Intravascular hemolytic transfusion reaction - Revision history

Rossdonaldson1 at 17:45, 17 April 2024

2024-04-17T17:45:32Z

← Older revision		Revision as of 17:45, 17 April 2024
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	*Treat coagulopathy with [[FFP]]		*Treat coagulopathy with [[FFP]]
	*Consider IV [[methylprednisolone]]		*Consider IV [[methylprednisolone]]
	*Contact ICU

	==Disposition==		==Disposition==
			*Admission
			**Most frequently to ICU

	==See Also==		==See Also==

Rossdonaldson1: /* Management */

2024-04-17T17:44:59Z

Management

← Older revision		Revision as of 17:44, 17 April 2024
Line 25:		Line 25:
	*Treat shock with volume and [[vasopressors]]		*Treat shock with volume and [[vasopressors]]
	*Treat coagulopathy with [[FFP]]		*Treat coagulopathy with [[FFP]]
	*Consider IV methylprednisolone		*Consider IV [[methylprednisolone]]
	*Contact ICU		*Contact ICU

Beren85: /* Management */

2024-04-16T22:13:12Z

Management

← Older revision		Revision as of 22:13, 16 April 2024
Line 25:		Line 25:
	*Treat shock with volume and [[vasopressors]]		*Treat shock with volume and [[vasopressors]]
	*Treat coagulopathy with [[FFP]]		*Treat coagulopathy with [[FFP]]
			*Consider IV methylprednisolone
			*Contact ICU

	==Disposition==		==Disposition==

ClaireLewis at 01:05, 1 October 2019

2019-10-01T01:05:58Z

← Older revision		Revision as of 01:05, 1 October 2019
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	==Clinical Features==		==Clinical Features==
	*High grade [[fever]], [[back pain\|back]]/[[flank pain]], [[headache]], [[hypotension]], [[dyspnea]], [[pulmonary edema]], bleeding, [[renal failure]], [[hematuria]]		*High grade [[fever]], [[back pain\|back]]/[[flank pain]], [[headache]], [[hypotension]], [[dyspnea]], [[pulmonary edema]], [[coagulopathy\|bleeding]], [[renal failure]], [[hematuria]]
	*Sick and [[shock]]y		*Sick and [[shock]]y

ClaireLewis at 16:48, 17 September 2019

2019-09-17T16:48:16Z

← Older revision		Revision as of 16:48, 17 September 2019
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	==Clinical Features==		==Clinical Features==
	*High grade fever, back/flank pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure, hematuria		*High grade [[fever]], [[back pain\|back]]/[[flank pain]], [[headache]], [[hypotension]], [[dyspnea]], [[pulmonary edema]], bleeding, [[renal failure]], [[hematuria]]
	*Sick and ~~shocky~~		*Sick and [[shock]]y

	==Differential Diagnosis==		==Differential Diagnosis==
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	==Evaluation==		==Evaluation==
	*Labs consistent with hemolysis		*Labs consistent with [[hemolytic anemia\|hemolysis]]
	*Send off coombs test/direct antiglobin test		*Send off coombs test/direct antiglobin test
	**Coomb's reagent binds RBCs with Ab on them		**Coomb's reagent binds RBCs with Ab on them

ClaireLewis: Created page with "==Background== Occurs due to ABO incompatibility High mortality. 1:30 may die. ==Clinical Features== *High grade fever, back/flank pain, headache, hypotension, dyspnea, pul..."

2017-04-03T16:53:00Z

Created page with "==Background== *Occurs due to ABO incompatibility *High mortality. 1:30 may die. ==Clinical Features== *High grade fever, back/flank pain, headache, hypotension, dyspnea, pul..."

New page

==Background==
*Occurs due to ABO incompatibility
*High mortality. 1:30 may die.

==Clinical Features==
*High grade fever, back/flank pain, headache, hypotension, dyspnea, pulmonary edema, bleeding, renal failure, hematuria
*Sick and shocky

==Differential Diagnosis==
{{Transfusion reaction types}}

{{Acute Allergic DDX}}

==Evaluation==
*Labs consistent with hemolysis
*Send off coombs test/direct antiglobin test
**Coomb's reagent binds RBCs with Ab on them
[[File:Coombs.png|thumbnail]]

==Management==
*Stop transfusion
*Replace all tubing
**Risk of death is proportional to amount of incompatible blood received
*Maintain urine output with IVF (1-2 mL/kg/hr), [[mannitol]], and [[furosemide]] as needed
*Treat shock with volume and [[vasopressors]]
*Treat coagulopathy with [[FFP]]

==Disposition==

==See Also==
*[[Transfusion reaction]]

==External Links==

==References==
<references/>

[[Category:Heme/Onc]]