EBQ:IST-3: Difference between revisions

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==Clinical Question==
==Clinical Question==
Can use of fibrinolytics for acute ischemic stroke be extended to a wider range of patients up to 6 hours?


==Conclusion==
==Conclusion==

Revision as of 06:08, 4 November 2014

incomplete Journal Club Article
IST-3 collaborative group. "The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.". Lancet. 2012. 379(9834):2352 - 2363.
PubMed Full text

Clinical Question

Can use of fibrinolytics for acute ischemic stroke be extended to a wider range of patients up to 6 hours?

Conclusion

Major Points

Inclusion Criteria

Exclusion Criteria

Interventions

Outcome

Primary Outcomes

Secondary Outcomes

Subgroup analysis

Criticisms

Funding

UK Medical Research Council, Health Foundation UK, Stroke Association UK, Research Council of Norway, Arbetsmarknadens Partners Forsakringsbolag (AFA) Insurances Sweden, Swedish Heart Lung Fund, The Foundation of Marianne and Marcus Wallenberg, Polish Ministry of Science and Education, the Australian Heart Foundation, Australian National Health and Medical Research Council (NHMRC), Swiss National Research Foundation, Swiss Heart Foundation, Assessorato alla Sanita, Regione dell'Umbria, Italy, and Danube University.

Sources