Metabolic dysfunction-associated steatohepatitis (MASH) - Revision history

Ostermayer: Prepared the page for translation

2026-01-04T23:46:31Z

Prepared the page for translation

← Older revision		Revision as of 23:46, 4 January 2026
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			<languages/>
			<translate>

	==Background==		==Background==
	*Formerly known as [[non-alcoholic steatohepatitis]]
			*Formerly known as [[Special:MyLanguage/non-alcoholic steatohepatitis\|non-alcoholic steatohepatitis]]
	[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]		[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
	[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]		[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]
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	[[File:Biliary system multilingual.png\|thumb\|Bile duct and pancreas anatomy. 1. Bile ducts: 2. Intrahepatic bile ducts; 3. Left and right hepatic ducts; 4. Common hepatic duct; 5. Cystic duct; 6. Common bile duct; 7. Sphincter of Oddi; 8. Major duodenal papilla; 9. Gallbladder; 10-11. Right and left lobes of liver; 12. Spleen; 13. Esophagus; 14. Stomach; 15. Pancreas: 16. Accessory pancreatic duct; 17. Pancreatic duct; 18. Small intestine; 19. Duodenum; 20. Jejunum; 21-22: Right and left kidneys.]]		[[File:Biliary system multilingual.png\|thumb\|Bile duct and pancreas anatomy. 1. Bile ducts: 2. Intrahepatic bile ducts; 3. Left and right hepatic ducts; 4. Common hepatic duct; 5. Cystic duct; 6. Common bile duct; 7. Sphincter of Oddi; 8. Major duodenal papilla; 9. Gallbladder; 10-11. Right and left lobes of liver; 12. Spleen; 13. Esophagus; 14. Stomach; 15. Pancreas: 16. Accessory pancreatic duct; 17. Pancreatic duct; 18. Small intestine; 19. Duodenum; 20. Jejunum; 21-22: Right and left kidneys.]]
	*Fatty liver disease due to causes other than excessive alcohol		*Fatty liver disease due to causes other than excessive alcohol
	*Associated with insulin resistance and [[metabolic syndrome]]		*Associated with insulin resistance and [[Special:MyLanguage/metabolic syndrome\|metabolic syndrome]]


	==Clinical Features==		==Clinical Features==
	*Often asymptomatic or with mild [[RUQ pain\|RUQ discomfort]]
	*Signs of portal hypertension (e.g. [[ascites]]) if advanced fibrosis		*Often asymptomatic or with mild [[Special:MyLanguage/RUQ pain\|RUQ discomfort]]
	*[[Hepatomegaly]]		*Signs of portal hypertension (e.g. [[Special:MyLanguage/ascites\|ascites]]) if advanced fibrosis
			*[[Special:MyLanguage/Hepatomegaly\|Hepatomegaly]]


	==Differential Diagnosis==		==Differential Diagnosis==

			</translate>
	{{Hepatomegaly DDX}}		{{Hepatomegaly DDX}}
			<translate>


	==Evaluation==		==Evaluation==
	*[[LFTs]], CBC
	*[[RUQ US]]		*[[Special:MyLanguage/LFTs\|LFTs]], CBC
			*[[Special:MyLanguage/RUQ US\|RUQ US]]
	*Outpatient elastography/Fibroscan		*Outpatient elastography/Fibroscan


	==Management==		==Management==

	*Treat complications of portal hypertension, if present		*Treat complications of portal hypertension, if present
	*Counsel on weight loss, increased coffee consumption		*Counsel on weight loss, increased coffee consumption
	*Vitamin E if known F2 fibrosis		*Vitamin E if known F2 fibrosis


	==Disposition==		==Disposition==

	*Discharge unless complications		*Discharge unless complications


	==See Also==		==See Also==
	*[[Hepatomegaly]]
			*[[Special:MyLanguage/Hepatomegaly\|Hepatomegaly]]


	==External Links==		==External Links==


	==References==		==References==

	<references/>		<references/>

	[[Category:GI]]		[[Category:GI]]
			</translate>

Ostermayer: /* Background */

2025-08-09T22:24:35Z

Background

← Older revision		Revision as of 22:24, 9 August 2025
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	==Background==		==Background==
	*Formerly known as [[non alcoholic steatohepatitis]]		*Formerly known as [[non-alcoholic steatohepatitis]]
	[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]		[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
	[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]		[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]

Ostermayer: /* Background */

2025-08-09T22:21:11Z

Background

← Older revision		Revision as of 22:21, 9 August 2025
Line 1:		Line 1:
	==Background==		==Background==
			*Formerly known as [[non alcoholic steatohepatitis]]
	[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]		[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
	[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]		[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]

