Norepinephrine - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:56:30Z

Switch SMW query from broadtable to table format for better layout with TOC

← Older revision		Revision as of 21:56, 20 March 2026
Line 75:		Line 75:
	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T17:23:54Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

← Older revision		Revision as of 17:23, 20 March 2026
Line 77:		Line 77:
	\|format=broadtable		\|format=broadtable
	\|headers=plain		\|headers=plain
	\|~~link~~=~~subject~~		\|mainlabel=-
	\|sort=Has Indication		\|sort=Has Indication
	\|limit=50		\|limit=50

Danbot: Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

2026-03-20T16:42:03Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

@@ Line 64: / Line 64: @@
 **If marked hypotension (SBP <70)
 **If used with [[dobutamine]]
 ==See Also==

Ostermayer at 16:01, 25 July 2025

2025-07-25T16:01:45Z

← Older revision		Revision as of 16:01, 25 July 2025
Line 1:		Line 1:
	==General==		==General==
	*Type: [[Vasopressors]]		*Type: [[Is DrugClass::Vasopressors]]
	*Dosage Forms: IV		*Dosage Forms: IV
	*Common Trade Names: Levophed		*Common Trade Names: Levophed

Elcatracho: /* General */

2023-12-28T23:30:05Z

General

← Older revision		Revision as of 23:30, 28 December 2023
Line 1:		Line 1:
	==General==		==General==
	*Type: [[Vasopressors]]		*Type: [[Vasopressors]]
	*Dosage Forms:		*Dosage Forms: IV
	*Common Trade Names: Levophed		*Common Trade Names: Levophed

Elcatracho: /* Adverse Reactions */

2022-01-04T10:35:59Z

Adverse Reactions

← Older revision		Revision as of 10:35, 4 January 2022
Line 37:		Line 37:

	==Adverse Reactions==		==Adverse Reactions==
	*If extravasation occurs use phentolamine 0.1 to 0.2mg/kg (maximum dose 10mg) subcutaneous in affected site<ref>ZUCKER G. et al. Treatment of shock and prevention of ischemic necrosis with levarterenol-phentolamine mixtures. Circulation. 1960 Nov;22:935-7.</ref><ref>PELNER L. et al. The problem of levarterenol (norepinephrine) extravasation an experimental study.. Am J Med Sci. 1958 Dec;236(6):755-66</ref>		*If extravasation occurs use [[phentolamine]] 0.1 to 0.2mg/kg (maximum dose 10mg) subcutaneous in affected site<ref>ZUCKER G. et al. Treatment of shock and prevention of ischemic necrosis with levarterenol-phentolamine mixtures. Circulation. 1960 Nov;22:935-7.</ref><ref>PELNER L. et al. The problem of levarterenol (norepinephrine) extravasation an experimental study.. Am J Med Sci. 1958 Dec;236(6):755-66</ref>
	**Consult plastic/general surgery service to follow the patient and eval for need for intervention		**Consult plastic/general surgery service to follow the patient and eval for need for intervention

Elcatracho: /* Indication */

2022-01-04T10:35:21Z

Indication

← Older revision		Revision as of 10:35, 4 January 2022
Line 63:		Line 63:
	*Cardiogenic shock:		*Cardiogenic shock:
	**If marked hypotension (SBP <70)		**If marked hypotension (SBP <70)
	**If used with dobutamine		**If used with [[dobutamine]]

	==See Also==		==See Also==

ClaireLewis at 00:02, 23 September 2019

2019-09-23T00:02:41Z

← Older revision		Revision as of 00:02, 23 September 2019
Line 24:		Line 24:

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: C
	*Lactation: Unknown if excreted in breast milk		*Lactation: Unknown if excreted in breast milk
	*Renal Dosing		*Renal Dosing
Line 74:		Line 74:
	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:Critical Care]]

Bmurray990: /* Special Populations */

2019-01-24T16:13:46Z

Special Populations

← Older revision		Revision as of 16:13, 24 January 2019
Line 20:		Line 20:

	==Pediatric Dosing==		==Pediatric Dosing==
			*Hypotension/Shock
			**IV Infusion: Initiate at 0.05-0.1mcg/kg/min, titrate to effect, usual max dose 2mcg/kg/min

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:
	*Lactation:		*Lactation: Unknown if excreted in breast milk
	*Renal Dosing		*Renal Dosing
	**Adult		**Adult
Line 38:		Line 40:
	**Consult plastic/general surgery service to follow the patient and eval for need for intervention		**Consult plastic/general surgery service to follow the patient and eval for need for intervention

	~~===Serious===~~		*Cardiovascular: Bradycardia, Arrhythmia, Cardiomyopathy
			*CNS Anxiety, Headache
	~~===Common===~~		*Respiratory: Dyspnea

	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: Effects for 1-2min
	*Metabolism:		*Metabolism: In the blood via COMT and MAO
	*Excretion:		*Excretion: Renal
	*Mechanism of Action:		*Mechanism of Action:
	===Primary Receptor===		===Primary Receptor===

Neil.m.young: Text replacement - "α1" to "α₁"

2017-08-04T17:29:11Z

Text replacement - "α1" to "α<sub>1</sub>"

← Older revision		Revision as of 17:29, 4 August 2017
Line 48:		Line 48:
	*Mechanism of Action:		*Mechanism of Action:
	===Primary Receptor===		===Primary Receptor===
	*α1 >> β<sub>1</sub>		*α<sub>1</sub> >> β<sub>1</sub>
	===Relative Effects===		===Relative Effects===
	*↑↑↑SVR		*↑↑↑SVR