Monkeypox - Revision history

Rossdonaldson1 at 16:54, 7 September 2022

2022-09-07T16:54:20Z

← Older revision		Revision as of 16:54, 7 September 2022
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	*Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding		*Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding

	==Clinical Features~~<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>~~==		==Clinical Features==
	[[File:2BE0JCC..jpg\|thumb\|Monkeypox]]		[[File:2BE0JCC..jpg\|thumb\|Monkeypox]]
	[[File:MonkeyPox-key-characteristics.png\|thumb]]		[[File:MonkeyPox-key-characteristics.png\|thumb]]
	*Results in a smallpox-like disease in humans.		*Results in a smallpox-like disease in humans.
	*The incubation period (interval from infection to onset of symptoms) of monkeypox can range from 5 to 21 days.		*The incubation period (interval from infection to onset of symptoms) of monkeypox can range from 5 to 21 days.<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>
	*Typically presents clinically with fever, rash and swollen lymph nodes.		*Typically presents clinically with fever, rash and swollen lymph nodes.<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>
	*Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy.		*Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy. <ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>
	**Lymphadenopathy is a distinctive feature of monkeypox compared to other diseases that may initially appear similar (e.g. [[chickenpox]], [[measles]], [[smallpox]]).		**Lymphadenopathy is a distinctive feature of monkeypox compared to other diseases that may initially appear similar (e.g. [[chickenpox]], [[measles]], [[smallpox]]).
	*Skin eruption usually begins within 1-3 days of appearance of fever.		*Skin eruption usually begins within 1-3 days of appearance of fever.

Rossdonaldson1: /* BackgroundBunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141 */

2022-09-07T16:49:32Z

BackgroundBunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141

← Older revision		Revision as of 16:49, 7 September 2022
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	==Background<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>==		==Background==
	*A zoonotic disease		*A zoonotic disease
	*Caused by an orthopoxvirus,		*Caused by an orthopoxvirus
	*Initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years.		*Initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years. <ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>
	*Overall case fatality rate of 8.7%		*Overall case fatality rate of 8.7%<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>
	*Interactions with infected animals or individuals are risk behaviors associated with acquiring monkeypox.		*Interactions with infected animals or individuals are risk behaviors associated with acquiring monkeypox.

Rossdonaldson1 at 16:48, 7 September 2022

2022-09-07T16:48:10Z

← Older revision		Revision as of 16:48, 7 September 2022
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	==Background==		==Background<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>==
	*A zoonotic disease<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>		*A zoonotic disease
	*Caused by an orthopoxvirus~~<ref>Bunge EM~~, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>		*Caused by an orthopoxvirus,
	*Initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years.		*Initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years.
	*Overall case fatality rate of 8.7%		*Overall case fatality rate of 8.7%
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	===Transmission===		===Transmission===
	*Mostly transmitted to people from wild animals such as rodents and primates		*Mostly transmitted to people from wild animals such as rodents and primates, but human-to-human transmission also occurs
	**Bite or scratch,		*Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding
	**Direct contact with body fluids or lesions from an infected animal or contaminated material (indirect contact)
	**Eating inadequately cooked meat of an infected animal
	*Human-to-human transmission
	**Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding
	**Transmission via droplet respiratory particles usually requires prolonged face-to-face contact, which puts health workers, household members and other close contacts of active cases at greater risk.<ref>Shahid, S. (n.d.). The American College of Emergency Physicians Guide to Monkeypox Disease. The American College of Emergency Physicians. Retrieved August 13, 2022, from https://www.acep.org/monkeypox-field-guide/cover-page/ </ref>

