Benzodiazepines: Difference between revisions

Latest revision as of 14:31, 18 July 2025

Background

A Benzodiazepine is a GABA receptor agonist.
Binding results in inhibition of neuronal firing

Table

Generic (Trade Name)	Equivalent Oral Dose	Onset (minutes)	Duration (hours)
Alprazolam (Xanax)	0.5mg	15-30	6-12
Chlordiazepoxide (Librium)	25mg	30-60	24-48
Diazepam (Valium)	5mg	2-5 (IV)	6-12
Flurazepam (Dalmane)	15mg	15-60	24-48
Lorazepam (Ativan)	1mg	5-20(IV); 15-30 (IM)	6-8
Midazolam (Versed)	5mg	15(IM)	1-2
Oxazepam (Serax)	15mg	30-60	6-8
Temazepam (Restoril)	15mg	30	2-4

Uses

Sedation
Seizures
Alcohol Withdrawal
Panic disorder, Generalized Anxiety Disorder, Anxiety
Insomnia
Muscle Spasms

References

Authors:

@@ Line 1: / Line 1: @@
 ==Background==
-*Class of GABA Receptor Agonists
+*A [[Benzodiazepine]] is a GABA receptor agonist.
 *Binding results in inhibition of neuronal firing
-==Commonly Used Benzodiazepines==
+==Table==
-*Alprazolam (Xanax)
+{| class="wikitable"
-*Chlordiazepoxide (Librium)
+| align="center" style="background:#f0f0f0;"|'''Generic (Trade Name)'''
-*Diazepam (Valium)
+| align="center" style="background:#f0f0f0;"|'''Equivalent Oral Dose'''
-*Flurazepam (Dalmane)
+| align="center" style="background:#f0f0f0;"|'''Onset (minutes)'''
-*Lorazepam (Ativan)
+| align="center" style="background:#f0f0f0;"|'''Duration (hours)'''
-*Midazolam (Versed)
+|-
-*Oxazepam (Serax)
+| [[Has DrugName::Alprazolam]] (Xanax)||0.5mg||15-30 || 6-12
+|-
+| [[Has DrugName::Chlordiazepoxide]] (Librium)||25mg||30-60 || 24-48
+|-
+| [[Has DrugName::Diazepam]] (Valium)||5mg||2-5 (IV) ||6-12
+|-
+| [[Has DrugName::Flurazepam]] (Dalmane)||15mg||15-60 || 24-48
+|-
+| [[Has DrugName::Lorazepam]] (Ativan)||1mg||5-20(IV); 15-30 (IM)||6-8
+|-
+| [[Has DrugName::Midazolam]] (Versed)||5mg||15(IM)||1-2
+|-
+| [[Has DrugName::Oxazepam]] (Serax)||15mg|| 30-60 ||6-8
+|-
+| [[Has DrugName::Temazepam]] (Restoril)||15mg||30||2-4
+|}
 ==Uses==
@@ Line 16: / Line 32: @@
 *[[Seizure#Treatment|Seizures]]
 *[[Alcohol Withdrawal]]
-*Panic Disorder
+*[[Panic attack|Panic disorder]], Generalized Anxiety Disorder, Anxiety
-*Generalized Anxiety Disorder
+*[[Insomnia]]
-*Insomnia
-*Anxiety
 *Muscle Spasms
-==Workup==
-==Management==
-==Disposition==
 ==See Also==
+*[[Benzodiazepine Toxicity]]
+*[[Intranasal Sedation]]
+*[[Sedation (main)]]
-==Sources==
+==References==
 <references/>
+[[Category:Pharmacology]] [[Category:Neurology]] [[Category:Psychiatry]]