Phencyclidine toxicity - Revision history

Rossdonaldson1 at 18:53, 24 April 2024

2024-04-24T18:53:31Z

← Older revision		Revision as of 18:53, 24 April 2024
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	''Note: this page is about the drug phencyclidine. For the infection, see [[PCP pneumonia]]''		''Note: this page is about the drug phencyclidine. For the infection, see [[PCP pneumonia]]''

	==Background==		==Background==
	[[File:Phencyclidine (PCP).jpg\|thumb\|PCP in several forms.]]		[[File:Phencyclidine (PCP).jpg\|thumb\|PCP in several forms.]]

2021-12-02T18:26:08Z

Background

← Older revision		Revision as of 18:26, 2 December 2021
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	==Background==		==Background==
			[[File:Phencyclidine (PCP).jpg\|thumb\|PCP in several forms.]]
	*Also known as: PCP, "angel dust", "dippers", "supergrass", "whack", "rocket fuel"		*Also known as: PCP, "angel dust", "dippers", "supergrass", "whack", "rocket fuel"
	*Synthetic piperidine derivative, structurally similar to [[ketamine]]		*Synthetic piperidine derivative, structurally similar to [[ketamine]]
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	*Dissociative anesthetic		*Dissociative anesthetic
	*Smoked, ingested, or injected		*Smoked, ingested, or injected
	*Sometimes combined with tobacco, marijuana ("wet"), crack cocaine, or other drugs		*Sometimes combined with tobacco, [[marijuana]] ("wet"), crack [[cocaine]], or other drugs

	==Clinical Features==		==Clinical Features==

2020-11-14T13:46:11Z

Differential Diagnosis

2017-05-02T01:58:40Z

Background

← Older revision		Revision as of 01:58, 2 May 2017
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	*Synthetic piperidine derivative, structurally similar to [[ketamine]]		*Synthetic piperidine derivative, structurally similar to [[ketamine]]
	*NMDA inhibitor, at high doses, can also act as norepinepherine/dopamine reuptake inhibitor, and interact with opioid, acetylcholine, and voltage-gated ion channel receptors		*NMDA inhibitor, at high doses, can also act as norepinepherine/dopamine reuptake inhibitor, and interact with opioid, acetylcholine, and voltage-gated ion channel receptors
			*Dissociative anesthetic
	*Smoked, ingested, or injected		*Smoked, ingested, or injected
	*Sometimes combined with tobacco, marijuana ("wet"), crack cocaine, or other drugs		*Sometimes combined with tobacco, marijuana ("wet"), crack cocaine, or other drugs

2016-11-07T21:54:18Z

Evaluation

← Older revision		Revision as of 21:54, 7 November 2016
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	==Evaluation==		==Evaluation==
	*Usually clinical diagnosis		*Usually clinical diagnosis
	*UDS: false positive screens for PCP can result from [[dextromethorphan]], [[~~diphenydramine~~]], [[doxylamine]], [[ibuprofen]], [[meperidine]], [[tramadol]], [[venlafaxine]])		*UDS: false positive screens for PCP can result from [[dextromethorphan]], [[diphenhydramine]], [[doxylamine]], [[ibuprofen]], [[meperidine]], [[tramadol]], [[venlafaxine]])
	*Evaluate for dangerous effects of drug:		*Evaluate for dangerous effects of drug:
	**Occult trauma		**Occult trauma

2016-09-24T10:39:34Z

Evaluation

← Older revision		Revision as of 10:39, 24 September 2016
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	==Evaluation==		==Evaluation==
	*Usually clinical diagnosis		*Usually clinical diagnosis
	*UDS: false positive screens for PCP can result from dextromethorphan, diphenydramine, doxylamine, ibuprofen, meperidine, tramadol, venlafaxine)		*UDS: false positive screens for PCP can result from [[dextromethorphan]], [[diphenydramine]], [[doxylamine]], [[ibuprofen]], [[meperidine]], [[tramadol]], [[venlafaxine]])
	*Evaluate for dangerous effects of drug:		*Evaluate for dangerous effects of drug:
	**Occult trauma		**Occult trauma

2016-09-24T10:39:02Z

Evaluation

← Older revision		Revision as of 10:39, 24 September 2016
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	**End-organ damage due to [[hypertensive emergency]]		**End-organ damage due to [[hypertensive emergency]]
	*Evaluate for other causes of presentation (e.g. other drugs, infection, endocrine/metabolic disorders, other causes of [[AMS]])		*Evaluate for other causes of presentation (e.g. other drugs, infection, endocrine/metabolic disorders, other causes of [[AMS]])


	==Management==		==Management==

2016-09-24T10:38:36Z

Differential Diagnosis

2016-09-24T10:37:57Z

Background

← Older revision		Revision as of 10:37, 24 September 2016
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	==Background==		==Background==
	*~~aka~~ PCP, "angel dust", "dippers", "supergrass", "whack", "rocket fuel"		*Also known as: PCP, "angel dust", "dippers", "supergrass", "whack", "rocket fuel"
	*Synthetic piperidine derivative, structurally similar to [[ketamine]]		*Synthetic piperidine derivative, structurally similar to [[ketamine]]
	*NMDA inhibitor, at high doses, can also act as norepinepherine/dopamine reuptake inhibitor, and interact with opioid, acetylcholine, and voltage-gated ion channel receptors		*NMDA inhibitor, at high doses, can also act as norepinepherine/dopamine reuptake inhibitor, and interact with opioid, acetylcholine, and voltage-gated ion channel receptors

2016-09-22T14:37:01Z