Neonatal lower gastrointestinal bleeding: Difference between revisions

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==Background==
==Background==
Mortality from acute GIB in children is low with rectal bleeding in infancy often self-limited condition
 
Acute GI bleeding in children carries ''low'' mortality and is often a self-limited condition in infants<ref>Romano C1, Oliva S1, Martellossi S1, Miele E1, Arrigo S1, Graziani MG1, Cardile S1, Gaiani F1, de’Angelis GL1, Torroni F1. Pediatric gastrointestinal bleeding: Perspectives from the Italian Society of Pediatric Gastroenterology. World J Gastroenterol. 2017 Feb 28;23(8):1328-1337. PMID: 28293079</ref><ref>Arvola T1, Ruuska T, Keränen J, Hyöty H, Salminen S, Isolauri E. Rectal bleeding in infancy: clinical, allergological, and microbiological examination.</ref>
 


==Clinical Features==
==Clinical Features==
*blood stool
 
*hemodynamic instability if emergent and not minimal bleeding
*Bloody stool
*+/- additional features of underlying condition
*+/- signs of [[Special:MyLanguage/anemia|anemia]], [[Special:MyLanguage/shock|shock]] if significant bleed
 


==Differential Diagnosis==
==Differential Diagnosis==
*Emergent  
 
**[[necrotizing enterocolitis]]
*Emergent: typically do not present with isolated hematochezia
**[[malrotation with volvulus]]
**[[Special:MyLanguage/Necrotizing enterocolitis|Necrotizing enterocolitis]]
**[[Hirschsprung disease]]
**Malrotation with [[Special:MyLanguage/volvulus (peds)|volvulus]]
**systemtic coagulopathy (see other bleeding symptoms (cephalohematoma, mucocutaneous bleeding, petechiae)
**[[Special:MyLanguage/Hirschsprung's disease|Hirschsprung's disease]]
***vit K deficiency (was it given after birth)
**[[Special:MyLanguage/Coagulopathy|Coagulopathy]] (see other bleeding symptoms (cephalohematoma, mucocutaneous bleeding, petechiae)
***maternal thrombocytopenia
***[[Special:MyLanguage/Vitamin K deficiency|Vitamin K deficiency]] (if not given after delivery)
***DIC
***Maternal [[Special:MyLanguage/thrombocytopenia|thrombocytopenia]]
**Infectious colitis
***[[Special:MyLanguage/DIC|DIC]]
**Infectious [[Special:MyLanguage/colitis|colitis]]
**[[Special:MyLanguage/FPIES|FPIES]]


*Other conditions
*Other conditions
**Swallowed maternal blood
**Swallowed maternal blood (e.g. from chapped nipples)
***Apt test :qualitative test using alkali to detect maternal hemoglobin, fetal hgb resistant to alkali stays pink, adult hgb hydrolyzed by alkali turn yellow brown
**Milk protein enterocolitis
**Milk protein entercolitis
**Perianal/rectal [[Special:MyLanguage/anal fissure|fissure]]
**Perianal/rectal fissure
 


==Evaluation==
==Evaluation==
*hemodynamically stable treat for shock
 
*examine stool directly and test for blood
*Examine stool directly and test for blood
*abnormal abdominal exam (distension, tenderness, abnormal bowel sounds) abdominal plain film
**Apt test: distinguishes maternal versus infant's blood (fetal Hgb is resistant to alkali and stays pink, adult Hgb hydrolyzed by alkali--> yellow/brown)
*Evaluate for underlying emergent etiology if sick or suggestive presentation
**abnormal abdominal exam (distension, tenderness, abnormal bowel sounds): [[Special:MyLanguage/KUB|abdominal plain film]]
 


==Management==
==Management==
*emergent conditions don't typically present with only hematochezia
 
*milk or soy protein induced colitis are well appearing, stools with low-moderate blood, trial eliminating milk and soy from the diet
*Treat underlying condition, resuscitate prn
*If well-appearing with low-moderate blood and suspect milk or soy protein induced colitis, trial eliminating milk/soy  are well appearing, stools with low-moderate blood, trial eliminating milk and soy from the diet
 


==Disposition==
==Disposition==
*depending on etiology
 
*Dependant on degree of bleeding and underlying etiology; most can be discharged
 


==See Also==
==See Also==
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==References==
==References==
*https://pedemmorsels.com/neonate-with-bloody-stool/
*https://pedemmorsels.com/neonate-with-bloody-stool/
*https://www.uptodate.com/contents/lower-gastrointestinal-bleeding-in-children-causes-and-diagnostic-approach
*https://www.uptodate.com/contents/lower-gastrointestinal-bleeding-in-children-causes-and-diagnostic-approach


<references/>
<references/>
[[Category:Pediatrics]] [[Category:GI]] [[category:Symptoms]]
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Latest revision as of 23:47, 4 January 2026


Background

Acute GI bleeding in children carries low mortality and is often a self-limited condition in infants[1][2]


Clinical Features

  • Bloody stool
  • +/- additional features of underlying condition
  • +/- signs of anemia, shock if significant bleed


Differential Diagnosis

  • Other conditions
    • Swallowed maternal blood (e.g. from chapped nipples)
    • Milk protein enterocolitis
    • Perianal/rectal fissure


Evaluation

  • Examine stool directly and test for blood
    • Apt test: distinguishes maternal versus infant's blood (fetal Hgb is resistant to alkali and stays pink, adult Hgb hydrolyzed by alkali--> yellow/brown)
  • Evaluate for underlying emergent etiology if sick or suggestive presentation


Management

  • Treat underlying condition, resuscitate prn
  • If well-appearing with low-moderate blood and suspect milk or soy protein induced colitis, trial eliminating milk/soy are well appearing, stools with low-moderate blood, trial eliminating milk and soy from the diet


Disposition

  • Dependant on degree of bleeding and underlying etiology; most can be discharged


See Also

External Links

References

  1. Romano C1, Oliva S1, Martellossi S1, Miele E1, Arrigo S1, Graziani MG1, Cardile S1, Gaiani F1, de’Angelis GL1, Torroni F1. Pediatric gastrointestinal bleeding: Perspectives from the Italian Society of Pediatric Gastroenterology. World J Gastroenterol. 2017 Feb 28;23(8):1328-1337. PMID: 28293079
  2. Arvola T1, Ruuska T, Keränen J, Hyöty H, Salminen S, Isolauri E. Rectal bleeding in infancy: clinical, allergological, and microbiological examination.