Babesiosis: Difference between revisions
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==Treatment== | ==Treatment== | ||
*2 drug regimen for 7-10 days | *2 drug regimen for 7-10 days | ||
===[[ | ===Option 1=== | ||
*Atovaquone (750mg BID) and [[Azithromycin]] (500-1000mg on first day, 250-1000mg on subsequent days) | |||
===Option 2=== | |||
[[Clindamycin]] | |||
{{Babesiosis Clindamycin Adult}} | {{Babesiosis Clindamycin Adult}} | ||
==See Also== | ==See Also== | ||
Revision as of 17:22, 18 June 2014
Background
- Spread by the deer tick (Ixodes scapularis)
- People often unaware they are bitten
- Natural reservior is the white footed mouse
- Endemic in US, Europe, parts of Russia and China
- Babesia Microti is pathogen in US
Symptoms
- Fever, hemolytic anemia, chills, thrombocytopenia, DIC
- More severe disease in immunocompromized patients (HIV, Elderly, Asplenic)
Diagnosis
- Peripheral blood smear
- Shows intracellular parasites
- Maltese Cross sign
- May need large smear as parasitemia can be as low as 1%
- Can often be confused for malaria parasites
- Shows intracellular parasites
Treatment
- 2 drug regimen for 7-10 days
Option 1
- Atovaquone (750mg BID) and Azithromycin (500-1000mg on first day, 250-1000mg on subsequent days)
Option 2
- Clindamycin 600mg PO q8hrs x 7-10 days (or 300-600mg IV q6hrs)
- Give with Quinine 650mg TID