Anticonvulsants: Difference between revisions

Latest revision as of 20:44, 19 October 2022

Drug	Dose	Infusion Rate (Minutes)	Age	Comments/Cautions
Levetiracetam	60 mg/kg/dose IV/IO MAX: 4500 mg/dose	≥5	Any	Most commonly used agent
Fosphenytoin	20 mg phenytoin equivalent (PE)/kg/dose IV/IO/IM MAX: 1000 PE/dose	≥10	Any	Choose alternate drug if on phenytoin at home; may decrease BP/HR; not for toxin-induced seizures
Valproic acid	40 mg/kg/dose IV/IO MAX: 3000 mg/dose	≥10	≥2 years	Caution in patients with liver dysfunction, mitochondrial disease, urea disorder, thrombocytopenia, or unexplained developmental delay
Phenytoin	20 mg/kg/dose IV/IO MAX: 1000 mg/dose	≥20	Any	Choose alternate drug if on phenytoin at home; may decrease BP/HR; not for toxin-induced seizures
Phenobarbital	20 mg/kg/dose IV/IO MAX: 1000 mg/dose	≥20	<6 months	First line for most neonatal seizures. Respiratory depression, especially in combination with benzodiazepines

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-*[[Carbamazepine]]
+*[[Carbamazepine]] (Tegretol)
+*[[Clobazam]] (Onfi)
+*[[Diazepam]] (Valium)
+*[[Ethosuximide]]
 *[[Fosphenytoin]]
-*[[Gabapentin]]
+*[[Gabapentin]] (Neurontin)
-*[[Lacosamide]]
+*[[Lacosamide]] (Vimpat)
-*[[Lamotrigine]]
+*[[Lamotrigine]] (Lamictal)
-*[[Levetiracetam]]
+*[[Levetiracetam]] (Keppra)
-*[[Lorazepam]]
+*[[Lorazepam]] (Ativan)
+*[[Midazolam]] (Versed)
+*[[Oxcarbazepine]] (Trileptal)
+*[[Pentobarbital]]
 *[[Phenobarbital]]
-*[[Phenytoin]]
+*[[Phenytoin]] (Dilantin)
-*[[Valproate]]
+*[[Propofol]]
+*[[Topiramate]] (Topamax)
+*[[Valproate]] (Depakote)
+*[[Zonisamide]]
-[[Category:Drugs]]
+{{Pediatric anticonvulsants}}
+==See Also==
+*[[Seizure]]
+*[[Anticonvulsant levels and reloading]]
+[[Category:Pharmacology]]
+[[Category:Neurology]]