Neuroblastoma (peds): Difference between revisions

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Revision as of 06:47, 1 May 2015

Background

  • Arises from primitive ganglion cells of sympathetic nervous system
  • Most common neoplasm in 1st yr of life
  • May arise anywhere along sympathetic nervous system
    • Adrenal gland (40%)
    • Abdomen (25%)
    • Chest (15%)

Diagnosis

  • Depends on location
    • Large, painless abdominal mass
    • Compression of bowel/bladder
    • Horner syndrome
    • Spinal cord compression
  • Opsoclonus-myoclonus
    • Highly a/w neuroblastoma
  • Neutropenia/pancytopenia suggests bone marrow involvement

Work-Up

  • CXR

Treatment

  • Admssion for tumor biopsy

Source

Tintinalli