Voriconazole - Revision history

Danbot: Restore original dosing content alongside dynamic SMW tables

2026-03-20T02:38:59Z

Restore original dosing content alongside dynamic SMW tables

← Older revision		Revision as of 02:38, 20 March 2026
Line 6:		Line 6:

	==Adult Dosing==		==Adult Dosing==
			*200-400mg PO BID or 4-6mg IV BID


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Voriconazole]] [[Has Population::Adult]]		{{#ask: [[Has DrugName::Voriconazole]] [[Has Population::Adult]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

	==Pediatric Dosing==		==Pediatric Dosing==
			*Children >12 yo: same as adult dosing


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Voriconazole]] [[Has Population::Pediatric]]		{{#ask: [[Has DrugName::Voriconazole]] [[Has Population::Pediatric]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

Danbot: Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

2026-03-20T01:53:39Z

Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

@@ Line 6: / Line 6: @@
 ==Adult Dosing==
-*200-400mg PO BID or 4-6mg IV BID
+===Indications by Disease===
 ==Pediatric Dosing==
-*Children >12 yo: same as adult dosing
+===Indications by Disease===
 ==Special Populations==

Elcatracho: /* Administration */

2021-03-08T03:26:57Z

Administration

← Older revision		Revision as of 03:26, 8 March 2021
Line 3:		Line 3:
	*Dosage Forms:		*Dosage Forms:
	*Routes of Administration: IV, PO		*Routes of Administration: IV, PO
	*Common Trade Names:		*Common Trade Names: Vfend

	==Adult Dosing==		==Adult Dosing==

Elcatracho: /* See Also */

2021-03-08T03:26:17Z

ClaireLewis: /* References */

2019-09-23T23:29:09Z

References

← Older revision		Revision as of 23:29, 23 September 2019
Line 56:		Line 56:
	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:ID]]

Neil.m.young: Text replacement - "* " to "*"

2016-10-27T15:44:29Z

Text replacement - "* " to "*"

← Older revision		Revision as of 15:44, 27 October 2016
Line 46:		Line 46:

	==Mechanism of Action==		==Mechanism of Action==
	* Triazole antifungal: inhibits synthesis of fungal cell wall ergosterol		*Triazole antifungal: inhibits synthesis of fungal cell wall ergosterol

	==Comments==		==Comments==

Rossdonaldson1: Text replacement - "Pancreatitis" to "Pancreatitis"

2016-09-25T22:19:01Z

Text replacement - "*Pancreatitis" to "*Pancreatitis"

← Older revision		Revision as of 22:19, 25 September 2016
Line 29:		Line 29:
	*Renal failure		*Renal failure
	*Toxic encephalopathy		*Toxic encephalopathy
	*Pancreatitis		*[[Pancreatitis]]
	*Optic neuritis		*Optic neuritis
	===Common===		===Common===

ClaireLewis: Created page with "==Administration== Type: Antifungal (Candida, mycoses, Aspergillosis) Dosage Forms: Routes of Administration: IV, PO Common Trade Names: ==Adult Dosing== *20..."

2016-09-12T05:15:20Z

Created page with "==Administration== *Type: Antifungal (Candida, mycoses, Aspergillosis) *Dosage Forms: *Routes of Administration: IV, PO *Common Trade Names: ==Adult Dosing== *20..."

New page

==Administration==
*Type: [[Antifungal]] ([[Candida]], mycoses, [[Aspergillosis]])
*Dosage Forms:
*Routes of Administration: IV, PO
*Common Trade Names:

==Adult Dosing==
*200-400mg PO BID or 4-6mg IV BID

==Pediatric Dosing==
*Children >12 yo: same as adult dosing

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: D
*[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out
*Renal dosing: PO preferred, no adjustement to dose
*Hepatic dosing: mild-moderate impairment- reduce dose. Severe: avoid using

==Contraindications==
*Allergy to class/drug
*Concomitant use of carbamazepine or CYP3A4 substrates, ritonavir, ergots, barbiturates, rifampin, sirolimus, or St. John's Wort

==Adverse Reactions==
===Serious===
*Prolonged QT, dysrhythmias, cardiac arrest
*Erythema multiforme, SJS, TEN
*Malignant melanoma, squamous cell carcinoma
*Hepatotoxicity
*Renal failure
*Toxic encephalopathy
*Pancreatitis
*Optic neuritis
===Common===
*Peripheral edema
*Rash
*Nausea/vomiting, diarrhea
*Headache
*Visual disturbances
*Hallucinations
*Fever

==Pharmacology==
*Half-life: Dose dependant, non-linear pharmacokinetics
*Metabolism: CYP2C19, CYP2C9 and CYP3A4
*Excretion: Renal

==Mechanism of Action==
* Triazole antifungal: inhibits synthesis of fungal cell wall ergosterol

==Comments==

==See Also==
*[[Antifungals]]

==References==
<references/>
[[Category:Pharmacology]]

← Older revision		Revision as of 03:26, 8 March 2021
Line 52:		Line 52:
	==See Also==		==See Also==
	*[[Antifungals]]		*[[Antifungals]]
			*[[Fungal infections]]

	==References==		==References==