Etomidate - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:57:58Z

Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T17:25:02Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T16:43:09Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

@@ Line 55: / Line 55: @@
 *Excretion: Urine
 *Mechanism of Action: GABA agonist
 ==See Also==

2024-06-13T01:39:23Z

Controversy

← Older revision		Revision as of 01:39, 13 June 2024
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	* apnea		* apnea
	===Controversy===		===Controversy===
	"The available evidence suggests that etomidate suppresses adrenal function transiently without		*May suppress adrenal function in critically ill patient
			**"The available evidence suggests that etomidate suppresses adrenal function transiently without
	demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality."<ref>*Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113.</ref>		demonstrating a significant effect on mortality. However, no studies to date have been powered to detect a difference in hospital, ventilator, or ICU length of stay or in mortality."<ref>*Hohl CM, Kelly-Smith CH,Yeung TC, Sweet DD, Doyle-Waters MM, Schulzer M. The effect of a bolus dose of Etomidate on cortisol levels, mortality, and health services utilization: a systematic review. Ann Emerg Med. 2010;56(2):105-113.</ref>
			*Meta-analysis in 2023 showed increased mortality in critically ill patients

	==Pharmacology==		==Pharmacology==

2024-06-13T01:33:05Z

General

← Older revision		Revision as of 01:33, 13 June 2024
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	==General==		==General==
	*Type: [[Sedation\|Sedative]]		*Type: [[Sedation\|Sedative]]
	*Dosage Forms:		*Dosage Forms: IV
	*Common Trade Names: Amidate		*Common Trade Names: Amidate, Tomvi

	==Adult Dosing==		==Adult Dosing==

2024-06-13T01:28:16Z

Pediatric Dosing

← Older revision		Revision as of 01:28, 13 June 2024
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	==Pediatric Dosing==		==Pediatric Dosing==
	''See [[critical care quick reference]] for drug doses by weight.''		''See [[critical care quick reference]] for drug doses by weight.''

			*Children < 10 years
			**0.2-0.3 mg/kg IV
			*Children > 10 years
			**0.3 mg/kg IV

	==Special Populations==		==Special Populations==

2024-06-13T01:26:50Z

Adult Dosing

← Older revision		Revision as of 01:26, 13 June 2024
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	*0.3mg/kg bolus IV		*0.3mg/kg bolus IV
	*Average: 20mg		*Average: 20mg
	**Consider ~~halving does~~ for patients ~~in [[shock]]~~		**Consider half-dose (0.15mg/kg) for obtunded patients

	===[[Procedural Sedation]]===		===[[Procedural Sedation]]===

2021-05-13T16:42:58Z

← Older revision		Revision as of 16:42, 13 May 2021
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	===[[RSI]]===		===[[RSI]]===
	*0.3mg/kg bolus IV		*0.3mg/kg bolus IV
	*~~Standard dose =~~ 20mg		*Average: 20mg
			**Consider halving does for patients in [[shock]]

	===[[Procedural Sedation]]===		===[[Procedural Sedation]]===
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	==Pediatric Dosing==		==Pediatric Dosing==
	''See [[critical care quick reference]] for drug doses by weight.''		''See [[critical care quick reference]] for drug doses by weight.''
	~~==[[RSI]]==~~
	*0.3mg/kg bolus IV
	*Average: 20mg
	**Consider halving does for patients in [[shock]]

	~~==[[Procedural Sedation]]==~~
	~~{{procedure sedation etomidate}}~~

	==Special Populations==		==Special Populations==

2021-05-12T20:26:35Z

RSI

← Older revision		Revision as of 20:26, 12 May 2021
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	==[[RSI]]==		==[[RSI]]==
	*0.3mg/kg bolus IV		*0.3mg/kg bolus IV
	*~~Max~~: 20mg		*Average: 20mg
			**Consider halving does for patients in [[shock]]

	==[[Procedural Sedation]]==		==[[Procedural Sedation]]==

2021-02-21T03:11:57Z

General