https://wikem.org/w/index.php?action=history&feed=atom&title=Temazepam 2026-04-17T14:49:16Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Temazepam&diff=203208&oldid=prev 2019-01-14T04:43:02Z

<p>Creation of page</p> <p><b>New page</b></p><div>==Administration==<br /> *Type: [[Benzodiazepine]]<br /> *Dosage Forms: Cap 7.5mg, 15mg, 22.5mg, 30mg<br /> *Routes of Administration: Oral<br /> *Common Trade Names: Restoril<br /> <br /> ==Adult Dosing==<br /> ===[[Insomnia]]===<br /> *15mg PO qhs<br /> **Start 7.5mg PO qhs in elderly patients<br /> ===Sleep terrors===<br /> *15-30mg PO qhs<br /> <br /> ==Pediatric Dosing==<br /> Safety/efficacy not established in pediatric patients<br /> <br /> ==Special Populations==<br /> ===[[Drug pregnancy categories|Pregnancy Rating]]===<br /> *Consider alternatives during pregnancy<br /> *Risk of neonatal withdrawal symptoms and floppy infant syndrome<br /> <br /> ===Lactation risk===<br /> *May use low doses short-term when breastfeeding<br /> <br /> ===Renal Dosing===<br /> *Adult: No adjustment<br /> *Pediatric: Not defined<br /> <br /> ===Hepatic Dosing===<br /> *Adult: No adjustment<br /> *Pediatric: Not defined<br /> <br /> ==Contraindications==<br /> *Allergy to class/drug<br /> *Pregnancy<br /> *Avoid abrupt withdrawal with long term use<br /> <br /> ==Adverse Reactions==<br /> ===Serious===<br /> *[[Anaphylaxis]], [[angioedema]]<br /> *Respiratory depression<br /> *Dependency<br /> *[[Seizure]]<br /> *Suicidality<br /> *[[Tachycardia]], [[hypotension]], [[syncope]]<br /> <br /> ===Common===<br /> *Drowsiness, fatigue<br /> *[[Dizziness]]<br /> *[[Anxiety]], [[Amnesia]], confusion<br /> *Disinhibition<br /> *Dystonia. [[Dysarthria]], diplopia<br /> *Incontinence, constipation<br /> *[[Rash]]<br /> <br /> ==Pharmacology==<br /> *Half-life: 8.8h<br /> *Metabolism: Liver<br /> *Excretion: Urine 80-90%<br /> <br /> ==Mechanism of Action==<br /> *Binds to [[benzodiazepine]] receptors to enhance GABA effects<br /> <br /> ==Comments==<br /> <br /> <br /> ==See Also==<br /> [[Benzodiazepine]]<br /> <br /> ==References==<br /> &lt;references/&gt;<br /> <br /> [[Category:Pharmacology]]</div>

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