	==Clinical Features==		==Clinical Features<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>==
	[[File:2BE0JCC..jpg\|thumb\|Monkeypox]]		[[File:2BE0JCC..jpg\|thumb\|Monkeypox]]
	[[File:MonkeyPox-key-characteristics.png\|thumb]]		[[File:MonkeyPox-key-characteristics.png\|thumb]]
	*Results in a smallpox-like disease in humans.		*Results in a smallpox-like disease in humans.
	*The incubation period (interval from infection to onset of symptoms) of monkeypox can range from 5 to 21 days.~~<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>~~		*The incubation period (interval from infection to onset of symptoms) of monkeypox can range from 5 to 21 days.
	*Typically presents clinically with fever, rash and swollen lymph nodes.		*Typically presents clinically with fever, rash and swollen lymph nodes.
	*Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy.		*Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy.
	**Lymphadenopathy is a distinctive feature of monkeypox compared to other diseases that may initially appear similar (e.g. [[chickenpox]], [[measles]], [[smallpox]]).		**Lymphadenopathy is a distinctive feature of monkeypox compared to other diseases that may initially appear similar (e.g. [[chickenpox]], [[measles]], [[smallpox]]).
	*Skin eruption usually begins within 1-3 days of appearance of fever. ~~<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>~~		*Skin eruption usually begins within 1-3 days of appearance of fever.
	**The rash tends to be more concentrated on the face and extremities rather than on the trunk.		**The rash tends to be more concentrated on the face and extremities rather than on the trunk.
	**It affects the face (in 95% of cases), and palms of the hands and soles of the feet (in 75% of cases).		**It affects the face (in 95% of cases), and palms of the hands and soles of the feet (in 75% of cases).
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	==Differential Diagnosis==		==Differential Diagnosis==
			*Measles
			*Multiple Endocrine Neoplasia (MEN)

	{{Bullous rashes DDX}}		{{Bullous rashes DDX}}

Rossdonaldson1: /* Differential Diagnosis */

2022-08-17T20:10:05Z

Differential Diagnosis

← Older revision		Revision as of 20:10, 17 August 2022
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	==Differential Diagnosis==		==Differential Diagnosis==
	*[[Measles]]
	*Multiple Endocrine Neoplasia (MEN)

	{{Bullous rashes DDX}}		{{Bullous rashes DDX}}

Rossdonaldson1: /* Clinical FeaturesWorld Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox */

2022-08-17T18:57:48Z

Clinical FeaturesWorld Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox

← Older revision		Revision as of 18:57, 17 August 2022
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	**Transmission via droplet respiratory particles usually requires prolonged face-to-face contact, which puts health workers, household members and other close contacts of active cases at greater risk.<ref>Shahid, S. (n.d.). The American College of Emergency Physicians Guide to Monkeypox Disease. The American College of Emergency Physicians. Retrieved August 13, 2022, from https://www.acep.org/monkeypox-field-guide/cover-page/ </ref>		**Transmission via droplet respiratory particles usually requires prolonged face-to-face contact, which puts health workers, household members and other close contacts of active cases at greater risk.<ref>Shahid, S. (n.d.). The American College of Emergency Physicians Guide to Monkeypox Disease. The American College of Emergency Physicians. Retrieved August 13, 2022, from https://www.acep.org/monkeypox-field-guide/cover-page/ </ref>

	==Clinical Features~~<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>~~==		==Clinical Features==
	[[File:2BE0JCC..jpg\|thumb\|Monkeypox]]		[[File:2BE0JCC..jpg\|thumb\|Monkeypox]]
	[[File:MonkeyPox-key-characteristics.png\|thumb]]		[[File:MonkeyPox-key-characteristics.png\|thumb]]
	*Results in a smallpox-like disease in humans.		*Results in a smallpox-like disease in humans.
	*The incubation period (interval from infection to onset of symptoms) of monkeypox can range from 5 to 21 days.		*The incubation period (interval from infection to onset of symptoms) of monkeypox can range from 5 to 21 days.<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>
	*Typically presents clinically with fever, rash and swollen lymph nodes.		*Typically presents clinically with fever, rash and swollen lymph nodes.
	*Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy.		*Characterized by fever, intense headache, lymphadenopathy myalgia and lethargy.
	**Lymphadenopathy is a distinctive feature of monkeypox compared to other diseases that may initially appear similar (e.g. [[chickenpox]], [[measles]], [[smallpox]]).		**Lymphadenopathy is a distinctive feature of monkeypox compared to other diseases that may initially appear similar (e.g. [[chickenpox]], [[measles]], [[smallpox]]).
	*Skin eruption usually begins within 1-3 days of appearance of fever.		*Skin eruption usually begins within 1-3 days of appearance of fever. <ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>
	**The rash tends to be more concentrated on the face and extremities rather than on the trunk.		**The rash tends to be more concentrated on the face and extremities rather than on the trunk.
	**It affects the face (in 95% of cases), and palms of the hands and soles of the feet (in 75% of cases).		**It affects the face (in 95% of cases), and palms of the hands and soles of the feet (in 75% of cases).

Rossdonaldson1: /* Transmission */

2022-08-17T18:57:02Z

Transmission

← Older revision		Revision as of 18:57, 17 August 2022
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	*Interactions with infected animals or individuals are risk behaviors associated with acquiring monkeypox.		*Interactions with infected animals or individuals are risk behaviors associated with acquiring monkeypox.

	==Transmission==		===Transmission===
	*Mostly transmitted to people from wild animals such as rodents and primates		*Mostly transmitted to people from wild animals such as rodents and primates
	**Bite or scratch,		**Bite or scratch,

Rossdonaldson1 at 18:52, 17 August 2022

2022-08-17T18:52:30Z

← Older revision		Revision as of 18:52, 17 August 2022
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	==Background<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>==		==Background==
	*A zoonotic disease		*A zoonotic disease<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>
	*Caused by an orthopoxvirus,		*Caused by an orthopoxvirus<ref>Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. (2022) The changing epidemiology of human monkeypox—A potential threat? A systematic review. PLoS Negl Trop Dis 16(2): e0010141. https://doi.org/10.1371/journal.pntd.0010141</ref>
	*Initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years.		*Initially diagnosed in 1970 in the Democratic Republic of the Congo (DRC), it has spread to other regions of Africa (primarily West and Central), and cases outside Africa have emerged in recent years.
	*Overall case fatality rate of 8.7%		*Overall case fatality rate of 8.7%
	*Interactions with infected animals or individuals are risk behaviors associated with acquiring monkeypox.		*Interactions with infected animals or individuals are risk behaviors associated with acquiring monkeypox.



	==Transmission==		==Transmission==
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	==Differential Diagnosis==		==Differential Diagnosis==
	*Measles		*[[Measles]]
	*Multiple Endocrine Neoplasia (MEN)		*Multiple Endocrine Neoplasia (MEN)

Jonrako: /* Transmission */

2022-08-14T21:10:31Z

Transmission

← Older revision		Revision as of 21:10, 14 August 2022
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	*Human-to-human transmission		*Human-to-human transmission
	**Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding		**Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding
	*Transmission via droplet respiratory particles usually requires prolonged face-to-face contact, which puts health workers, household members and other close contacts of active cases at greater risk.<ref>Shahid, S. (n.d.). The American College of Emergency Physicians Guide to Monkeypox Disease. The American College of Emergency Physicians. Retrieved August 13, 2022, from https://www.acep.org/monkeypox-field-guide/cover-page/ </ref>		**Transmission via droplet respiratory particles usually requires prolonged face-to-face contact, which puts health workers, household members and other close contacts of active cases at greater risk.<ref>Shahid, S. (n.d.). The American College of Emergency Physicians Guide to Monkeypox Disease. The American College of Emergency Physicians. Retrieved August 13, 2022, from https://www.acep.org/monkeypox-field-guide/cover-page/ </ref>

	==Clinical Features<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>==		==Clinical Features<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>==

Jonrako: /* Transmission */

2022-08-14T21:09:54Z

Transmission

← Older revision		Revision as of 21:09, 14 August 2022
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	==Transmission==		==Transmission==
	*Mostly transmitted to people from wild animals such as rodents and primates, ~~but human~~-to-human transmission ~~also occurs~~		*Mostly transmitted to people from wild animals such as rodents and primates
	*Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding		**Bite or scratch,
			**Direct contact with body fluids or lesions from an infected animal or contaminated material (indirect contact)
			**Eating inadequately cooked meat of an infected animal
			*Human-to-human transmission
			**Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding
			*Transmission via droplet respiratory particles usually requires prolonged face-to-face contact, which puts health workers, household members and other close contacts of active cases at greater risk.<ref>Shahid, S. (n.d.). The American College of Emergency Physicians Guide to Monkeypox Disease. The American College of Emergency Physicians. Retrieved August 13, 2022, from https://www.acep.org/monkeypox-field-guide/cover-page/ </ref>

	==Clinical Features<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>==		==Clinical Features<ref>World Health Organization. (n.d.). Monkeypox. World Health Organization. Retrieved May 19, 2022, from https://www.who.int/news-room/fact-sheets/detail/monkeypox </ref>==

Jonrako: /* Evaluation of Transmission Risk */

2022-08-13T17:43:08Z

Evaluation of Transmission Risk

← Older revision		Revision as of 17:43, 13 August 2022
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	==~~Evaluation of~~ Transmission ~~Risk~~==		==Transmission==
	*Mostly transmitted to people from wild animals such as rodents and primates, but human-to-human transmission also occurs		*Mostly transmitted to people from wild animals such as rodents and primates, but human-to-human transmission also occurs
	*Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding		*Transmitted from one person to another by contact with lesions, body fluids, respiratory droplets and contaminated materials such as bedding