Naloxone: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===[[Opioid toxicity]]=== | |||
*Bolus (May repeat q3min up to max dose 10mg | |||
**Apneic or near-apneic - 2mg IV | |||
**Opioid-naive with minimal respiratory depression - 0.4mg IV | |||
**Opioid-dependent with minimal respiratory depression - 0.05mg IV | |||
*Infusion | |||
**Only give if the pt responded to the bolus and required repeat administration | |||
**Step 1: Determine the "wake-up dose" or bolus required to wake the pt | |||
**Step 2: Give 2/3 of the "wake-up dose" per hr; mix in 1L D5W | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 16:23, 12 March 2015
General
- Type: Opiod antagonists
- Dosage Forms:
- Common Trade Names: Narcan
Adult Dosing
Opioid toxicity
- Bolus (May repeat q3min up to max dose 10mg
- Apneic or near-apneic - 2mg IV
- Opioid-naive with minimal respiratory depression - 0.4mg IV
- Opioid-dependent with minimal respiratory depression - 0.05mg IV
- Infusion
- Only give if the pt responded to the bolus and required repeat administration
- Step 1: Determine the "wake-up dose" or bolus required to wake the pt
- Step 2: Give 2/3 of the "wake-up dose" per hr; mix in 1L D5W
Pediatric Dosing
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: