Pantoprazole - Revision history

Elcatracho: /* Serious */

2021-02-21T00:55:40Z

Serious

2021-02-21T00:54:57Z

Upper gastrointestinal bleeding

← Older revision		Revision as of 00:54, 21 February 2021
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	===[[Upper gastrointestinal bleeding]]===		===[[Upper gastrointestinal bleeding]]===
	*80mg IV x 1; then 8mg/hr OR 80mg IV BID		*80mg IV x 1; then 8mg/hr OR 80mg IV BID
			*Intermittent dosing is comparable to bolus then continuous drip<ref>Sachar H, Vaidya K, Laine L. Intermittent vs continuous proton pump inhibitor therapy for high-risk bleeding ulcers: a systematic review and meta-analysis. JAMA Intern Med. 2014;174(11):1755-1762. doi:10.1001/jamainternmed.2014.4056</ref>

	===[[GERD]], [[Peptic ulcer disease]], [[Esophagitis]]===		===[[GERD]], [[Peptic ulcer disease]], [[Esophagitis]]===
	*40mg IV or PO daily		*40mg IV or PO daily

2019-09-23T21:19:36Z

← Older revision		Revision as of 21:19, 23 September 2019
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	==Adult Dosing==		==Adult Dosing==
	===[[Upper gastrointestinal bleeding]]===		===[[Upper gastrointestinal bleeding]]===
	*80mg x 1; then 8mg/hr		*80mg IV x 1; then 8mg/hr OR 80mg IV BID
			===[[GERD]], [[Peptic ulcer disease]], [[Esophagitis]]===
			*40mg IV or PO daily

	==Pediatric Dosing==		==Pediatric Dosing==
			*<5yo: safety/efficacy not established
			*>5yo
			**15 kg to <40 kg: 20 mg PO qDay
			**40 kg or greater: 40 mg PO qDay

	==Special Populations<ref>Pantoprazole: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019. </ref>==		==Special Populations<ref>Pantoprazole: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019. </ref>==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: B
	*Lactation:		*Lactation:
	** Pantoprazole is present in breast milk		** Pantoprazole is present in breast milk
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	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:GI]]

2019-05-02T04:43:53Z

← Older revision		Revision as of 04:43, 2 May 2019
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	==Pediatric Dosing==		==Pediatric Dosing==

	==Special Populations==		==Special Populations<ref>Pantoprazole: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019. </ref>==
	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:
	*Lactation:		*Lactation:
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	==References==		==References==
	<references/>		<references/>
	* Pantoprazole: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019.
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

2019-04-02T19:13:33Z

References: added

← Older revision		Revision as of 19:13, 2 April 2019
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	==References==		==References==
	<references/>		<references/>
			* Pantoprazole: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019.
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

2019-04-02T19:12:43Z

Special Populations: added

← Older revision		Revision as of 19:12, 2 April 2019
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	*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:		*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]:
	*Lactation:		*Lactation:
			** Pantoprazole is present in breast milk
	*Renal Dosing		*Renal Dosing
	**Adult		**Adult
			*** No adjustment necessary
	**Pediatric		**Pediatric
			*** Not defined
	*Hepatic Dosing		*Hepatic Dosing
	**Adult		**Adult
			*** No adjustment necessary
	**Pediatric		**Pediatric
			*** Not defined

	==Contraindications==		==Contraindications==

2017-10-24T17:42:20Z

Common

2017-10-24T17:41:25Z

Serious

2017-10-24T17:39:47Z

Pharmacology

← Older revision		Revision as of 17:39, 24 October 2017
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	==Pharmacology==		==Pharmacology==
	*Half-life:		*Half-life: 1 hour
	*Metabolism:		*Metabolism: Hepatic - CYP450
	*Excretion:		*Excretion: Urine/Feces
	*Mechanism of Action:		*Mechanism of Action: inhibits gastric parietal cell H+/K+ ATPase

	==See Also==		==See Also==

2017-07-13T06:51:04Z