Neisseria gonorrhoeae - Revision history

Danbot: Add Cefuroxime AntibioticDose entry from original Cefuroxime page

2026-03-20T12:36:52Z

Add Cefuroxime AntibioticDose entry from original Cefuroxime page

← Older revision		Revision as of 12:36, 20 March 2026
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	====Pediatric====		====Pediatric====
	*{{AntibioticDose\|drug=Doxycycline\|dose=>8 years old/>45 kg; 100mg PO q12h x 7 days; Not first line- use with [[ceftriaxone]]\|context=Gonorrhea\|disease=Neisseria gonorrhoeae\|population=Pediatric}}		*{{AntibioticDose\|drug=Doxycycline\|dose=>8 years old/>45 kg; 100mg PO q12h x 7 days; Not first line- use with [[ceftriaxone]]\|context=Gonorrhea\|disease=Neisseria gonorrhoeae\|population=Pediatric}}
			*{{AntibioticDose\|drug=Cefuroxime\|dose=1000mg PO x 1\|context=Uncomplicated urethral/cervical/rectal infection, alternative regimen\|disease=Neisseria gonorrhoeae\|population=Adult}}

	==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2010</ref>==		==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2010</ref>==

Danbot: Add Doxycycline and Gentamicin AntibioticDose entries

2026-03-20T10:59:18Z

Add Doxycycline and Gentamicin AntibioticDose entries

← Older revision		Revision as of 10:59, 20 March 2026
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	*[[Septic arthritis]]		*[[Septic arthritis]]
	*[[Urethritis]]		*[[Urethritis]]


			===Antibiotic Dosing===
			====Adult====
			*{{AntibioticDose\|drug=Gentamicin\|dose=240mg IM x 1\|context=Uncomplicated Gonococcal\|disease=Neisseria gonorrhoeae\|population=Adult}}
			====Pediatric====
			*{{AntibioticDose\|drug=Doxycycline\|dose=>8 years old/>45 kg; 100mg PO q12h x 7 days; Not first line- use with [[ceftriaxone]]\|context=Gonorrhea\|disease=Neisseria gonorrhoeae\|population=Pediatric}}

	==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2010</ref>==		==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2010</ref>==

Rossdonaldson1 at 18:40, 23 December 2020

2020-12-23T18:40:51Z

← Older revision		Revision as of 18:40, 23 December 2020
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	==Background==		==Background==
	*Commonly known as gonorrhea		*Commonly known as gonorrhea or "GC"
	*Fastidious [[gram-negative cocci]]		*Fastidious [[gram-negative cocci]]

Rossdonaldson1: /* Management */

2020-12-23T18:40:20Z

Management

@@ Line 20: / Line 20: @@
 ==Management==
 {{Presumed GC chlamydia of cervix, urethra, or rectum}}
+{{Presumed GC chlamydia of pharynx}}
 ===Specific Disease Processes===

Rossdonaldson1: /* Management */

2020-12-23T18:39:31Z

Management

@@ Line 19: / Line 19: @@
 ==Management==
-===Presumed [[GC]]/[[chlamydia]] of cervix, urethra, or rectum (uncomplicated)<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>===
+{{Presumed GC chlamydia of cervix, urethra, or rectum}}
 ===Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>===

Rossdonaldson1: /* Management */

2020-12-23T18:38:51Z

Management

← Older revision		Revision as of 18:38, 23 December 2020
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	==Management==		==Management==
	~~===General Antibiotic Guidelines===~~		===Presumed [[GC]]/[[chlamydia]] of cervix, urethra, or rectum (uncomplicated)<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>===
	====Presumed [[GC]]/[[chlamydia]] of cervix, urethra, or rectum (uncomplicated)<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====
	''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>		''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>
	<br>		<br>
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	^Additional chlamydia coverage only needed if treated with cefixime only		^Additional chlamydia coverage only needed if treated with cefixime only

	====Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====		===Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>===
	<u>Standard</u><br>		<u>Standard</u><br>
	''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>		''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>

