Ataxia (peds): Difference between revisions

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===Background===
==Background==
*any disturbance in coordination of movement  
*any disturbance in coordination of movement  
*most cases in ED will be acute (<72h), but can also be episodic or chronic  
*most cases in ED will be acute (<72h), but can also be episodic or chronic  
*etiology usually benign in previously healthy child  
*etiology usually benign in previously healthy child  
*most cases will be postinfectious cerebellitis, drug ingestion, or guillain barre
*most cases will be postinfectious cerebellitis, drug ingestion, or [[Guillain Barre]]


===Clinical Features===
==Clinical Features==
*unsteady gait in all cases  
*unsteady gait in all cases  
*postinfectious cerebellitis:&nbsp;1-3 wks post URI&nbsp;like illness or immunization, truncal ataxia and gait instability, normal mental status, normal vitals, ONLY&nbsp;ataxia  
*postinfectious cerebellitis 1-3 wks post URI like illness or immunization, truncal ataxia and gait instability, normal mental status, normal vitals, ONLY ataxia  
*guillain barre:&nbsp;extremity ataxia more than truncal ataxia, areflexia or hyporeflexia, respiratory failure&nbsp;possible  
*[[Guillain Barre]] extremity ataxia more than truncal ataxia, areflexia or hyporeflexia, respiratory failure possible  
*drug ingestion:&nbsp;altered mental status, eye findings (nystagmus)  
*drug ingestion altered mental status, eye findings (nystagmus)  
*intracranial mass:&nbsp;headache, vomiting, gradual onset, visual changes,&nbsp;papilledema, focal neuro deficits  
*intracranial mass headache, vomiting, gradual onset, visual changes, papilledema, focal neuro deficits  
*meningitis/encephalitis:&nbsp;fever, meningismus, bulging fontanelle, rash, altered mental status, seizure&nbsp;
*[[Meningitis]]/[[Encephalitis]] fever, meningismus, bulging fontanelle, rash, altered mental status, seizure&nbsp;


===DDx===
==DDx==
*postinfectious cerebellitis (acute cerebellar ataxia)  
*postinfectious cerebellitis (acute cerebellar ataxia)  
*drug ingestion/ toxin exposure (anticonvulsants, antihistamines, benzos, alcohol, dextromethorphan, others)  
*drug ingestion/ toxin exposure (anticonvulsants, antihistamines, benzos, alcohol, dextromethorphan, others)  
*Guillain Barre syndrome  
*[[Guillain Barre]] syndrome  
*hypoglycemia
*[[Hypoglycemia]]
*post vaccination (varicella)  
*post vaccination (varicella)  
*encephalitis/meningitis
*[[Encephalitis]]/[[Meningitis]]
*intracranial mass lesion  
*intracranial mass lesion  
*hydrocephalus  
*hydrocephalus  
*intracranial bleed
*[[Intracranial Bleed]]
*stroke
*[[Stroke]]
*vertebrobasilar dissection  
*vertebrobasilar dissection  
*migraine  
*migraine  
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*epilepsy
*epilepsy


===Workup===
==Workup==
*exam  
*exam  
*tox screen, alcohol level  
*tox screen, alcohol level  
*accuchek  
*accuchek  
*drug levels as indicated (ex. antiepileptic level if possible ingestion)  
*drug levels as indicated (ex. antiepileptic level if possible ingestion)  
*head CT if concern for trauma or mass lesion  
*[[Head CT]] if concern for trauma or mass lesion  
*LP&nbsp;in most cases unless etiology is known  
*[[Lumbar Puncture]] in most cases unless etiology is known  
*EEG if poss sz related
*EEG if poss [[Seizure|seizure]] related


===Treatment===  
==Treatment==
*most postinfectious cerebellitis self limited, resolve within 3 months without sequelae  
*most postinfectious cerebellitis self limited, resolve within 3 months without sequelae  
*tox ingestion: supportive. social work or DCFS as indicated  
*tox ingestion: supportive. social work or DCFS as indicated  
*guillain barre:&nbsp;admit for IVIG, observation of respiratory status  
*[[Guillain Barre]] admit for IVIG, observation of respiratory status  
*meningitis/encephalitis:&nbsp;admit, IV abx, see meningitis section  
*[[Meningitis]]/[[Encephalitis]] admit, IV abx, see meningitis section  
*intracranial mass:&nbsp;NSG&nbsp;consultation
*intracranial mass: neurosurgery consultation


===Disposition===
==Disposition==
*consider d/c&nbsp;home mildly symptomatic, well appearing child with hx and exam c/w postinfectious cerebellitis with excellent follow-up (give injury prevention precautions)  
*consider d/c home mildly symptomatic, well appearing child with hx and exam c/w postinfectious cerebellitis with excellent follow-up (give injury prevention precautions)  
*otherwise, admission indicated for further workup, observation
*otherwise, admission indicated for further workup, observation


===Source===
==Source==
Harwood-Nuss  
Harwood-Nuss  


[[Category:Peds]]
[[Category:Peds]]
[[Category:Neuro]]
[[Category:Neuro]]

Revision as of 06:46, 18 December 2013

Background

  • any disturbance in coordination of movement
  • most cases in ED will be acute (<72h), but can also be episodic or chronic
  • etiology usually benign in previously healthy child
  • most cases will be postinfectious cerebellitis, drug ingestion, or Guillain Barre

Clinical Features

  • unsteady gait in all cases
  • postinfectious cerebellitis 1-3 wks post URI like illness or immunization, truncal ataxia and gait instability, normal mental status, normal vitals, ONLY ataxia
  • Guillain Barre extremity ataxia more than truncal ataxia, areflexia or hyporeflexia, respiratory failure possible
  • drug ingestion altered mental status, eye findings (nystagmus)
  • intracranial mass headache, vomiting, gradual onset, visual changes, papilledema, focal neuro deficits
  • Meningitis/Encephalitis fever, meningismus, bulging fontanelle, rash, altered mental status, seizure 

DDx

  • postinfectious cerebellitis (acute cerebellar ataxia)
  • drug ingestion/ toxin exposure (anticonvulsants, antihistamines, benzos, alcohol, dextromethorphan, others)
  • Guillain Barre syndrome
  • Hypoglycemia
  • post vaccination (varicella)
  • Encephalitis/Meningitis
  • intracranial mass lesion
  • hydrocephalus
  • Intracranial Bleed
  • Stroke
  • vertebrobasilar dissection
  • migraine
  • vasculitis
  • paraneoplastic syndrome
  • epilepsy

Workup

  • exam
  • tox screen, alcohol level
  • accuchek
  • drug levels as indicated (ex. antiepileptic level if possible ingestion)
  • Head CT if concern for trauma or mass lesion
  • Lumbar Puncture in most cases unless etiology is known
  • EEG if poss seizure related

Treatment

  • most postinfectious cerebellitis self limited, resolve within 3 months without sequelae
  • tox ingestion: supportive. social work or DCFS as indicated
  • Guillain Barre admit for IVIG, observation of respiratory status
  • Meningitis/Encephalitis admit, IV abx, see meningitis section
  • intracranial mass: neurosurgery consultation

Disposition

  • consider d/c home mildly symptomatic, well appearing child with hx and exam c/w postinfectious cerebellitis with excellent follow-up (give injury prevention precautions)
  • otherwise, admission indicated for further workup, observation

Source

Harwood-Nuss