Endophthalmitis: Difference between revisions

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==Background==
==Background==
*Inflammation (usually infectious) of the aqueous or vitreous humor
*Inflammation (usually infectious) of the deep eye structures (aqueous and vitreus chambers)
**Staphylococcus, Streptococcus, Bacillus cereus
*Frequently leads to loss of vision (ocular emergency)
*Frequently leads to loss of vision (ocular emergency)


==Causes==
==Causes==
#Cataract surgery
*Cataract surgery
#Penetrating trauma
**Usually within 6 weeks
#Extension of keratitis
*[[Globe Rupture]]
#Hematogenous spread
**Penetrating eye trauma more at risk than blunt eye trauma
*Foreign body
*Extension of keratitis
*Hematogenous spread/endogenous (rare)


==Clinical Features==
==Clinical Features==
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##Hypopyon
##Hypopyon
##Uveitis
##Uveitis
==Work-Up==
*Visual Acuity
*Inspect of lid, cornea, sclera
*Slit lamp exam
*Intraocular pressure
**After exclusion of [[Globe Rupture]]
*Bloodwork (CBC, ESR, ) only if considering endogenous endophthalmitis
*Ultrasound to look for alternative diagnosis
**After exclusion of [[Globe Rupture]]
==DDx==
*Sterile postoperative inflammation
*[[Red Eye (Unilateral)]]
*[[Corneal Abrasion and Foreign Body]]
*[[Uveitis]]
*[[Vitreous Hemorrhage]]


==Treatment==
==Treatment==
#Emergent ophtho consult (for intravitreal abx)
*Emergent ophtho consult (for gram stain/culture and definitive treatment of intravitreal abx)
#Vancomycin 1gm IV q12hr + ceftazidime 3gm IV q8hr
*Systemic antibiotics for endogenous endophthalmitis (rare cause)
**Systemic antibiotics for other etiologies is controversial
**Antibiotic prophylaxis in [[Globe Rupture]] reduces incidence of endophthalmitis to <1%


==Disposition==
==Disposition==
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==See Also==
==See Also==
[[Eye Algorithm (Main)]]
[[Eye Algorithm (Main)]]
[[Globe Rupture]]


==Source==
==Source==
Tintinalli
Tintinalli
Rosen's
UpToDate


[[Category:Ophtho]]
[[Category:Ophtho]]

Revision as of 21:40, 12 September 2013

Background

  • Inflammation (usually infectious) of the deep eye structures (aqueous and vitreus chambers)
    • Staphylococcus, Streptococcus, Bacillus cereus
  • Frequently leads to loss of vision (ocular emergency)

Causes

  • Cataract surgery
    • Usually within 6 weeks
  • Globe Rupture
    • Penetrating eye trauma more at risk than blunt eye trauma
  • Foreign body
  • Extension of keratitis
  • Hematogenous spread/endogenous (rare)

Clinical Features

  1. Headache
  2. Eye pain
  3. Photophobia
  4. Vision loss
  5. Ocular discharge
  6. May also see:
    1. Conjunctival/scleral injection
    2. Chemosis
    3. Hypopyon
    4. Uveitis

Work-Up

  • Visual Acuity
  • Inspect of lid, cornea, sclera
  • Slit lamp exam
  • Intraocular pressure
  • Bloodwork (CBC, ESR, ) only if considering endogenous endophthalmitis
  • Ultrasound to look for alternative diagnosis

DDx

Treatment

  • Emergent ophtho consult (for gram stain/culture and definitive treatment of intravitreal abx)
  • Systemic antibiotics for endogenous endophthalmitis (rare cause)
    • Systemic antibiotics for other etiologies is controversial
    • Antibiotic prophylaxis in Globe Rupture reduces incidence of endophthalmitis to <1%

Disposition

  • Admit

See Also

Eye Algorithm (Main) Globe Rupture

Source

Tintinalli Rosen's UpToDate