Antidotes: Difference between revisions
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| [[Acetaminophen (Tylenol)|Acetaminophen]] | | [[Acetaminophen (Tylenol)|Acetaminophen]] | ||
| | | | ||
N- | [[N-Acetylcysteine]] | ||
150mg/kg IV load over 60min; followed by 50mg/kg IV over 4hr and then 100mg/kg IV over 16hr | 150mg/kg IV load over 60min; followed by 50mg/kg IV over 4hr and then 100mg/kg IV over 16hr | ||
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|- | |- | ||
| Arsenic | | [[Arsenic]] | ||
| Dimercaprol (BAL) | | Dimercaprol (BAL) | ||
|- | |- | ||
| Benzodiazepines | | [[Benzodiazepines]] | ||
| | | | ||
Flumazenil | Flumazenil | ||
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| [[Beta-Blocker Toxicity|Beta blockers]] | | [[Beta-Blocker Toxicity|Beta blockers]] | ||
| | | | ||
Glucagon | [[Glucagon]] | ||
Adult: 3-10mg IV | Adult: 3-10mg IV | ||
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| | | | ||
Calcium chloride 10% | [[Calcium chloride]] 10% | ||
Adult: 10 mL IV | Adult: 10 mL IV | ||
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|- | |- | ||
| | | | ||
Clonidine | [[Clonidine Toxicity|Clonidine]] | ||
| | | | ||
Naloxone | [[Naloxone]] | ||
Adult: 0.4-2mg IV | Adult: 0.4-2mg IV | ||
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|- | |- | ||
| Lead | | [[Lead toxicity|Lead]] | ||
| EDTA, succimer | | EDTA, succimer | ||
|- | |- | ||
| Mercury | | [[Mercury Poisoning|Mercury]] | ||
| Dimercaprol (BAL) | | Dimercaprol (BAL) | ||
|- | |- | ||
| Methanol | | [[Methanol Toxicity|Methanol]] | ||
| Fomepizole | | Fomepizole | ||
15mi/kg IV; then 10mg/kg q12h<br> | 15mi/kg IV; then 10mg/kg q12h<br> | ||
|- | |- | ||
| | | [[Methemoglobinemia]] | ||
| Methylene blue | | Methylene blue | ||
|- | |- | ||
| [[Opioid Overdose|Opiods]] | | [[Opioid Overdose|Opiods]] | ||
| | | [[Naloxone]] | ||
|- | |- | ||
| [[Organophosphates]] | | [[Organophosphates]] | ||
| Atropine+pralidoxime | | [[Atropine]]+pralidoxime | ||
|- | |- | ||
| Sulfonylurea | | [[Sulfonylurea Toxicity|Sulfonylurea]] | ||
| | | | ||
Octreotide | Octreotide | ||
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|- | |- | ||
| Valproate | | [[Valproic acid toxicity|Valproate]] | ||
| Carnitine | | Carnitine | ||
|- | |- | ||
| [[Warfarin (Coumadin) Reversal|Warfarin]] | | [[Warfarin (Coumadin) Reversal|Warfarin]] | ||
| | | [[Vitamin K]], [[Fresh Frozen Plasma|FFP]], Prothrombin Complex Concentrates | ||
|} | |} | ||
Revision as of 10:32, 4 March 2015
|
TOXIN |
ANTIDOTE |
| Acetaminophen |
150mg/kg IV load over 60min; followed by 50mg/kg IV over 4hr and then 100mg/kg IV over 16hr |
| Tricyclic (TCA) Toxicity |
Bicarbonate 1-2mEq/kg IV bolus followed by 2mEq/kg/hr IV infusion |
| Arsenic | Dimercaprol (BAL) |
| Benzodiazepines |
Flumazenil Adult: 0.2mg IV Peds: 0.01mg/kg IV |
| Beta blockers |
Adult: 3-10mg IV Peds: 50-150mcg/kg IV |
|
Calcium chloride 10% Adult: 10 mL IV Peds: 0.2-0.25 mL/kg IV | |
|
Adult: 0.4-2mg IV Peds: 0.1mg/kg IV (max 2mg) | |
| Cyanide |
Kit- Hydroxycobalamin, Sodium nitrite, Sodium thiosulfate |
| Digoxin | Dig Immune Fab |
| Ethylene glycol |
Fomepizole 15mi/kg IV; then 10mg/kg q12h |
| Fluoride | Calcium Gluconate |
| Heparin |
Protamine Adult: 25-50mg IV (empiric dose) over 10 minutes Peds: 0.6mg/kg IV (empiric dose) rapid protamine infusion causes hypotension[1] |
| Iron | Deferoxamine |
| Isoniazid (INH) |
Pyridoxine (Vit B6) Adult: 5gm IV Peds: 1gm/kg regardless of age [2] |
| Lead | EDTA, succimer |
| Mercury | Dimercaprol (BAL) |
| Methanol | Fomepizole
15mi/kg IV; then 10mg/kg q12h |
| Methemoglobinemia | Methylene blue |
| Opiods | Naloxone |
| Organophosphates | Atropine+pralidoxime |
| Sulfonylurea |
Octreotide Adult: 50–100mcg SC q6hr Peds: 1mcg/kg SC q6hr |
| Valproate | Carnitine |
| Warfarin | Vitamin K, FFP, Prothrombin Complex Concentrates |
Source
<references>