Dialysis-associated hypotension: Difference between revisions

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==Background==
==Background==
*Most frequent complication of hemodialysis (20%-30% of tx)
*Most frequent complication of hemodialysis (20%-30% of treatment)
*Timing of intradialytic hypotension is helpful in formulating DDX:
**Hypotension early in session usually due to preexisting hypovolemia
**Hypotension during the session is often due to blood loss (from tubing or filter leak)
**Hypotension near the end usually result of excessive ultrafiltration
***Underestimation of pt's ideal blood volume (dry weight)
***Also consider pericardial or cardiac disease


==Clinical Features==
==Clinical Features==
*N/V
*[[Nausea/vomiting]]
*Anxiety
*[[Anxiety]]
*Dizziness
*[[Dizziness]]
*Orthostatic hypotension
*Orthostatic [[hypotension]]
*Syncope
*[[Syncope]]


==Diagnosis==
==Differential Diagnosis==
#Assess:
*Excessive ultrafiltration
##Volume status (US)
**> 0.35 ml/min/kg
##Cardiac function
**>20% plasma volume
##Pericardial disease
*Predialytic volume loss
##Infection
**GI losses (e.g. [[vomiting]], [[diarrhea]])
##GI bleeding
**Decreased oral intake
*Intradialytic volume loss
**Tube and hemodialyzer blood losses
*Postdialytic volume loss
**Vascular access blood loss
*[[Hemorrhage]]
*Medication effects
**[[Antihypertensives]]
**[[Opioids]]
*Decreased vascular tone ([[sepsis]])
*Cardiac dysfunction
**[[LVH]], [[myocardial ischemia|ischemia]], [[hypoxia]], [[arrhythmia]], pericardial [[tamponade]]
*Pericardial disease
**[[pericardial effusion|Effusion]]
**[[Tamponade]]
*[[Hemolytic anemia|Hemolysis]]


==Differential Diagnosis==
#Excessive ultrafiltration
#Predialytic volume loss
##GI losses
##Decreased oral intake
#Intradialytic volume loss
##Tube and hemodialyzer blood losses
#Postdialytic volume loss
##Vascular access blood loss
#Medication effects
##Antihypertensives
##Opiates
#Decreased vascular tone (sepsis)
#Cardiac dysfunction
##LVH, ischemia, hypoxia, arrhythmia, pericardial tamponade
#Pericardial disease
##Effusion
##Tamponade
{{Dialysis complications DDX}}
{{Dialysis complications DDX}}


==Workup==
==Evaluation==
Assess:
*Volume status (US)
*Cardiac function
*Pericardial disease
*Infection
*GI bleeding
 
===Evaluation by [[Hypotension]]Timing===
*Early in session: usually due to preexisting [[hypovolemia]]
*During the session: often due to blood loss (from tubing or filter leak)
*Near the end: usually result of excessive ultrafiltration
**Underestimation of patient's ideal blood volume (dry weight)
**Also consider pericardial or cardiac disease


==Management==
==Management==
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==External Links==
==External Links==


==Sources==
==References==
<references/>
<references/>


[[Category:Nephro]]
[[Category:Renal]]

Latest revision as of 16:23, 16 October 2019

Background

  • Most frequent complication of hemodialysis (20%-30% of treatment)

Clinical Features

Differential Diagnosis

Dialysis Complications

Evaluation

Assess:

  • Volume status (US)
  • Cardiac function
  • Pericardial disease
  • Infection
  • GI bleeding

Evaluation by HypotensionTiming

  • Early in session: usually due to preexisting hypovolemia
  • During the session: often due to blood loss (from tubing or filter leak)
  • Near the end: usually result of excessive ultrafiltration
    • Underestimation of patient's ideal blood volume (dry weight)
    • Also consider pericardial or cardiac disease

Management

Disposition

See Also

External Links

References