Imipenem/Cilastatin

General

• Type: Carbapenems
• Dosage Forms:
• Common Trade Names:

Adult Dosing

General

• Fully-susceptible organisms: 500mg IV q6 hours
• Moderately-susceptible organisms: 1g IV q6-8 hours
• Max: Lower of 50 mg/kg or 4 g/day

Pediatric Dosing

General

• 60-100 mg/kg/day IV divided q6 hours
• First Dose: 10-16.6 mg/kg IV x 1
• Max: 4000 mg/day

Special Populations

• Pregnancy: C
• Lactation: Use caution
• Renal Dosing
  • Adult
  • Pediatric
• Hepatic Dosing
  • Adult
  • Pediatric

Contraindications

• Allergy to class/drug

Pharmacology

• Half-life:
• Metabolism:
• Excretion:
• Mechanism of Action:

See Also

• Antibiotics (Main)