Cocaine: Difference between revisions

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==Adverse Reactions==
==Adverse Reactions==
*Acute
*[[Cocaine-associated chest pain]]
**[[Cocaine-associated chest pain]]
*Sympathomimetic qualities
**Sympathomimetic qualities
**Tachycardia
***Tachycardia
**Fever
***Fever
**Agitation
***Agitation
**Diaphoresis
***Diaphoresis
**Pulmonary Complications:
***"Crack lung"<ref>Forrester, J. M., Steele, A. W., Waldron, J. A. and Parsons, P. E. (1990) ‘Crack Lung: An Acute Pulmonary Syndrome with a Spectrum of Clinical and Histopathologic Findings’, American Review of Respiratory Disease, 142(2), pp. 462–467. doi: 10.1164/ajrccm/142.2.462.</ref>
***Diffuse alveolar hemorrhage<ref>Ettinger, N. A. and Albin, R. J. (1989) ‘A review of the respiratory effects of smoking cocaine’, The American Journal of Medicine, 87(6), pp. 664–668. doi: 10.1016/s0002-9343(89)80401-2.</ref>
***[[ARDS]]
***Acute eosinophilic pneumonia
***[[Pneumothorax]]
***[[Pneumomediastinum]]
***Thermal epiglottitis - hot cocaine
*Chronic
**Atherosclerosis
**Cardiomyopathy
**Nasal Septum damage
**Up to 70% of US cocaine tainted with [[levamisole]], potentially leading to [[neutropenia]], [[vasculitis]]
 


==Pharmacology==
==Pharmacology==

Revision as of 20:04, 18 February 2017

This page is for the drug cocaine; for clinical effects see cocaine toxicity

Administration

  • Type:
  • Dosage Forms:
  • Routes of Administration:
  • Common Trade Names:

Adult Dosing

Pediatric Dosing

Special Populations

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug

Adverse Reactions

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

  • Blocks reuptake of serotonin, dopamine and norepinephrine
  • Anesthetic effects achieved through sodium channel blockade

Comments

See Also

References


See Also

References

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