Herpes zoster oticus: Difference between revisions
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==Background== | ==Background== | ||
*Also know as "Ramsay Hunt syndrome" | *Also know as "Ramsay Hunt syndrome" | ||
* | *Acute peripheral facial neuropathy associated with erythematous vesicular rash of the skin of the ear canal, auricle, or mucous membrane of the oropharynx | ||
*Associated facial paralysis usually involving CN VII but may involve CN VIII | *Associated facial paralysis usually involving [[Cranial nerve palsies|CN VII]] but may involve [[Cranial nerve palsies|CN VIII]] | ||
**geniculate ganglion: movements of the facial muscles, sensation of parts of the ear and ear canal, taste function of the tongue, and lubrication of the eyes and oral mucosa | **geniculate ganglion: movements of the facial muscles, sensation of parts of the ear and ear canal, taste function of the tongue, and lubrication of the eyes and oral mucosa | ||
**vestibulocochlear nerve is close to the geniculate ganglion, patients may complain of tinnitus, hearing loss, and vertigo | **vestibulocochlear nerve is close to the geniculate ganglion, patients may complain of tinnitus, hearing loss, and vertigo | ||
*Caused by [[herpes zoster]] | *Caused by [[herpes zoster]] | ||
{{Herpes viruses}} | |||
==Clinical Features== | ==Clinical Features== | ||
*URI symptoms common for 1-3 days prior | [[File:Ramsey Hunt Syndrome.png|thumb|Ear findings and facial droop classic for Ramsey Hunt Syndrome.]] | ||
*Paroxysmal pain deep within ear: radiates outward into the pinna of the ear<ref>Ryu EW, Lee HY, Lee SY, Park MS, Yeo SG. Clinical manifestations and prognosis of patients with Ramsay Hunt syndrome. Am J Otolaryngol. Nov 8 2011</ref> | *[[URI]] symptoms common for 1-3 days prior | ||
*Paroxysmal [[earache|pain]] deep within ear: radiates outward into the pinna of the ear<ref>Ryu EW, Lee HY, Lee SY, Park MS, Yeo SG. Clinical manifestations and prognosis of patients with Ramsay Hunt syndrome. Am J Otolaryngol. Nov 8 2011</ref> | |||
**Usually precedes the rash by several hours and even days | **Usually precedes the rash by several hours and even days | ||
**Erythema and Swelling of auricle | **Erythema and Swelling of auricle | ||
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==Management== | ==Management== | ||
''Most effective when started within 3 days of symptom onset'' | ''Most effective when started within 3 days of symptom onset'' | ||
*Oral analgesia | *Oral [[analgesia]] | ||
*Antiviral Options<ref>Uscategu T. et al. Antiviral therapy for Ramsay Hunt syndrome in adults. Cochrane Database Syst Rev. 2008</ref> | *[[Antiviral]] Options<ref>Uscategu T. et al. Antiviral therapy for Ramsay Hunt syndrome in adults. Cochrane Database Syst Rev. 2008</ref> | ||
**[[Acyclovir]] 800mg 5 times a day x 7 days | **[[Acyclovir]] 800mg 5 times a day x 7 days | ||
**[[ | **[[Famciclovir]] 500mg TID x 7 days | ||
**[[Valacyclovir]] 1000mg TID x 7 days | **[[Valacyclovir]] 1000mg TID x 7 days | ||
*[[Prednisone]] 60mg qday x 7 days | *[[Prednisone]] 60mg qday x 7 days | ||
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==See Also== | ==See Also== | ||
*[[Herpes zoster ophthalmicus]] | *[[Herpes zoster ophthalmicus]] | ||
==References== | ==References== | ||
Latest revision as of 20:00, 17 April 2024
Background
- Also know as "Ramsay Hunt syndrome"
- Acute peripheral facial neuropathy associated with erythematous vesicular rash of the skin of the ear canal, auricle, or mucous membrane of the oropharynx
- Associated facial paralysis usually involving CN VII but may involve CN VIII
- geniculate ganglion: movements of the facial muscles, sensation of parts of the ear and ear canal, taste function of the tongue, and lubrication of the eyes and oral mucosa
- vestibulocochlear nerve is close to the geniculate ganglion, patients may complain of tinnitus, hearing loss, and vertigo
- Caused by herpes zoster
Herpes Virus Types
- HHV-1: Herpes Simplex Virus-1
- HHV-2: Herpes Simplex Virus-2
- Herpes B virus
- Varicella zoster virus
- Varicella (Chickenpox)
- Herpes zoster (Shingles)
- Herpes zoster ophthalmicus
- Herpes zoster oticus (Ramsay Hunt syndrome)
- HHV-6 (Roseola infantum)
- HHV-8 (Kaposi’s sarcoma)
- Epstein-Barr virus
- Cytomegalovirus
Clinical Features
- URI symptoms common for 1-3 days prior
- Paroxysmal pain deep within ear: radiates outward into the pinna of the ear[1]
- Usually precedes the rash by several hours and even days
- Erythema and Swelling of auricle
- Vesicles within external ear canal and on auricle
- Facial pain
- Develop over 3-7 days
Differential Diagnosis
Facial paralysis
- Bell's palsy
- CVA
- Trigeminal neuralgia
- Tick paralysis
- Herpes zoster oticus (Ramsay Hunt syndrome)
- CNS tumor
- Acoustic neuroma or other cerebellopontine angle lesions
- Meningioma
- Cerebellar pontine angle
- Facial nerve schwannoma
- Parotid
- Sarcoma
- Anesthesia nerve blocks
- Cerebral Aneurysms (vertebral, basilar, or carotid)
Ear Diagnoses
External
- Auricular hematoma
- Auricular perichondritis
- Cholesteatoma
- Contact dermatitis
- Ear foreign body
- Herpes zoster oticus (Ramsay Hunt syndrome)
- Malignant otitis externa
- Otitis externa
- Otomycosis
- Tympanic membrane rupture
Internal
- Acute otitis media
- Chronic otitis media
- Mastoiditis
Inner/vestibular
Varicella zoster virus
- Varicella (Chickenpox)
- Herpes zoster (Shingles)
- Herpes zoster ophthalmicus
- Herpes zoster oticus (Ramsay Hunt syndrome)
Evaluation
- Otoscopy
- Neuro exam focusing on Cranial nerve, crossed findings, upper and lower motor neuron involvement
Management
Most effective when started within 3 days of symptom onset
- Oral analgesia
- Antiviral Options[2]
- Acyclovir 800mg 5 times a day x 7 days
- Famciclovir 500mg TID x 7 days
- Valacyclovir 1000mg TID x 7 days
- Prednisone 60mg qday x 7 days
Disposition
- Outpatient primary care follow-up
Prognosis
- Poor prognostic factors for good functional recovery include[3]
- age older than 50 years
- complete facial paralysis
- lack of CN VII nerve excitability
See Also
References
- ↑ Ryu EW, Lee HY, Lee SY, Park MS, Yeo SG. Clinical manifestations and prognosis of patients with Ramsay Hunt syndrome. Am J Otolaryngol. Nov 8 2011
- ↑ Uscategu T. et al. Antiviral therapy for Ramsay Hunt syndrome in adults. Cochrane Database Syst Rev. 2008
- ↑ Ryu EW, Lee HY, Lee SY, Park MS, Yeo SG. Clinical manifestations and prognosis of patients with Ramsay Hunt syndrome. Am J Otolaryngol. Nov 8 2011