Rossdonaldson1: /* Specific Disease Processes */

2020-12-23T18:35:26Z

Specific Disease Processes

← Older revision		Revision as of 18:35, 23 December 2020
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	===Specific Disease Processes===		===Specific Disease Processes===
			*[[Cervicitis]]
	*[[Gonorrheal conjunctivitis\|Conjunctivitis]]		*[[Gonorrheal conjunctivitis\|Conjunctivitis]]
	*[[Epididymitis]]		*[[Epididymitis]]

Rossdonaldson1: /* Presumed GC/chlamydia of the pharynx (uncomplicated):Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916 */

2020-12-23T18:33:49Z

Presumed GC/chlamydia of the pharynx (uncomplicated):Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916

← Older revision		Revision as of 18:33, 23 December 2020
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	<br>		<br>
	<u>Ceftriaxone contraindicated</u><br>		<u>Ceftriaxone contraindicated</u><br>
	*No reliable alternative treatments are available for pharyngeal gonorrhea. For persons with a history of a beta-lactam allergy, a thorough assessment of the reaction is recommended.<ref>CDC. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep 2015;64(No. RR-3). https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6403a1.htm.</ref>		*No reliable alternative treatments are available for pharyngeal gonorrhea
	*For persons with an anaphylactic or other severe reaction (e.g. [[Stevens Johnson syndrome]]) to ceftriaxone, consult an infectious disease specialist for an alternative treatment recommendation.		**For persons with a history of a beta-lactam allergy, a thorough assessment of the reaction is recommended.<ref>CDC. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep 2015;64(No. RR-3). https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6403a1.htm.</ref>
			**For persons with an anaphylactic or other severe reaction (e.g. [[Stevens Johnson syndrome]]) to ceftriaxone, consult an infectious disease specialist for an alternative treatment recommendation.

	===Specific Disease Processes===		===Specific Disease Processes===

Rossdonaldson1: /* Presumed GC/chlamydia of the pharynx (uncomplicated):Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916 */

2020-12-23T18:32:37Z

← Older revision		Revision as of 18:32, 23 December 2020
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	====Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====		====Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====
	<u>Standard</u><br>		<u>Standard</u><br>
			''Typically, treatment for '''both''' gonorrhea and chlamydia is indicated, if one entity is suspected.''<br>
			<br>
	*Gonorrhea		*Gonorrhea
	**[[Ceftriaxone]] IM x 1		**[[Ceftriaxone]] IM x 1
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	**Pregnant: [[azithromycin]] 1 g PO x 1		**Pregnant: [[azithromycin]] 1 g PO x 1

			<br>
	<u>Ceftriaxone contraindicated</u><br>		<u>Ceftriaxone contraindicated</u><br>
	*No reliable alternative treatments are available for pharyngeal gonorrhea. For persons with a history of a beta-lactam allergy, a thorough assessment of the reaction is recommended.<ref>CDC. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep 2015;64(No. RR-3). https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6403a1.htm.</ref>		*No reliable alternative treatments are available for pharyngeal gonorrhea. For persons with a history of a beta-lactam allergy, a thorough assessment of the reaction is recommended.<ref>CDC. Sexually transmitted diseases treatment guidelines. MMWR Recomm Rep 2015;64(No. RR-3). https://www.cdc.gov/mmwr/preview/mmwrhtml/rr6403a1.htm.</ref>

Rossdonaldson1: /* [Presumed GC/chlamydia of the pharynx (uncomplicated):Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916 */

2020-12-23T18:32:04Z

[Presumed GC/chlamydia of the pharynx (uncomplicated):Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916

← Older revision		Revision as of 18:32, 23 December 2020
Line 43:		Line 43:
	^Additional chlamydia coverage only needed if treated with cefixime only		^Additional chlamydia coverage only needed if treated with cefixime only

	====[Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====		====Presumed [[GC]]/[[chlamydia]] of the pharynx (uncomplicated):<ref>Cyr SS et al. Update to CDC’s Treatment Guidelines for Gonococcal Infection, 2020. MMWR. Center for Disease Control and Prevention. 2020. 69(50):1911-1916</ref>====
	<u>Standard</u><br>		<u>Standard</u><br>
	*Gonorrhea		*Gonorrhea