Osteosarcoma - Revision history

Rossdonaldson1: /* References */

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References

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categorize page

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Differential Diagnosis

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 ==Differential Diagnosis==
-===Malignant===
+{{Bone tumors and their mimics DDX}}
 ==Evaluation==

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BackgroundNiederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.

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	**3% of all childhood cancers		**3% of all childhood cancers
	*Around two-thirds of those diagnosed with non-metastatic disease under the age of 40 will be long-term survivors or cured of the disease with appropriate treatment		*Around two-thirds of those diagnosed with non-metastatic disease under the age of 40 will be long-term survivors or cured of the disease with appropriate treatment
	*Survival is less than 20 ~~percent~~ with metastatic disease		*Survival is less than 20% with metastatic disease
	**One-fifth will have metastases at presentation		**One-fifth will have metastases at presentation
	**Most common metastatic site is lung followed by bone		**Most common metastatic site is lung followed by bone

2019-12-11T02:42:58Z

BackgroundNiederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.

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	==Background<ref>Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.</ref>==		==Background<ref>Niederhuber, John E., et al. “Sarcomas.” Abeloff's Clinical Oncology E-Book. Elsevier Health Sciences, 2019, pp. 1604 – 1654.e8.</ref>==
			[[File:Predilection sites of osteosarcoma2.png\|thumb\|Osteosarcoma occurrence sites]]
	*Most common primary pediatric bone tumor		*Most common primary pediatric bone tumor
	**3% of all childhood cancers		**3% of all childhood cancers

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Benign

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Malignant

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Evaluation

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	**"Sunburst" pattern on X-ray		**"Sunburst" pattern on X-ray
	***This pattern describes a lytic lesion with periosteal reaction and cortical disruption at or near the metaphysis		***This pattern describes a lytic lesion with periosteal reaction and cortical disruption at or near the metaphysis
	[[File:Figure1A_Osteosarcoma.jpg\|thumb\|(A) Sunburst appearance of Osteosarcoma.]][[File:Figure1B_Osteosarcoma.jpg\|thumb\|(B) Ultrasound of same patient showing cortical destruction and boney mass.]]		[[File:Figure1A_Osteosarcoma.jpg\|thumb\|(A) Sunburst appearance of Osteosarcoma.]][[File:Figure1B_Osteosarcoma.jpg\|thumb\|(B) Ultrasound of same patient in (A) showing cortical destruction and boney mass.]]
	**Codman triangle		**Codman triangle
	***New subperiosteal bone formed when the periosteum is raised away from the bone		***New subperiosteal bone formed when the periosteum is raised away from the bone

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Evaluation

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	**"Sunburst" pattern on X-ray		**"Sunburst" pattern on X-ray
	***This pattern describes a lytic lesion with periosteal reaction and cortical disruption at or near the metaphysis		***This pattern describes a lytic lesion with periosteal reaction and cortical disruption at or near the metaphysis
	~~***~~[[File:Figure1A_Osteosarcoma.jpg\|thumb\|(A) Sunburst appearance of Osteosarcoma.]][[File:Figure1B_Osteosarcoma.jpg\|thumb\|(B) Ultrasound of same patient showing cortical destruction and boney mass.]]		[[File:Figure1A_Osteosarcoma.jpg\|thumb\|(A) Sunburst appearance of Osteosarcoma.]][[File:Figure1B_Osteosarcoma.jpg\|thumb\|(B) Ultrasound of same patient showing cortical destruction and boney mass.]]

	**Codman triangle		**Codman triangle
	***New subperiosteal bone formed when the periosteum is raised away from the bone		***New subperiosteal bone formed when the periosteum is raised away from the bone

2019-11-21T22:05:31Z

Evaluation

← Older revision		Revision as of 22:05, 21 November 2019
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	***This pattern describes a lytic lesion with periosteal reaction and cortical disruption at or near the metaphysis		***This pattern describes a lytic lesion with periosteal reaction and cortical disruption at or near the metaphysis
	***[[File:Figure1A_Osteosarcoma.jpg\|thumb\|(A) Sunburst appearance of Osteosarcoma.]][[File:Figure1B_Osteosarcoma.jpg\|thumb\|(B) Ultrasound of same patient showing cortical destruction and boney mass.]]		***[[File:Figure1A_Osteosarcoma.jpg\|thumb\|(A) Sunburst appearance of Osteosarcoma.]][[File:Figure1B_Osteosarcoma.jpg\|thumb\|(B) Ultrasound of same patient showing cortical destruction and boney mass.]]

	**Codman triangle		**Codman triangle
	***New subperiosteal bone formed when the periosteum is raised away from the bone		***New subperiosteal bone formed when the periosteum is raised away from the bone