https://wikem.org/w/index.php?action=history&feed=atom&title=Ursodiol 2026-04-18T02:05:38Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Ursodiol&diff=229773&oldid=prev 2019-09-23T23:15:03Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 23:15, 23 September 2019</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Special Populations==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Special Populations==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===[[Drug pregnancy categories|Pregnancy Rating]]===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===[[Drug pregnancy categories|Pregnancy Rating]]===</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>*<del style="font-weight: bold; text-decoration: none;">May </del>use during pregnancy</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>*<ins style="font-weight: bold; text-decoration: none;">Category B: may </ins>use during pregnancy</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Lactation risk===</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>===Lactation risk===</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l84">Line 84:</td> <td colspan="2" class="diff-lineno">Line 84:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Pharmacology]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Pharmacology]]</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[Category:GI]]</ins></div></td></tr> </table>

ClaireLewis https://wikem.org/w/index.php?title=Ursodiol&diff=193888&oldid=prev 2018-09-17T06:47:00Z

<p>Creation of page</p> <p><b>New page</b></p><div>==Administration==<br /> *Type: Hepatobiliary<br /> *Dosage Forms: Cap: 300mg; Tab: 250mg, 500mg<br /> *Routes of Administration: Oral<br /> *Common Trade Names: Actigall, Urso 250, Urso Forte<br /> <br /> ==Adult Dosing==<br /> ===Gallstone dissolution===<br /> *8-10 mg/kg/day PO divided qd-tid<br /> ===Primary biliary cirrhosis===<br /> *13-15 mg/kg/day PO divided BID-TID<br /> ===[[Primary sclerosing cholangitis]]===<br /> *25-30 mg/kg/day PO divided qd-qid<br /> ===Steatohepatitis, non-alcoholic===<br /> *10-15 mg/kg/day PO divided qd-qid<br /> <br /> ==Pediatric Dosing==<br /> ===[[Biliary atresia]]===<br /> *&lt; 1mo<br /> **20-30 mg/kg/day PO divided bid<br /> *&gt; 1mo<br /> **10-30 mg/kg/day PO divided bid<br /> ===[[Pruritus]], cholestasis-associated===<br /> *&gt; 1mo<br /> **15-30 mg/kg/day<br /> <br /> ==Special Populations==<br /> ===[[Drug pregnancy categories|Pregnancy Rating]]===<br /> *May use during pregnancy<br /> <br /> ===Lactation risk===<br /> *May use while breastfeeding<br /> <br /> ===Renal Dosing===<br /> *Adult: Not defined<br /> *Pediatric: Dose adjustment may be required, but specific guidelines not defined<br /> <br /> ===Hepatic Dosing===<br /> *Adult: Not defined<br /> *Pediatric: Dose adjustment may be required, but specific guidelines not defined<br /> <br /> ==Contraindications==<br /> *Allergy to class/drug<br /> *Unremitting [[acute cholecystitis]]<br /> *[[Cholangitis]], acute<br /> *Biliary obstruction<br /> *[[Gallstone pancreatitis]]<br /> *Biliary-GI fistula<br /> *Gallstones, calcified cholesterol<br /> *Gallstones, radiopaque<br /> *Gallstones, radiolucent bile pigment<br /> <br /> ==Adverse Reactions==<br /> ===Serious===<br /> *[[Leukopenia]], [[thrombocytopenia]]<br /> *Hypersensitivity reaction<br /> *[[Anaphylaxis]]<br /> *[[Jaundice]], LFTs elevated<br /> <br /> ===Common===<br /> *[[Diarrhea]], [[constipation]]<br /> *[[Headache]], [[dizziness]]<br /> *[[nausea]], dyspepsia, [[vomiting]], flatulence<br /> *Back pain, MSK pain<br /> *[[Alopecia]], [[rash]], [[pruritus]]<br /> <br /> ==Pharmacology==<br /> *Half-life: Unknown<br /> *Metabolism: Liver, GI tract<br /> *Excretion: Feces primarily, urine<br /> <br /> ==Mechanism of Action==<br /> *Decreases cholesterol synthesis, secretion, and absorption<br /> *Alters bile cholesterol composition<br /> <br /> ==Comments==<br /> <br /> <br /> ==See Also==<br /> <br /> <br /> ==References==<br /> &lt;references/&gt;<br /> <br /> [[Category:Pharmacology]]</div>

Jonwarren