created page with "==Administration== *Type: <a href="/wiki/Sympathomimetic" class="mw-redirect" title="Sympathomimetic">Sympathomimetic</a>, <a href="/wiki/Pressors" class="mw-redirect" title="Pressors">Pressors</a> *Dosage Forms: *Routes of Administration: IV; ephedrine directly from ''ephedra'' plant may be consumed PO as compo..."</p>
<p><b>New page</b></p><div>==Administration==<br />
*Type: [[Sympathomimetic]], [[Pressors]]<br />
*Dosage Forms:<br />
*Routes of Administration: IV; ephedrine directly from ''ephedra'' plant may be consumed PO as component of traditional chinese medicine<br />
*Common Trade Names: <br />
<br />
==Adult Dosing==<br />
*Hypotension in setting of analgesia: 5-10mg IV bolus, repeat prn, max dose 50mg<br />
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==Pediatric Dosing==<br />
'''Safety/efficacy not established'''<br />
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==Special Populations==<br />
===[[Drug pregnancy categories|Pregnancy Rating]]===<br />
*Fetal risk cannot be ruled out<br />
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===Lactation risk===<br />
*Infant risk cannot be ruled out<br />
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===Renal Dosing===<br />
*Adult: not established<br />
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===Hepatic Dosing===<br />
*Adult: Not established<br />
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==Contraindications==<br />
*Allergy to class/drug<br />
*Closed angle [[glaucoma]], [[Pheochromocytoma]] <ref>https://www.nps.org.au/medical-info/medicine-finder/dbl-ephedrine-sulfate-solution-for-injection#side-effects</ref><br />
*Caution if using postpartum with concomitant oxytocics<br />
*Caution in severe hypertension, history of cardiac disease<br />
*Caution with concomitant use of norepi-dopa reuptake inhibitors (e.g. [[bupropion]], Ritalin)<br />
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==Adverse Reactions==<br />
===Serious===<br />
*Severe hypertension<br />
*[[Stroke]]<br />
*[[Tachycardia]], [[bradycardia]]<br />
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===Common===<br />
*[[Hypertension]]<br />
*[[Palpitations]], [[Tachycardia]]<br />
*[[Nausea/vomiting]]<br />
*[[Dizziness]], restlessness<br />
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==Pharmacology==<br />
*Half-life: 6h<br />
*Metabolism: <br />
*Excretion: Renal<br />
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==Mechanism of Action==<br />
*Sympathomimetic: stimulates both alpha and beta adrenergic receptors<br />
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==Comments==<br />
*Ephedrine in its natural plant form, known as ''má huáng'' (麻黄), used in traditional chinese medicine as decongestant, bronchodilator<br />
*Ephedrine used historically (now illicitly) for weight-loss and recreationally as stimulant due to its' [[amphetamine]]-like properties<br />
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==See Also==<br />
*[[Sympathomimetic]]<br />
*[[Pressors]]<br />
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==References==<br />
<references/><br />
<br />
[[Category:Pharmacology]]</div>ClaireLewis