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	<id>https://wikem.org/w/index.php?action=history&amp;feed=atom&amp;title=Template%3ASuboxone_protocol</id>
	<title>Template:Suboxone protocol - Revision history</title>
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	<updated>2026-04-16T21:46:35Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikem.org/w/index.php?title=Template:Suboxone_protocol&amp;diff=374102&amp;oldid=prev</id>
		<title>Rossdonaldson1 at 19:46, 17 July 2024</title>
		<link rel="alternate" type="text/html" href="https://wikem.org/w/index.php?title=Template:Suboxone_protocol&amp;diff=374102&amp;oldid=prev"/>
		<updated>2024-07-17T19:46:20Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 19:46, 17 July 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;gt;=8&lt;/del&gt;:  give 4 to 8mg of [[Buprenorphine]], observe 30 to 45min&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;≥8&lt;/ins&gt;:  give 4 to 8mg of [[Buprenorphine]], observe 30 to 45min&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Redose if COWS remains &lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;gt;=8&lt;/del&gt;. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine).&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Redose if COWS remains &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;≥8&lt;/ins&gt;. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine).&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &amp;gt;8 for the standard buprenorphine induction.  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &amp;gt;8 for the standard buprenorphine induction.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Alternatively, you can prescribe consider unobserved home induction instructions available on paper &amp;lt;ref&amp;gt;A Guide for Patients Beginning Buprenorphine Treatment at Home https://medicine.yale.edu/edbup/quickstart/Home_Buprenorphine_Initiation_338574_42801_v1.pdf&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;A Patient’s Guide to Starting Buprenorphine at Home from ASAM https://www.asam.org/docs/default-source/education-docs/unobserved-home-induction-patient-guide.pdf&amp;lt;/ref&amp;gt; and app&amp;lt;ref&amp;gt;Buprenorphine Home Induction  Apple App Store https://apps.apple.com/us/app/buprenorphine-home-induction/id1449302173&amp;lt;/ref&amp;gt; &amp;lt;ref&amp;gt;Starting Buprenorphine from Google Play Store https://play.google.com/store/apps/details?id=com.amstonstudio.bup&amp;amp;hl=en_US&amp;amp;gl=US&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;**Alternatively, you can prescribe consider unobserved home induction instructions available on paper &amp;lt;ref&amp;gt;A Guide for Patients Beginning Buprenorphine Treatment at Home https://medicine.yale.edu/edbup/quickstart/Home_Buprenorphine_Initiation_338574_42801_v1.pdf&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;A Patient’s Guide to Starting Buprenorphine at Home from ASAM https://www.asam.org/docs/default-source/education-docs/unobserved-home-induction-patient-guide.pdf&amp;lt;/ref&amp;gt; and app&amp;lt;ref&amp;gt;Buprenorphine Home Induction  Apple App Store https://apps.apple.com/us/app/buprenorphine-home-induction/id1449302173&amp;lt;/ref&amp;gt; &amp;lt;ref&amp;gt;Starting Buprenorphine from Google Play Store https://play.google.com/store/apps/details?id=com.amstonstudio.bup&amp;amp;hl=en_US&amp;amp;gl=US&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Rossdonaldson1</name></author>
	</entry>
	<entry>
		<id>https://wikem.org/w/index.php?title=Template:Suboxone_protocol&amp;diff=374000&amp;oldid=prev</id>
		<title>Ostermayer at 09:29, 4 July 2024</title>
		<link rel="alternate" type="text/html" href="https://wikem.org/w/index.php?title=Template:Suboxone_protocol&amp;diff=374000&amp;oldid=prev"/>
