Furosemide - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:56:43Z

Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T17:24:45Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T16:42:53Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

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 *Excretion: urine
 *Mechanism of Action: inhibits loop of henle and proximal and distal convoluted tubule sodium and chloride resorption
 ==See Also==

2020-05-16T04:06:35Z

Pediatric Dosing

2017-07-13T06:34:56Z

2017-01-15T21:04:00Z

Adult Dosing

← Older revision		Revision as of 21:04, 15 January 2017
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	==Adult Dosing==		==Adult Dosing==
	''40 mg [[furosemide]] = 20 mg [[torsemide]] = 1 mg [[bumetanide]]''		''40 mg [[furosemide]] = 20 mg [[torsemide]] = 1 mg [[bumetanide]] = 50 mg [[ethacrynic acid]]''
	*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV		*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV
	*[[hypertension]]: 10-40 mg PO QDAY-BID, max 600 mg/day		*[[hypertension]]: 10-40 mg PO QDAY-BID, max 600 mg/day

2016-12-22T16:45:02Z

← Older revision		Revision as of 16:45, 22 December 2016
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	==Adult Dosing==		==Adult Dosing==
	''~~40mg~~ [[furosemide]] = ~~20mg~~ [[torsemide]] = ~~1mg~~ [[bumetanide]]''		''40 mg [[furosemide]] = 20 mg [[torsemide]] = 1 mg [[bumetanide]]''
	*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV		*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV
	*[[hypertension]]: 10-~~40mg~~ PO QDAY-BID, max ~~600mg~~/day		*[[hypertension]]: 10-40 mg PO QDAY-BID, max 600 mg/day
	*[[Hypercalcemia]]: ~~120mg~~/day PO divided QDAY - TID		*[[Hypercalcemia]]: 120 mg/day PO divided QDAY - TID
			*Continuous infusion may increase diuresis effect and minimize post-diuretic sodium retention and "diuretic braking"<ref>Pivac N, Rumboldt Z, Sardelic S et al. Diuretic effects of furosemide infusion versus bolus injection in congestive heart failure. Int J Clin Pharmacol Res. 1998; 18:121–8.</ref>
			**Start 0.1 mg/kg/hr, increase hourly to max of 0.75 mg/kg/hr<ref>Schuller D, Lynch JP, Fine D. Protocol-guided diuretic management: comparison of furosemide by continuous infusion and intermittent bolus. Crit Care Med. 1997; 25:1969–75.</ref>
			**Target > 1 mL/kg/hr
			**Monitor for ototoxicity

	==Pediatric Dosing==		==Pediatric Dosing==

2016-12-22T16:33:07Z

← Older revision		Revision as of 16:33, 22 December 2016
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	==Adult Dosing==		==Adult Dosing==
			''40mg [[furosemide]] = 20mg [[torsemide]] = 1mg [[bumetanide]]''
	*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV		*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV
	*[[hypertension]]: 10-40mg PO QDAY-BID, max 600mg/day		*[[hypertension]]: 10-40mg PO QDAY-BID, max 600mg/day

2016-12-22T16:32:29Z

← Older revision		Revision as of 16:32, 22 December 2016
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	*Dosage Forms:20, 40, 80		*Dosage Forms:20, 40, 80
	*Common Trade Names: Lasix		*Common Trade Names: Lasix
			*Approximately 50% bioavailability, so converting from oral to IV dose doubles oral dose<ref>Asare K. Management of Loop Diuretic Resistance in the Intensive Care Unit. Am J Health Syst Pharm. 2009;66(18):1635-1640.</ref>
			*Furosemide absorption may be reduced in decompensated [[CHF]]<ref>Vasko MR, Brown-Cartwright D, Knochel JP et al. Furosemide absorption is altered in decompensated congestive heart failure. Ann Intern Med. 1985; 102: 314–8.</ref>

	==Adult Dosing==		==Adult Dosing==

2016-09-24T09:13:45Z

← Older revision		Revision as of 09:13, 24 September 2016
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	==Adult Dosing==		==Adult Dosing==
	*hypertension: 10-40mg PO QDAY-BID, max 600mg/day		*[[Fluid overload]]: Typically 40 mg IV or normal PO dosage IV
	*Hypercalcemia: 120mg/day PO divided QDAY - TID		*[[hypertension]]: 10-40mg PO QDAY-BID, max 600mg/day
			*[[Hypercalcemia]]: 120mg/day PO divided QDAY - TID

	==Pediatric Dosing==		==Pediatric Dosing==
	*Hypercalcemia: 25-50mg IV q4h		*[[Hypercalcemia]]: 25-50mg IV q4h

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:C		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:C