Template:Septic Arthritis Antibiotics: Difference between revisions
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''For adults treatment should be divided into Gonococcal and Non-Gonococcal | ''For adults treatment should be divided into Gonococcal and Non-Gonococcal | ||
====[[Gonococcal]]==== | ====[[Gonococcal]]==== | ||
* | *{{AntibioticDose|drug=Ceftriaxone|dose=1g IV once daily|context=Gonococcal}} | ||
* | *{{AntibioticDose|drug=Cefixime|dose=400 mg PO BID|context=Gonococcal, Outpatient}} is an option for outpatient therapy after initial 3 days of [[Ceftriaxone]] | ||
====Non-Gonococcal==== | ====Non-Gonococcal==== | ||
*Treatment should cover [[S. aureus]], [[Streptococcus]], [[Pseudomonas]], [[Enterococcus]], [[ Borrelia burgdorferi| B. burgdorferi]] | *Treatment should cover [[S. aureus]], [[Streptococcus]], [[Pseudomonas]], [[Enterococcus]], [[ Borrelia burgdorferi| B. burgdorferi]] | ||
*Vancomycin 15-20 mg/kg IV BID PLUS any of the following: | *{{AntibioticDose|drug=Vancomycin|dose=15-20 mg/kg IV BID|context=Non-Gonococcal}} PLUS any of the following: | ||
** | **{{AntibioticDose|drug=Ceftriaxone|dose=2g IV once daily|context=Non-Gonococcal}} | ||
** | **{{AntibioticDose|drug=Cefepime|dose=2g IV three times daily|context=Non-Gonococcal}} | ||
** | **{{AntibioticDose|drug=Ceftazidime|dose=2g IV three times daily|context=Non-Gonococcal}} | ||
** | **{{AntibioticDose|drug=Ciprofloxacin|dose=400mg IV three times daily|context=Non-Gonococcal}} | ||
====Pediatrics==== | ====Pediatrics==== | ||
* | *{{AntibioticDose|drug=Ceftriaxone|dose=1g IV once daily|context=Pediatrics|population=Pediatric}} | ||
====[[Sickle Cell]]==== | ====[[Sickle Cell]]==== | ||
''Coverage for [[Salmonella]] and [[Staphylococcus]] spp'' | ''Coverage for [[Salmonella]] and [[Staphylococcus]] spp'' | ||
* | *{{AntibioticDose|drug=Vancomycin|dose=20mg/kg IV twice daily|context=Sickle Cell}} PLUS | ||
**Ciprofloxacin 400mg IV three times daily OR | **{{AntibioticDose|drug=Ciprofloxacin|dose=400mg IV three times daily|context=Sickle Cell}} OR | ||
**Imipenem/ | **{{AntibioticDose|drug=Imipenem/Cilastatin|dose=1g IV three times daily|context=Sickle Cell}} | ||
Revision as of 20:41, 19 March 2026
For adults treatment should be divided into Gonococcal and Non-Gonococcal
Gonococcal
- Ceftriaxone 1g IV once daily
- Cefixime 400 mg PO BID is an option for outpatient therapy after initial 3 days of Ceftriaxone
Non-Gonococcal
- Treatment should cover S. aureus, Streptococcus, Pseudomonas, Enterococcus, B. burgdorferi
- Vancomycin 15-20 mg/kg IV BID PLUS any of the following:
- Ceftriaxone 2g IV once daily
- Cefepime 2g IV three times daily
- Ceftazidime 2g IV three times daily
- Ciprofloxacin 400mg IV three times daily
Pediatrics
- Ceftriaxone 1g IV once daily
Sickle Cell
Coverage for Salmonella and Staphylococcus spp
- Vancomycin 20mg/kg IV twice daily PLUS
- Ciprofloxacin 400mg IV three times daily OR
- Imipenem/Cilastatin 1g IV three times daily