		<updated>2024-07-04T09:29:40Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 09:29, 4 July 2024&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l1&quot;&gt;Line 1:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Line 1:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &amp;gt;=8: 4 to 8mg, observe 30 to 45min&lt;del style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;, redose &lt;/del&gt;if COWS remains &amp;gt;=8. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine).&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &amp;gt;=8: &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt; give &lt;/ins&gt;4 to 8mg &lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;of [[Buprenorphine]]&lt;/ins&gt;, observe 30 to 45min&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &amp;gt;8 for the standard buprenorphine induction. Alternatively, you can prescribe consider unobserved home induction instructions available on paper &amp;lt;ref&amp;gt;A Guide for Patients Beginning Buprenorphine Treatment at Home https://medicine.yale.edu/edbup/quickstart/Home_Buprenorphine_Initiation_338574_42801_v1.pdf&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;A Patient’s Guide to Starting Buprenorphine at Home from ASAM https://www.asam.org/docs/default-source/education-docs/unobserved-home-induction-patient-guide.pdf&amp;lt;/ref&amp;gt; and app&amp;lt;ref&amp;gt;Buprenorphine Home Induction  Apple App Store https://apps.apple.com/us/app/buprenorphine-home-induction/id1449302173&amp;lt;/ref&amp;gt; &amp;lt;ref&amp;gt;Starting Buprenorphine from Google Play Store https://play.google.com/store/apps/details?id=com.amstonstudio.bup&amp;amp;hl=en_US&amp;amp;gl=US&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;**Redose &lt;/ins&gt;if COWS remains &amp;gt;=8. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine).&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &amp;gt;8 for the standard buprenorphine induction.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;**&lt;/ins&gt;Alternatively, you can prescribe consider unobserved home induction instructions available on paper &amp;lt;ref&amp;gt;A Guide for Patients Beginning Buprenorphine Treatment at Home https://medicine.yale.edu/edbup/quickstart/Home_Buprenorphine_Initiation_338574_42801_v1.pdf&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;A Patient’s Guide to Starting Buprenorphine at Home from ASAM https://www.asam.org/docs/default-source/education-docs/unobserved-home-induction-patient-guide.pdf&amp;lt;/ref&amp;gt; and app&amp;lt;ref&amp;gt;Buprenorphine Home Induction  Apple App Store https://apps.apple.com/us/app/buprenorphine-home-induction/id1449302173&amp;lt;/ref&amp;gt; &amp;lt;ref&amp;gt;Starting Buprenorphine from Google Play Store https://play.google.com/store/apps/details?id=com.amstonstudio.bup&amp;amp;hl=en_US&amp;amp;gl=US&amp;lt;/ref&amp;gt;.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*If sublingual tablets/films unavailable then intravenous/intramuscular formulation (dose 0.3-0.9 mg every 6-12 hours) has been used for opioid withdrawal in the ED&amp;lt;ref&amp;gt;Berg ML, et. al. Evaluation of the use of buprenorphine for opioid withdrawal in an emergency department. Drug Alcohol Depend. 2007 Jan 12;86(2-3):239-44. https://doi.org/10.1016/j.drugalcdep.2006.06.014. Epub 2006 Aug 22. PMID: 16930865.&amp;lt;/ref&amp;gt; and hospitalized&amp;lt;ref&amp;gt;Welsh CJ, Suman M, Cohen A, et al. The use of intravenous buprenorphine for the treatment of opioid withdrawal in medically ill hospitalized patients. Am J Addict. 2002;11(2):135-40 https://doi.org/10.1080/105500490290087901&amp;lt;/ref&amp;gt; patients.  &lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;*If sublingual tablets/films unavailable then intravenous/intramuscular formulation (dose 0.3-0.9 mg every 6-12 hours) has been used for opioid withdrawal in the ED&amp;lt;ref&amp;gt;Berg ML, et. al. Evaluation of the use of buprenorphine for opioid withdrawal in an emergency department. Drug Alcohol Depend. 2007 Jan 12;86(2-3):239-44. https://doi.org/10.1016/j.drugalcdep.2006.06.014. Epub 2006 Aug 22. PMID: 16930865.&amp;lt;/ref&amp;gt; and hospitalized&amp;lt;ref&amp;gt;Welsh CJ, Suman M, Cohen A, et al. The use of intravenous buprenorphine for the treatment of opioid withdrawal in medically ill hospitalized patients. Am J Addict. 2002;11(2):135-40 https://doi.org/10.1080/105500490290087901&amp;lt;/ref&amp;gt; patients.  &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br/&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[File:Buprenorphine in ED.png|thumb|NIH National Institute on Drug Abuse ED Buprenorphine algorithm&amp;lt;ref&amp;gt;https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/algorithm.pdf&amp;lt;/ref&amp;gt;]]&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;[[File:Buprenorphine in ED.png|thumb|NIH National Institute on Drug Abuse ED Buprenorphine algorithm&amp;lt;ref&amp;gt;https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/algorithm.pdf&amp;lt;/ref&amp;gt;]]&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Ostermayer</name></author>
