Xylazine toxicity: Difference between revisions
(Created page with "==Background== *analogue of clonidine and agonist at alpha 2 adrenergic receptor *used for sedation, anesthesia, muscle relaxation and analgesia in animals *used as drug of ab...") |
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==Background== | ==Background== | ||
* | *Analogue of [[clonidine]] and agonist at [[alpha-2 agonists|alpha 2 adrenergic receptor]] | ||
* | *Veterinary sedative, anesthetic, analgesic, and muscle relaxant | ||
* | *Human drug of abuse, usually as drug adulterant | ||
==Clinical Features== | ==Clinical Features== | ||
* | *[[Bradycardia]] | ||
* | *[[Respiratory depression]] | ||
* | *[[Hypotension]] | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
* | *See [[Bradycardia]], [[Hypotension]] | ||
{{Sedatve/hypnotic toxicity types}} | |||
==Evaluation== | ==Evaluation== | ||
*Evaluate for alternate etiologies | |||
*Clinical diagnosis | |||
==Management== | ==Management== | ||
* | *Supportive: address airway/respiratory drive/blood pressure, [[atropine]] for bradycardia | ||
==Disposition== | ==Disposition== | ||
* | *Admit if not back to baseline | ||
==See Also== | ==See Also== | ||
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https://www.ncbi.nlm.nih.gov/pubmed/24769343 | https://www.ncbi.nlm.nih.gov/pubmed/24769343 | ||
<references/> | <references/> | ||
[[Category:Toxicology]] | |||
Revision as of 19:46, 21 August 2019
Background
- Analogue of clonidine and agonist at alpha 2 adrenergic receptor
- Veterinary sedative, anesthetic, analgesic, and muscle relaxant
- Human drug of abuse, usually as drug adulterant
Clinical Features
Differential Diagnosis
- See Bradycardia, Hypotension
Sedative/hypnotic toxicity
- Absinthe
- Barbiturates
- Benzodiazepines
- Chloral hydrate
- Gamma hydroxybutyrate (GHB)
- Baclofen toxicity
- Opioids
- Toxic alcohols
- Xylazine toxicity
Evaluation
- Evaluate for alternate etiologies
- Clinical diagnosis
Management
- Supportive: address airway/respiratory drive/blood pressure, atropine for bradycardia
Disposition
- Admit if not back to baseline