Sheehan's syndrome: Difference between revisions
m (Rossdonaldson1 moved page Sheehan Syndrome to Sheehan's syndrome) |
|||
| Line 22: | Line 22: | ||
==Management== | ==Management== | ||
*Currently no treatment is available but there is an ongoing open-label small pilot study looking at using recombinant human prolactin | |||
==Disposition== | ==Disposition== | ||
Revision as of 18:00, 7 October 2021
Background
- Also known as postpartum hypopituitarism
- Caused by pituitary hypoperfusion and infarction usually in the setting of postpartum hemorrhage
- During pregnancy there is enlargement of the pituitary gland predisposing it to ischemia in low-flow states
Clinical Features
- Symptoms consistent with adrenal insufficiency, hypothyroidism and hypogonadism
- Inability to lactate
- Amenorrhea or oligomenorrhea
- Fatigue
- Cold intolerance
- Lethargy
- Weight loss
Differential Diagnosis
Evaluation
Workup
Diagnosis
Management
- Currently no treatment is available but there is an ongoing open-label small pilot study looking at using recombinant human prolactin