Hemochromatosis - Revision history

Rossdonaldson1: /* See Also */

2022-09-07T22:37:59Z

Rossdonaldson1: /* Clinical Features */

2022-09-07T22:15:45Z

Clinical Features

← Older revision		Revision as of 22:15, 7 September 2022
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	*AKA "bronze diabetes"		*AKA "bronze diabetes"
	==Clinical Features==		==Clinical Features==
			[[File:PMC4006333 CHSJ-40-1-067-fig3.png\|thumb\|Abdomen enlargement caused by giant hepatomegaly occupying the entire abdomen in a patient with secondary hemochromatosis.]]
	*[[Cirrhosis]]		*[[Cirrhosis]]
	*[[Diabetes]] due to iron deposition in pancreatic beta cells		*[[Diabetes]] due to iron deposition in pancreatic beta cells
	*[[Cardiomyopathy]]		*[[Cardiomyopathy]]
	*[[Arthritis]]: knuckles of the second and third fingers most common		*[[Arthritis]]: knuckles of the second and third fingers most common
	*Bronzing of the skin		*Bronzing of the skin

	==Differential Diagnosis==		==Differential Diagnosis==
	{{Hepatomegaly DDX}}		{{Hepatomegaly DDX}}

Rossdonaldson1: /* Differential Diagnosis */

2022-09-07T22:06:18Z

Differential Diagnosis

← Older revision		Revision as of 22:06, 7 September 2022
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	*Bronzing of the skin		*Bronzing of the skin
	==Differential Diagnosis==		==Differential Diagnosis==
			{{Hepatomegaly DDX}}
	{{Hyperglycemia DDX}}		{{Hyperglycemia DDX}}

Kfarzam: /* Evaluation */

2022-08-18T07:13:27Z

Evaluation

← Older revision		Revision as of 07:13, 18 August 2022
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	**>300 ng/mL in males and postmenopausal women		**>300 ng/mL in males and postmenopausal women
	**>150 - 200 ng/mL in premenopausal women		**>150 - 200 ng/mL in premenopausal women
			*Transferrin saturation: >45-50% is suggestive of iron overload
			*Outpatient HFE genetic test to confirm diagnosis

	==Management==		==Management==
	*Phlebotomy		*Phlebotomy

Rossdonaldson1: /* Differential Diagnosis */

2018-11-10T04:54:48Z

Differential Diagnosis

← Older revision		Revision as of 04:54, 10 November 2018
Line 11:		Line 11:
	*Bronzing of the skin		*Bronzing of the skin
	==Differential Diagnosis==		==Differential Diagnosis==
			{{Hyperglycemia DDX}}

	==Evaluation==		==Evaluation==

Mholtz: Text replacement - "* " to "*"

2017-07-24T01:13:32Z

Text replacement - "* " to "*"

← Older revision		Revision as of 01:13, 24 July 2017
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	*[[Diabetes]] due to iron deposition in pancreatic beta cells		*[[Diabetes]] due to iron deposition in pancreatic beta cells
	*[[Cardiomyopathy]]		*[[Cardiomyopathy]]
	* [[Arthritis]]: knuckles of the second and third fingers most common		*[[Arthritis]]: knuckles of the second and third fingers most common
	* Bronzing of the skin		*Bronzing of the skin
	==Differential Diagnosis==		==Differential Diagnosis==

	==Evaluation==		==Evaluation==
	*Serum ferritin:		*Serum ferritin:
	** >300 ng/mL in males and postmenopausal women		**>300 ng/mL in males and postmenopausal women
	** >150 - 200 ng/mL in premenopausal women		**>150 - 200 ng/mL in premenopausal women
	==Management==		==Management==
	*Phlebotomy		*Phlebotomy

ClaireLewis at 18:02, 27 March 2017

2017-03-27T18:02:03Z

← Older revision		Revision as of 18:02, 27 March 2017
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	==Background==		==Background==
	*~~accumulation~~ of iron in the body		*Accumulation of iron in the body
	*~~most~~ commonly due to hereditary hemochromatosis (HHC) ~~and transfusional~~ iron overload		*Most commonly due to hereditary hemochromatosis (HHC) or iron overload from [[transfusion]]
	**Hereditary hemochromatosis most common in people of Celtic ancestry		**Hereditary hemochromatosis most common in people of Celtic ancestry
	*AKA "bronze diabetes"		*AKA "bronze diabetes"
Line 18:		Line 18:
	==Management==		==Management==
	*Phlebotomy		*Phlebotomy
	*Chelation with deferoxamine		*Chelation with [[deferoxamine]]
	==Disposition==		==Disposition==

Line 27:		Line 27:
	==References==		==References==
	<references/>		<references/>

			[[Category:Heme/Onc]]

Unenthusiastic: Created page with "==Background== accumulation of iron in the body most commonly due to hereditary hemochromatosis (HHC) and transfusional iron overload **Hereditary hemochromatosis most commo..."

2017-03-18T21:49:08Z

Created page with "==Background== *accumulation of iron in the body *most commonly due to hereditary hemochromatosis (HHC) and transfusional iron overload **Hereditary hemochromatosis most commo..."

New page

==Background==
*accumulation of iron in the body
*most commonly due to hereditary hemochromatosis (HHC) and transfusional iron overload
**Hereditary hemochromatosis most common in people of Celtic ancestry
*AKA "bronze diabetes"
==Clinical Features==
*[[Cirrhosis]]
*[[Diabetes]] due to iron deposition in pancreatic beta cells
*[[Cardiomyopathy]]
* [[Arthritis]]: knuckles of the second and third fingers most common
* Bronzing of the skin
==Differential Diagnosis==

==Evaluation==
*Serum ferritin:
** >300 ng/mL in males and postmenopausal women
** >150 - 200 ng/mL in premenopausal women
==Management==
*Phlebotomy
*Chelation with deferoxamine
==Disposition==

==See Also==

==External Links==

==References==
<references/>

← Older revision		Revision as of 22:37, 7 September 2022
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	==See Also==		==See Also==
			*[[Iron toxicity]]

	==External Links==		==External Links==

Hemochromatosis - Revision history

Rossdonaldson1: /* See Also */

Rossdonaldson1: /* Clinical Features */

Rossdonaldson1: /* Differential Diagnosis */

Kfarzam: /* Evaluation */

Rossdonaldson1: /* Differential Diagnosis */

Mholtz: Text replacement - "* " to "*"

ClaireLewis at 18:02, 27 March 2017

Unenthusiastic: Created page with "==Background== *accumulation of iron in the body *most commonly due to hereditary hemochromatosis (HHC) and transfusional iron overload **Hereditary hemochromatosis most commo..."

Unenthusiastic: Created page with "==Background== accumulation of iron in the body most commonly due to hereditary hemochromatosis (HHC) and transfusional iron overload **Hereditary hemochromatosis most commo..."