Ostermayer: Ostermayer moved page Non-alcoholic steatohepatitis to Metabolic dysfunction-associated steatohepatitis (MASH): disease renaming

2025-08-09T22:18:21Z

Ostermayer moved page Non-alcoholic steatohepatitis to Metabolic dysfunction-associated steatohepatitis (MASH): disease renaming

← Older revision	Revision as of 22:18, 9 August 2025
(No difference)

Rossdonaldson1 at 23:12, 13 November 2024

2024-11-13T23:12:32Z

← Older revision		Revision as of 23:12, 13 November 2024
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	[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]		[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]
	[[File:Liver vascular anatomy.png\|thumb\|Liver vascular anatomy.]]		[[File:Liver vascular anatomy.png\|thumb\|Liver vascular anatomy.]]
			[[File:Biliary system multilingual.png\|thumb\|Bile duct and pancreas anatomy. 1. Bile ducts: 2. Intrahepatic bile ducts; 3. Left and right hepatic ducts; 4. Common hepatic duct; 5. Cystic duct; 6. Common bile duct; 7. Sphincter of Oddi; 8. Major duodenal papilla; 9. Gallbladder; 10-11. Right and left lobes of liver; 12. Spleen; 13. Esophagus; 14. Stomach; 15. Pancreas: 16. Accessory pancreatic duct; 17. Pancreatic duct; 18. Small intestine; 19. Duodenum; 20. Jejunum; 21-22: Right and left kidneys.]]
	*Fatty liver disease due to causes other than excessive alcohol		*Fatty liver disease due to causes other than excessive alcohol
	*Associated with insulin resistance and [[metabolic syndrome]]		*Associated with insulin resistance and [[metabolic syndrome]]

Rossdonaldson1 at 23:03, 13 November 2024

2024-11-13T23:03:54Z

← Older revision		Revision as of 23:03, 13 November 2024
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	[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]		[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
	[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]		[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]
			[[File:Liver vascular anatomy.png\|thumb\|Liver vascular anatomy.]]
	*Fatty liver disease due to causes other than excessive alcohol		*Fatty liver disease due to causes other than excessive alcohol
	*Associated with insulin resistance and [[metabolic syndrome]]		*Associated with insulin resistance and [[metabolic syndrome]]

Rossdonaldson1: /* Background */

2024-11-13T22:59:12Z

Background

← Older revision		Revision as of 22:59, 13 November 2024
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	==Background==		==Background==
	[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]		[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
			[[File:Sobo 1906 389.png\|thumb\|Inferior view of the liver with surface showing lobes and impressions.]]
	*Fatty liver disease due to causes other than excessive alcohol		*Fatty liver disease due to causes other than excessive alcohol
	*Associated with insulin resistance and [[metabolic syndrome]]		*Associated with insulin resistance and [[metabolic syndrome]]

Rossdonaldson1: /* Differential Diagnosis */

2022-09-07T20:48:33Z

Differential Diagnosis

← Older revision		Revision as of 20:48, 7 September 2022
Line 10:		Line 10:

	==Differential Diagnosis==		==Differential Diagnosis==
	*[[Cirrhosis]]
	*[[Hepatitis]]
	*[[Viral hepatitis]]
	*[[Autoimmune hepatitis]]
	*[[Wilson's disease]]
	*[[Hemochromatosis]]
	*[[Hepatocellular carcinoma]]
	*[[CHF]] (right heart failure

	{{Hepatomegaly DDX}}		{{Hepatomegaly DDX}}

Rossdonaldson1: /* Differential Diagnosis */

2022-09-07T20:47:40Z

Differential Diagnosis

← Older revision		Revision as of 20:47, 7 September 2022
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	*[[Hemochromatosis]]		*[[Hemochromatosis]]
	*[[Hepatocellular carcinoma]]		*[[Hepatocellular carcinoma]]
	*[[CHF]] (right heart failure]]		*[[CHF]] (right heart failure

			{{Hepatomegaly DDX}}

	==Evaluation==		==Evaluation==

Rossdonaldson1: /* Background */

2022-09-07T19:51:43Z

Background

← Older revision		Revision as of 19:51, 7 September 2022
Line 1:		Line 1:
	==Background==		==Background==
			[[File:Stage of liver damage high.jpg\|thumb\|Stages of non-alcoholic fatty liver disease, progressing from healthy, to steatosis (fat accumulation), inflammation, fibrosis and cirrhosis.]]
	*Fatty liver disease due to causes other than excessive alcohol		*Fatty liver disease due to causes other than excessive alcohol
	*Associated with insulin resistance and [[metabolic syndrome]]		*Associated with insulin resistance and [[metabolic syndrome]]