Fludrocortisone - Revision history

Mholtz: Text replacement - "* " to "*"

2017-07-24T01:13:22Z

Text replacement - "* " to "*"

← Older revision		Revision as of 01:13, 24 July 2017
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	==Adult Dosing==		==Adult Dosing==
	* Adrenal Insufficiency		*Adrenal Insufficiency
	**0.1 mg 3 times per week to 0.2 mg daily. Give with food or milk. Taper dose gradually to d/c.		**0.1 mg 3 times per week to 0.2 mg daily. Give with food or milk. Taper dose gradually to d/c.
	* Orthostatic Hypotension		*Orthostatic Hypotension
	**0.1 mg PO qD initially then may increase by 0.1 mg/d weekly up to a max of 1 mg/d (>0.5 mg rarely helpful). Taper dose gradually to d/c.		**0.1 mg PO qD initially then may increase by 0.1 mg/d weekly up to a max of 1 mg/d (>0.5 mg rarely helpful). Taper dose gradually to d/c.

Heston at 19:41, 28 October 2016

2016-10-28T19:41:23Z

← Older revision		Revision as of 19:41, 28 October 2016
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	==Pharmacology==		==Pharmacology==
	*Half-life: 3.5 hours		*Half-life: 3.5 hours
	*Metabolism: Hepatic		*Metabolism: Hepatic, kidney
	*Excretion:		*Excretion: urine

	==Mechanism of Action==		==Mechanism of Action==

Heston at 19:34, 28 October 2016

2016-10-28T19:34:21Z

← Older revision		Revision as of 19:34, 28 October 2016
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	==Administration==		==Administration==
	*Type: [[Corticosteroid]]		*Type: [[Corticosteroid]]
	*Dosage Forms:		*Dosage Forms: 0.1 mg oral tablets
	*Routes of Administration: PO		*Routes of Administration: PO
	*Common Trade Names:		*Common Trade Names: Florinef (note: brand discontinued in US)

	==Adult Dosing==		==Adult Dosing==

Heston at 19:32, 28 October 2016

2016-10-28T19:32:37Z

← Older revision		Revision as of 19:32, 28 October 2016
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	==Adult Dosing==		==Adult Dosing==
	*0.1 mg 3 times per week to 0.2 mg daily		* Adrenal Insufficiency
			**0.1 mg 3 times per week to 0.2 mg daily. Give with food or milk. Taper dose gradually to d/c.
			* Orthostatic Hypotension
			**0.1 mg PO qD initially then may increase by 0.1 mg/d weekly up to a max of 1 mg/d (>0.5 mg rarely helpful). Taper dose gradually to d/c.

	==Pediatric Dosing==		==Pediatric Dosing==

ClaireLewis: /* Pediatric Dosing */

2016-10-05T08:48:41Z

Pediatric Dosing

← Older revision		Revision as of 08:48, 5 October 2016
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	==Pediatric Dosing==		==Pediatric Dosing==
	'''NOT FDA approved in children'''		''NOT FDA approved in children''
	*0.05-0.2 mg/day		*0.05-0.2 mg/day

ClaireLewis: Created page with "==Administration== Type: Corticosteroid Dosage Forms: Routes of Administration: PO Common Trade Names: ==Adult Dosing== *0.1 mg 3 times per week to 0.2 mg daily ==P..."

2016-10-05T08:48:26Z

Created page with "==Administration== *Type: Corticosteroid *Dosage Forms: *Routes of Administration: PO *Common Trade Names: ==Adult Dosing== *0.1 mg 3 times per week to 0.2 mg daily ==P..."

New page

==Administration==
*Type: [[Corticosteroid]]
*Dosage Forms:
*Routes of Administration: PO
*Common Trade Names:

==Adult Dosing==
*0.1 mg 3 times per week to 0.2 mg daily

==Pediatric Dosing==
'''NOT FDA approved in children'''
*0.05-0.2 mg/day

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C
*[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out
*Renal dosing: no adjustment
*Hepatic dosing: no adjustment

==Contraindications==
*Allergy to class/drug
*Systemic fungal infections

==Adverse Reactions==
===Serious===
*Secondary adrenal insufficiency
*Elevated ICP, seizure
*CHF, cardiomegaly, hypertension
*Thrombophlebitis
===Common===
*Bruising, petechiae
*Impaired wound healing
*Hyperglycemia, hypokalemia
*Rash, urticaria
*Peptic ulcer disease
*Irregular menses, growth delay (children)
*Headache, vertigo

==Pharmacology==
*Half-life: 3.5 hours
*Metabolism: Hepatic
*Excretion:

==Mechanism of Action==
*Very potent mineralocorticoid, also has glucocorticoid effects

==Comments==

==See Also==
*[[Corticosteroids]]
*[[Adrenal insufficiency]]

==References==
<references/>
[[Category:Pharmacology]]