Gentamicin - Revision history

Danbot: Remove disease-specific entries now covered by AntibioticDose (1 sections)

2026-03-20T11:07:54Z

Remove disease-specific entries now covered by AntibioticDose (1 sections)

← Older revision		Revision as of 11:07, 20 March 2026
Line 15:		Line 15:
	**1-1.7mg/kg IM/IV q8h		**1-1.7mg/kg IM/IV q8h

	~~===Uncomplicated [[Gonococcal]]===~~
	*240mg IM x 1

	===Indications by Disease===		===Indications by Disease===

Danbot: Remove disease-specific dosing covered by dynamic SMW tables

2026-03-20T02:57:23Z

Remove disease-specific dosing covered by dynamic SMW tables

← Older revision		Revision as of 02:57, 20 March 2026
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	===Uncomplicated [[Gonococcal]]===		===Uncomplicated [[Gonococcal]]===
	*240mg IM x 1		*240mg IM x 1

	~~===Severe [[PID]]===~~
	*1.5mg/kg IM/IV q8h
	**Start 2mg/kg IM/IV x 1
	*Alt: 3-5mg/kg IM/IV q24h
	*Info: Give with [[clindamycin]]


	===Indications by Disease===		===Indications by Disease===

Danbot: Restore original dosing content alongside dynamic SMW tables

2026-03-20T02:37:23Z

Restore original dosing content alongside dynamic SMW tables

@@ Line 5: / Line 5: @@
 ==Adult Dosing==
 ===Indications by Disease===
 {{#ask: [[Has DrugName::Gentamicin]] [[Has Population::Adult]]
-|?Treats disease=Disease
+ |?Treats disease=Disease
-|?Has Dose=Dose
+ |?Has Dose=Dose
-|?Has Context=Context
+ |?Has Context=Context
-|format=table
+ |format=table
-|limit=50
+ |limit=50
-|mainlabel=-
+ |mainlabel=-
-|headers=show
+ |headers=show
-|sort=Treats disease
+ |sort=Treats disease
 }}
 ==Pediatric Dosing==
 ===Indications by Disease===
 {{#ask: [[Has DrugName::Gentamicin]] [[Has Population::Pediatric]]
-|?Treats disease=Disease
+ |?Treats disease=Disease
-|?Has Dose=Dose
+ |?Has Dose=Dose
-|?Has Context=Context
+ |?Has Context=Context
-|format=table
+ |format=table
-|limit=50
+ |limit=50
-|mainlabel=-
+ |mainlabel=-
-|headers=show
+ |headers=show
-|sort=Treats disease
+ |sort=Treats disease
 }}

Danbot: Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

2026-03-20T01:51:49Z

Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

← Older revision		Revision as of 01:51, 20 March 2026
Line 5:		Line 5:

	==Adult Dosing==		==Adult Dosing==
	*'''All: If obese, use Adjusted Weight = ~~IBW + 0.4 x (ABW - IBW)~~		===Indications by Disease===
	*'''All: Adjust repeat dosing based on levels'''		{{#ask: [[Has DrugName::Gentamicin]] [[Has Population::Adult]]
			\|?Treats disease=Disease
	==~~=General~~===		\|?Has Dose=Dose
	*Extended Interval		\|?Has Context=Context
	**5-7mg/kg IV q24h		\|format=table
	**First Dose: ~~5-7mg/kg IV~~		\|limit=50
	*Conventional		\|mainlabel=-
	**1-1.7mg/kg IM/IV q8h		\|headers=show
			\|sort=Treats disease
	~~===Uncomplicated~~ [[~~Gonococcal~~]]~~===~~		}}
	*240mg IM x 1

	~~===Severe~~ [[~~PID~~]]===
	*1.5mg/kg IM/IV q8h
	**Start 2mg/kg IM/IV x 1
	*Alt: 3-~~5mg/kg IM/IV q24h~~
	*Info: Give with [[clindamycin]]

	==Pediatric Dosing==		==Pediatric Dosing==
	*'''All: adjust repeat dosing based on levels'''		===Indications by Disease===
			{{#ask: [[Has DrugName::Gentamicin]] [[Has Population::Pediatric]]
	===~~General (<8 Days Old)~~===		\|?Treats disease=Disease
	*'''First Dose All: ~~2.5mg/kg IV/IM x1'''~~		\|?Has Dose=Dose
	*<28 weeks gestation		\|?Has Context=Context
	**2.5mg/kg IV/IM q24h		\|format=table
	**Alt: ~~5mg/kg IV/IM q48h~~		\|limit=50
	*28-29 weeks gestation		\|mainlabel=-
	**2.5mg/kg IV/IM q18h		\|headers=show
	**Alt: ~~5mg/kg IV/IM q48h~~		\|sort=Treats disease
	*30-33 weeks gestation		}}
	**2.5mg/kg IV/IM q18h
	**Alt 1: ~~3.5mg/kg IV/IM q24hr~~
	**Alt 2: ~~4.5mg/kg IV/IM q36-48h~~
	*34 weeks gestation
	**2.5mg/kg IV/IM q18h
	**Alt 1: 3.5mg/kg IV/IM q24hr
	**Alt 2: 4mg/kg IV/IM q24-36h
	*35-36 weeks gestation
	**2.5mg/kg IV/IM q 12h
	**Alt 1: 3.5mg/kg IV/IM q24
	**Alt 2: 4mg/kg IV/IM q24-36h
	*Full Term
	**2.5mg/kg IV/IM q12h
	**Alt: 4mg/kg IV/IM q24h

	~~===General (8 Days - 1 Month)==~~=
	*'''First Dose ~~All: 2.5mg/kg IV/IM x1'''~~
	*<30 weeks gestation
	**2.5mg/kg IV/IM q18h
	**Alt: 4mg/kg IV/IM q24-36h
	*30-33 weeks gestation
	**2.5mg/kg IV/IM q12h
	**Alt: 4mg/kg IV/IM q24
	*34 weeks gestation
	**2.5mg/kg IV/IM q12h
	**Alt: 4mg/kg IV/IM q18h
	*35-~~36 weeks gestation~~
	**2.5mg/kg IV/IM q8h
	**Alt: 4mg/kg IV/IM q12h
	*Full term
	**2.5mg/kg IV/IM q8h
	**Alt: 4mg/kg IV/IM q24h

	=~~==General (1 Month -6 Months)===~~
	*2.5mg/kg IV/IM q8h
	*Alt: 6.5mg/kg IV/IM q24h

	===~~General (>6 Months)===~~
	*2.5mg/kg IV/IM
	*Alt: 6.5-7.5mg/kg IV/IM q24h
	*Use IBW if >2yo

	==Special Populations==		==Special Populations==

Ostermayer: /* Antibiotic SensitivitiesSanford Guide to Antimicrobial Therapy 2014 */

2025-07-18T18:23:47Z

Antibiotic SensitivitiesSanford Guide to Antimicrobial Therapy 2014

← Older revision		Revision as of 18:23, 18 July 2025
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	\| \|\|[[Acinetobacter sp.]]\|\|R		\| \|\|[[Acinetobacter sp.]]\|\|R
	\|-		\|-
	\| \|\|[[Pseudomonas aeruginosa]]\|\|'''S'''		\| \|\|[[Pseudomonas aeruginosa]]\|\|'''[[Has Antipseudomonal::S]]'''
	\|-		\|-
	\| \|\|[[Burkholderia cepacia]]\|\|R		\| \|\|[[Burkholderia cepacia]]\|\|R

Ostermayer at 15:13, 18 July 2025

2025-07-18T15:13:02Z

← Older revision		Revision as of 15:13, 18 July 2025
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	==General==		==General==
	*Type: [[~~Aminoglycosides~~]]		*Type: [[Is DrugClass::Aminoglycoside]]
	*Dosage Forms: IM; IV		*Dosage Forms: IM; IV
	*Common Trade Names: Genticyn, Garamycin, Gentak		*Common Trade Names: Genticyn, Garamycin, Gentak

Blsimpso: /* General */

2022-10-01T18:43:09Z

General

← Older revision		Revision as of 18:43, 1 October 2022
Line 2:		Line 2:
	*Type: [[Aminoglycosides]]		*Type: [[Aminoglycosides]]
	*Dosage Forms: IM; IV		*Dosage Forms: IM; IV
	*Common Trade Names:		*Common Trade Names: Genticyn, Garamycin, Gentak

	==Adult Dosing==		==Adult Dosing==

Blsimpso: /* Adverse Reactions */

2022-10-01T18:39:40Z

Adverse Reactions

← Older revision		Revision as of 18:39, 1 October 2022
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
			*Ototoxicity<ref>https://www.drugs.com/monograph/gentamicin-systemic.html</ref>
			*Nephrotoxicity
			*Prolongation of neuromuscular blockers

	===Common===		===Common===
			*Nausea/vomiting
			*Irritation at injection site

	==Pharmacology==		==Pharmacology==

Blsimpso: /* Pharmacology */

2022-10-01T18:32:06Z

Pharmacology

← Older revision		Revision as of 18:32, 1 October 2022
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	*Metabolism:		*Metabolism:
	*Excretion: Urine excretion		*Excretion: Urine excretion
	*Mechanism of Action:		*Mechanism of Action: Binds to 30S and 50S ribosomal subunits, disrupting mRNA translation and interfering with bacterial protein synthesis<ref>Chaves BJ, Tadi P. Gentamicin. [Updated 2022 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557550/</ref>

	==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==		==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==

Blsimpso: /* Pharmacology */

2022-10-01T18:28:25Z

Pharmacology

← Older revision		Revision as of 18:28, 1 October 2022
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	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life:2-3 hours
	*Metabolism:		*Metabolism:
	*Excretion:		*Excretion: Urine excretion
	*Mechanism of Action:		*Mechanism of Action: