Lisinopril: Difference between revisions
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==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: D | ||
*Lactation: | *Lactation: Safety unknown | ||
*Renal Dosing | *Renal Dosing | ||
**Adult | **Adult: CrCl < 30, start 2.5 mg qday, max 40 mg q/day | ||
**Pediatric | **Pediatric Cr Cl 30-50: decrease dose 50%, CrCl < 30, avoid use | ||
*Hepatic Dosing | *Hepatic Dosing | ||
**Adult | **Adult: Not defined | ||
**Pediatric | **Pediatric: Not defined | ||
==Contraindications== | ==Contraindications== | ||
Revision as of 02:21, 1 April 2015
General
- Type: ACE inhibitor
- Dosage Forms: 2.5, 5, 10, 20, 30, 40
- Common Trade Names: Prinivil, Zestril
General information: doses > 40 mg/day rarely more effective, decreased efficacy as mono therapy in african-american patients
Adult Dosing
- HTN: 10 - 40 mg PO Qday, max 80 mg/day
Pediatric Dosing
- 6-16 year old: 0.07 mg/kg PO qday, max 40 mg/day
Special Populations
- Pregnancy Rating: D
- Lactation: Safety unknown
- Renal Dosing
- Adult: CrCl < 30, start 2.5 mg qday, max 40 mg q/day
- Pediatric Cr Cl 30-50: decrease dose 50%, CrCl < 30, avoid use
- Hepatic Dosing
- Adult: Not defined
- Pediatric: Not defined
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: