Impetigo: Difference between revisions
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==Background== | ==Background== | ||
{{Skin anatomy background images}} | |||
*Superficial epidermal infection characterized by amber crusts (nonbullous) or vesicles (bullous) | *Superficial epidermal infection characterized by amber crusts (nonbullous) or vesicles (bullous) | ||
*May be super-infection or primary infection | *May be super-infection or primary infection | ||
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**Some cases caused by [[MRSA]] | **Some cases caused by [[MRSA]] | ||
*Uncommonly painful, but usually pruritic | *Uncommonly painful, but usually pruritic | ||
*Regional lymphadenopathy is common | *Regional [[lymphadenopathy]] is common | ||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Latest revision as of 16:35, 11 December 2024
Background
- Superficial epidermal infection characterized by amber crusts (nonbullous) or vesicles (bullous)
- May be super-infection or primary infection
- Typical causative organisms are Staphylococcus aureus or Streptococcus pyogenes
- Fever and systemic signs are uncommon
- Post-streptococcal glomerular nephritis is a possible complication, and incidence is not reduced by antibiotic therapy
- Highly contagious and easily transmittable
Clinical Features
- Nonbullous
- Erythematous macules/papules develop into vesicles which become pustular and rupture
- As rupture release yellow fluid which dries to form stratified golden crust
- Erythematous macules/papules develop into vesicles which become pustular and rupture
- Bullous
- Bullae form as result of staph toxin
- Some cases caused by MRSA
- Uncommonly painful, but usually pruritic
- Regional lymphadenopathy is common
Differential Diagnosis
Other Rash
- Acute generalized exanthematous pustulosis
- Allergic reaction
- Aphthous stomatitis
- Atopic dermatitis
- Coxsackie
- Dermatitis herpetiformis
- Exfoliative erythroderma
- Impetigo
- Pellagra
- Pityriasis rosea
- Serum Sickness
- Tinea capitus
- Tinea corporis
- Vitiligo
Evaluation
- Clinical diagnosis
Management
Antibiotics
Coverage for MSSA, MRSA, Group A Strep
Topical therapy
- Mupirocin (Bactroban) 2% ointment q8hrs x 5 days
- For nonbullous impetigo, topic antibiotics are as effective as oral antibiotics
Oral Therapy
- Cephalexin 500mg (6.25mg/kg) PO q6hrs for 10 days OR
- Amoxicillin/Clavulanate 875mg (12.5mg/kg) PO q12hrs daily x 10 days OR
- Clindamycin 450mg PO q8hrs daily (or 10mg/kg PO q6hrs) for 10 days OR
- Dicloxacillin 500mg (3mg/kg) PO q6hrs daily x 10 days
Disposition
- Outpatient