Omeprazole - Revision history

Elcatracho: /* See Also */

2021-03-05T19:40:05Z

ClaireLewis at 00:44, 23 September 2019

2019-09-23T00:44:15Z

← Older revision		Revision as of 00:44, 23 September 2019
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	==Adult Dosing==		==Adult Dosing==
	===[[GERD]]===		===[[GERD]]===
	*PO once daily, taken about 1 hour before meals		*20mg PO once daily, taken about 1 hour before meals

	===[[Peptic ulcers]]===		===[[Peptic ulcers]]===
			*40mg PO daily
	~~===[[Esophagitis]]===~~

	===Zollinger Ellison syndrome===		===Zollinger Ellison syndrome===
			*60mg PO q8-24h

	==Pediatric Dosing==		==Pediatric Dosing==
			===GERD===
			*<1 year: Safety and efficacy not established
			*5-10 kg: 5 mg PO qDay
			*10-20 kg: 10 mg PO qDay
			*>20 kg: 20 mg PO qDay
			===Erosive Esophagitis===
			*<1 month: Safety and efficacy not established
			*Aged 1 month to <1 year
			**3 to <5 kg: 2.5 mg qDay
			**5 to <10 kg: 5 mg qDay
			**≥10 kg: 10 mg qDay
			*Aged 1-16 years
			**5 to <10 kg: 5 mg PO qDay
			**10 to <20 kg: 10 mg PO qDay
			**≥20 kg: 20 mg PO qDay

	==Special Populations==		==Special Populations==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: C
	*[[Lactation risk categories\|Lactation risk]]:		*[[Lactation risk categories\|Lactation risk]]: May be present in milk
	===Renal Dosing===		===Renal Dosing===
	*~~Adult:~~		*No adjustment
	*Pediatric:
	===Hepatic Dosing===		===Hepatic Dosing===
	*~~Adult:~~		*Not studied
	*Pediatric:

	==Contraindications==		==Contraindications==
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
			*Agranulocytosis
			*Fractures, osteoporosis-related
			*Hepatotoxicity
			*Pancreatitis
			*Interstitial nephritis
			*Rhabdomyolysis

	===Common===		===Common===
			*Headache, dizziness
			*Nausea/vomiting, diarrhea, abdominal pain, flatulence, acid regurgitation, constipation
			*URI, cough
			*Rash
			*Gastric polyps
			*Alopecia
			*Atrophic gastritis

	==Pharmacology==		==Pharmacology==
	*Half-life: 1-1.2 hours <ref>Prilosec Prescribing Information. AstraZeneca Pharmaceuticals.</ref>		*Half-life: 1-1.2 hours <ref>Prilosec Prescribing Information. AstraZeneca Pharmaceuticals.</ref>
	*Metabolism: Hepatic (CYP2C19, CYP3A4) <ref>Prilosec Prescribing Information. AstraZeneca Pharmaceuticals.</ref>		*Metabolism: Hepatic (CYP2C19, CYP3A4) <ref>Prilosec Prescribing Information. AstraZeneca Pharmaceuticals.</ref>
	*Excretion:		*Excretion: Urine

	==Mechanism of Action==		==Mechanism of Action==
			*PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in suppression of basal and stimulated acid secretion

	==Comments==		==Comments==
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	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:GI]]

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-21T11:12:17Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 11:12, 21 July 2016
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	==Administration==		==Administration==
	*Type: [[Proton pump inhibitor]] (PPI)		*Type: [[Proton pump inhibitor]] (PPI)
	*Dosage Forms: Tablets or capsules of 10, 20, 40, ~~80 mg~~. Powder of omeprazole sodium for IV.		*Dosage Forms: Tablets or capsules of 10, 20, 40, 80mg. Powder of omeprazole sodium for IV.
	*Routes of Administration: PO, IV		*Routes of Administration: PO, IV
	*Common Trade Names: Prilosec		*Common Trade Names: Prilosec

Ostermayer: Text replacement - "Category:Drugs" to "Category:Pharmacology"

2016-03-22T15:54:27Z

Text replacement - "Category:Drugs" to "Category:Pharmacology"

← Older revision		Revision as of 15:54, 22 March 2016
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	==References==		==References==
	<references/>		<references/>
	[[Category:~~Drugs~~]]		[[Category:Pharmacology]]

Rossdonaldson1: /* Administration */

2015-10-27T21:12:11Z

Administration

← Older revision		Revision as of 21:12, 27 October 2015
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	==Administration==		==Administration==
	*Type: Proton pump inhibitor (PPI)		*Type: [[Proton pump inhibitor]] (PPI)
	*Dosage Forms: Tablets or capsules of 10, 20, 40, 80 mg. Powder of omeprazole sodium for IV.		*Dosage Forms: Tablets or capsules of 10, 20, 40, 80 mg. Powder of omeprazole sodium for IV.
	*Routes of Administration: PO, IV		*Routes of Administration: PO, IV

Catierey: formatting

2015-09-22T16:05:02Z

formatting

← Older revision		Revision as of 16:05, 22 September 2015
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	*PO once daily, taken about 1 hour before meals		*PO once daily, taken about 1 hour before meals

	===[[[Peptic ulcers]]===		===[[Peptic ulcers]]===

	===[[Esophagitis]]===		===[[Esophagitis]]===

Catierey: created page

2015-09-22T16:04:46Z

created page

New page

==Administration==
*Type: Proton pump inhibitor (PPI)
*Dosage Forms: Tablets or capsules of 10, 20, 40, 80 mg. Powder of omeprazole sodium for IV.
*Routes of Administration: PO, IV
*Common Trade Names: Prilosec

==Adult Dosing==
===[[GERD]]===
*PO once daily, taken about 1 hour before meals

===[[[Peptic ulcers]]===

===[[Esophagitis]]===

===Zollinger Ellison syndrome===

==Pediatric Dosing==

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
*[[Lactation risk categories|Lactation risk]]:
===Renal Dosing===
*Adult:
*Pediatric:
===Hepatic Dosing===
*Adult:
*Pediatric:

==Contraindications==
*Allergy to class/drug

==Adverse Reactions==
===Serious===

===Common===

==Pharmacology==
*Half-life: 1-1.2 hours <ref>Prilosec Prescribing Information. AstraZeneca Pharmaceuticals.</ref>
*Metabolism: Hepatic (CYP2C19, CYP3A4) <ref>Prilosec Prescribing Information. AstraZeneca Pharmaceuticals.</ref>
*Excretion:

==Mechanism of Action==

==Comments==

==See Also==

==References==
<references/>
[[Category:Drugs]]

← Older revision		Revision as of 19:40, 5 March 2021
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	==See Also==		==See Also==
			*[[Proton-pump inhibitor]]

	==References==		==References==