Neuroblastoma (peds): Difference between revisions
| Line 19: | Line 19: | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
*[[Wilms tumor]] | *[[Wilms tumor]] | ||
*Other adrenal gland tumor | |||
==Evaluation== | ==Evaluation== | ||
Revision as of 19:47, 7 October 2018
Background
- Arises from primitive ganglion cells of sympathetic nervous system
- Most common neoplasm in 1st yr of life
- May arise anywhere along sympathetic nervous system
- Adrenal gland (40%)
- Abdomen (25%)
- Chest (15%)
Clinical Features
- Depends on location
- Large, painless abdominal mass
- Compression of bowel/bladder
- Horner syndrome
- Spinal cord compression
- Opsoclonus-myoclonus
- Highly associated with neuroblastoma
- Neutropenia/pancytopenia suggests bone marrow involvement
Differential Diagnosis
- Wilms tumor
- Other adrenal gland tumor
Evaluation
Management
- Admssion for tumor biopsy