	</entry>
	<entry>
		<id>https://wikem.org/w/index.php?title=Template:Suboxone_protocol&amp;diff=373996&amp;oldid=prev</id>
		<title>Ostermayer: Created page with &quot;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &gt;=8: 4 to 8mg, observe 30 to 45min, redose if COWS remains &gt;=8. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine). *For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &gt;8 for the standard buprenorphine induction. Alternatively, you can prescribe...&quot;</title>
		<link rel="alternate" type="text/html" href="https://wikem.org/w/index.php?title=Template:Suboxone_protocol&amp;diff=373996&amp;oldid=prev"/>
		<updated>2024-07-04T09:23:52Z</updated>

		<summary type="html">&lt;p&gt;Created page with &amp;quot;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &amp;gt;=8: 4 to 8mg, observe 30 to 45min, redose if COWS remains &amp;gt;=8. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine). *For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &amp;gt;8 for the standard buprenorphine induction. Alternatively, you can prescribe...&amp;quot;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;*For [https://www.mdcalc.com/cows-score-opiate-withdrawal Clinical Opioid Withdrawal Scale] (COWS) &amp;gt;=8: 4 to 8mg, observe 30 to 45min, redose if COWS remains &amp;gt;=8. Then discharge home with 16 mg a day to bridge until follow-up (an X-waiver is no longer required to prescribe buprenorphine).&lt;br /&gt;
*For Clinical Opioid Withdrawal Scale (COWS) 0-7: Consider observing the patient until their COWS score is &amp;gt;8 for the standard buprenorphine induction. Alternatively, you can prescribe consider unobserved home induction instructions available on paper &amp;lt;ref&amp;gt;A Guide for Patients Beginning Buprenorphine Treatment at Home https://medicine.yale.edu/edbup/quickstart/Home_Buprenorphine_Initiation_338574_42801_v1.pdf&amp;lt;/ref&amp;gt;&amp;lt;ref&amp;gt;A Patient’s Guide to Starting Buprenorphine at Home from ASAM https://www.asam.org/docs/default-source/education-docs/unobserved-home-induction-patient-guide.pdf&amp;lt;/ref&amp;gt; and app&amp;lt;ref&amp;gt;Buprenorphine Home Induction  Apple App Store https://apps.apple.com/us/app/buprenorphine-home-induction/id1449302173&amp;lt;/ref&amp;gt; &amp;lt;ref&amp;gt;Starting Buprenorphine from Google Play Store https://play.google.com/store/apps/details?id=com.amstonstudio.bup&amp;amp;hl=en_US&amp;amp;gl=US&amp;lt;/ref&amp;gt;. &lt;br /&gt;
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*If sublingual tablets/films unavailable then intravenous/intramuscular formulation (dose 0.3-0.9 mg every 6-12 hours) has been used for opioid withdrawal in the ED&amp;lt;ref&amp;gt;Berg ML, et. al. Evaluation of the use of buprenorphine for opioid withdrawal in an emergency department. Drug Alcohol Depend. 2007 Jan 12;86(2-3):239-44. https://doi.org/10.1016/j.drugalcdep.2006.06.014. Epub 2006 Aug 22. PMID: 16930865.&amp;lt;/ref&amp;gt; and hospitalized&amp;lt;ref&amp;gt;Welsh CJ, Suman M, Cohen A, et al. The use of intravenous buprenorphine for the treatment of opioid withdrawal in medically ill hospitalized patients. Am J Addict. 2002;11(2):135-40 https://doi.org/10.1080/105500490290087901&amp;lt;/ref&amp;gt; patients. &lt;br /&gt;
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[[File:Buprenorphine in ED.png|thumb|NIH National Institute on Drug Abuse ED Buprenorphine algorithm&amp;lt;ref&amp;gt;https://d14rmgtrwzf5a.cloudfront.net/sites/default/files/algorithm.pdf&amp;lt;/ref&amp;gt;]]&lt;/div&gt;</summary>
		<author><name>Ostermayer</name></author>
	</entry>
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